SEP

PHOSPHOSERINE

Find entries where: SEP

is present as a standalone ligand in 24 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 7 entries

is present in a polymer sequence 1,935 entries

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Chemical Component Summary
Name	PHOSPHOSERINE
Synonyms	PHOSPHONOSERINE
Identifiers	(2S)-2-amino-3-phosphonooxy-propanoic acid
Formula	C₃ H₈ N O₆ P
Molecular Weight	185.072
Type	L-PEPTIDE LINKING
Isomeric SMILES	C([C@@H](C(=O)O)N)OP(=O)(O)O
InChI	InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChIKey	BZQFBWGGLXLEPQ-REOHCLBHSA-N

Chemical Details
Formal Charge	0
Atom Count	19
Chiral Atom Count	1
Bond Count	18
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB04522
Name	Dexfosfoserine
Groups	experimental
Description	The phosphoric acid ester of serine.
Synonyms	Dexfosfoserine Serine phosphate Phosphoserine
Categories	Amino Acids Amino Acids, Neutral Amino Acids, Peptides, and Proteins Phosphoamino Acids
CAS number	407-41-0

Drug Targets

Name	Target Sequence	Pharmacological Action
3-phosphoinositide-dependent protein kinase 1	MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPA...	unknown
Serine/threonine-protein kinase pim-1	MPHEPHEPLTPPFSALPDPAGAPSRRQSRQRPQLSSDSPSAFRASRSHSR...	unknown
Protein kinase C theta type	MSPFLRIGLSNFDCGSCQSCQGEAVNPYCAVLVKEYVESENGQMYIQKKP...	unknown
Glycogen phosphorylase, liver form	-	unknown
Phosphomannomutase/phosphoglucomutase	MSTAKAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPC...	unknown
Glycogen phosphorylase, muscle form	MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPR...	unknown
cAMP-dependent protein kinase catalytic subunit alpha	MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTL...	unknown
Anti-sigma F factor antagonist	MHFQLEMVTRETVVIRLFGELDHHAVEQIRAKISAAIFQGTVTTIIWNLE...	unknown
Fimbrial protein	MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQ...	unknown
Alkaline phosphatase	MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGARRLTGD...	unknown
Rhodopsin	MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVL...	unknown
Serpin B3	MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTA...	unknown
Endo-1,4-beta-xylanase Y	MKNKRVLAKITALVVLLGVFFVLPSNISQLYADYEVVHDTFEVNFDGWCN...	unknown
Serine/threonine-protein kinase TAO2	MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRN...	unknown
Potassium voltage-gated channel subfamily C member 4	MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETY...	unknown
Lithostathine-1-alpha	MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYF...	unknown
Mothers against decapentaplegic homolog 2	MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVK...	unknown
Glutaminase 1	MKELIKEHQKDINPALQLHDWVEYYRPFAANGQSANYIPALGKVNDSQLG...	unknown
Siroheme synthase	MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFT...	unknown
Phosphocarrier protein HPr	MEKKEFHIVAETGIHARPATLLVQTASKFNSDINLEYKGKSVNLKSIMGV...	unknown
Cystic fibrosis transmembrane conductance regulator	MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLS...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682