SFY

4-amino-N-(pyridin-2-yl)benzenesulfonamide

Created:	2012-11-09
Last modified:	2021-03-01

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8 entries where SFY is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	28
Chiral Atom Count	0
Bond Count	29
Aromatic Bond Count	12

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Chemical Component Summary
Name	4-amino-N-(pyridin-2-yl)benzenesulfonamide
Synonyms	Sulfapyridine
Systematic Name (OpenEye OEToolkits)	4-azanyl-N-pyridin-2-yl-benzenesulfonamide
Formula	C₁₁ H₁₁ N₃ O₂ S
Molecular Weight	249.289
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	O=S(=O)(Nc1ncccc1)c2ccc(N)cc2
SMILES	CACTVS	3.370	Nc1ccc(cc1)[S](=O)(=O)Nc2ccccn2
SMILES	OpenEye OEToolkits	1.7.6	c1ccnc(c1)NS(=O)(=O)c2ccc(cc2)N
Canonical SMILES	CACTVS	3.370	Nc1ccc(cc1)[S](=O)(=O)Nc2ccccn2
Canonical SMILES	OpenEye OEToolkits	1.7.6	c1ccnc(c1)NS(=O)(=O)c2ccc(cc2)N
InChI	InChI	1.03	InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
InChIKey	InChI	1.03	GECHUMIMRBOMGK-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00891
Name	Sulfapyridine
Groups	approved
Description	Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Synonyms	Sulfapiridina Sulfapyridinum 2-Sulfanilamidopyridin 4-(2-Pyridinylsulfonyl)aniline N-2-Pyridylsulfanilamide Sulfapyridin N(1)-2-Pyridylsulfanilamide 4-Amino-N-pyridin-2-yl-benzenesulfonamide 2-Sulfanilamidopyridine 2-(p-Aminobenzenesulphonamido)pyridine Solfapiridina 2-Sulfapyridine 2-Sulfanilylaminopyridine Sulfapyridine N(1)-Pyridylsulfanilamide 4-Amino-N,2-pyridinylbenzenesulfonamide 4-[(2-Pyridylamino)sulfonyl]aniline Sulphapyridine
Brand Names	Dagenan Tab 500mg
Indication	For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum
Categories	Amides Amines Aniline Compounds Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Benzene Derivatives Benzenesulfonamides Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Dermatologicals Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Methemoglobinemia Associated Agents Short-Acting Antibacterial Sulfonamides Sulfanilamides Sulfonamides Sulfonamides and trimethoprim Sulfones Sulfur Compounds
ATC-Code	G01AE10 J01EB04
CAS number	144-83-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Dihydropteroate synthase type-1	MLRSRVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDVGP...	unknown	inhibitor
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682