VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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22 entries where VIB is found as a standalone ligand

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	investigational nutraceutical vet_approved approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine Thiamine hydrochloride thiamine(1+) Thiamin thiamine(1+) ion Thiamine chloride Vitamin B1 Antiberiberi factor Aneurin thiaminium Thiamine mononitrate Tiamina Thiaminum
Brand Names	B-complex 100 Vitafer - Liq B 50 Capsules Ellis Tonic Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Multra With Iron Multi Spectrum - Tablet Davimet-M Multi Flow Tablets Mor-vites Tab Mvc Poly-Vi-Flor B Complex 25mg Vitamin Supplement Supravite Pour Enfants Twin Ultra Liquid Grape Flavor Maxum Multi-vite Super Stress Mega B Plus 1000mg Vit C Tab Thrivite 19 PR Natal 400 ec Prometa Quflora Pediatric Azesco B-complex Tab B-plex 100 FolaGent DHA Multiple Vitamin Tab Nephrocaps-QT Super Pantoplex Vyqua Vitamine 110 Liq TL-Folate Nata Komplete Glyco Lite Ect Quflora FE Vitramyn Multi-phyto Capsules Prenate Star Iberet 500 Total Living Concepts Formula One - Tab Davimet with Fluoride Dayavite Multi Tabs Kanga Sport Vitamins B & C Plus Minerals Niva-Plus Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Prenatal and Post Partum Supplement OB Complete DHA Childrens Chewable Vitamins W Iron Vp-pnv-dha Childrens Chewable Multivitamins Cavan Alpha Folica-V Multiple Vitamins & Minerals Tablets Usana Megavitamin Tablets - Tab Fortistress Tab Materna-tab Focalgin 90 DHA Multi Vitamines - Liq Novel Vita Kanga-B Vitamin B Group + C Multi #2 Vigem 12 Liquid Palm Springs Multvit and Min Tab VitaPhil Aide Hill.vite Supravite Stress Avec Vit E Duet DHA 400 ec Formula B Virt-Nate Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Prenatal Plus Multivitamin Plus DHA MiniCaps M.V.I. Paediatric Stress Ctr Srt Vasula Tab Kanga-kid Vitamins & Iron Children's Chewable Multivitamin Complete With Minerals Vit B Complex Plus Vit C 550mg Kids Stuff With Iron Tablets One-A-day Advance Men's RenaPlex-D Megavites Tab Super Kids Chewable Multivitamin Multimineral (chewable Tablets) One Per Day Vitamin and Mineral Dietary Supplement Complexe B-75 Multi-Vitamin with Fluoride Stress B Complex With C, E & Iron Meplex T 750 Zeldana Polymine Avec Zinc Et Cuivre THIAMINE HYDROCHLORIDE injection, solution Magnum-75 Vitamin and Mineral Supplement Childrens Chewable Multiple Vitamins Plus Fe Stress Tab With Iron and Vitamin E Thiamine Hydrochloride Inj 100mg/ml Complete One-A-day - Tab Multi - N.T.O.x Formula - Tab hormaSAN forte Thiamine HCl Inj 100mg/ml Tricare Prenatal B Complex 50+ Caplet Trinatal Rx 1 Vc II Advanced B & T Formula M.V.I. Pediatric Distilpure Msm Flintstones W Extra C Tab Replavite Vitasure Formula O.C. Master Key Multi Vitamin Multi Mineral Formula 2 Livita Children Abavite Bugs Bunny Chew Multi Vit Plus Iron Vitamin B Complex + C 300mg Cap WesNatal DHA Complete Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Swical-energy-2 Multi Vitamin and Mineral vitamin M.V.I.-12 Prena1 Plus Thiamine Hydrochloride Injection, USP TriphroCaps Vitranol B Complex W C Forte Cap Multivitamin & Minerals (iron Free) Concept OB Omega-3 Rx Complete Prenatal Formula Tab CitraNatal Assure Stress Formula + Iron ahoSAN Maxine Vitamin and Mineral Supplement Multivitamins and Minerals for Men Virt-Pn C-force Multitol-M VP-Vite Rx Multi-Vitamin Fluoride and Iron Drops Stress B Capsules With Vitamin C Virt-Vite Plus Supravite Stress Avec Vit E Et Fer TL-Fluorivite NEONATAL Complete CitraNatal 90 DHA Folica BE B-50 Complex Paramettes Adults Multivit-liq Renate DHA Vitafol One Vol-Care Rx Vitamin B Compound W C Tab 500mg Vtb Vitamin and Mineral Supplement Neo-bex Injectable Protect Plus SO 60 Children Choice Multivitamin W Iron Chew Tab Multivitamin with 0.25 mg Fluoride Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Thiamine Relnate DHA Gestamine Comprimes Vitaphil DHA Thrivite Rx Vitamin B-Complex Swical-energy 3e Age Premium Prenatal - Tablets RE Prenatal Multivitamin with Iron Floriva Plus Multi II IV Vi Tab B Plus C 300mg Timed Release Timed Release B-complex 100 Vitamin B Complex 100 Tab RE FAC-x Appedrine Everyday Multiple Vitamins Neonatal Plus Vitamin Natalvirt 90dha HemeNatal OB One Tablet Daily Mens Formula OBTREX DHA Combo Pack Fizz Multivitamins for Kids W C Loz Prim - Royal P.M.T. Hi Potency Balanced B-100 Complex - Tab Multiple Vitamins Thiamine HCl Tab 25mg Thiamine Hydrochloride Formula F L W M.V.I. 12 Vita Vim Multivitamins and Minerals Tab Alertonic Nephron FA Doctor's Choice Brand for Men Nutri-Tab OB One A Day Advance Adults 50+ Neo Vites Tab Balanced B-100 Timed Release Super Multi Children's Chewable Multivitamin and Multimineral Multivitamin with Fluoride Folivane-Plus with Ascorbic Acid Precursors Pnv Ob DHA Multi 12 Injection Viamon Ampoules Et Comprimes RE Nata OB Supplement De Multivitamines Infusion Arome Fruits Rouges B Vitamin Compound With B12 Thunas Obstetrix DHA Combo Pack Sopalamine/3b Plus C L.C. Supplement Kids Stuff Tablets bioJET Natavite Neo-bex Timed Release B-complex 50 Vinacal Vit B1 Ctr Srt 100mg Tender Age Multi Vitamins Kenwood Liquid Supplement Chewable Children's Complete Multivitamins With Essential Minerals Lipotropic Ctr Active FE Foltabs Prenatal Plus DHA Pretrate Supravite C 1000 Tricare Prenatal DHA One With Folate Maxi 6 Liq TriStart DHA Vita-Pac Floravit - Syr Prenatal Vitogen B Stress C600 Multiple Vitamins Tab Reaphirm Plant Source DHA Surbex-500 With Zinc One A Day Advance Fem Cal M Tab SetonET-EC PNV-Select Dialyvite Supreme D Multi-Vit-Flor Dermamed Nutrition for troubled skin For Kids Only Chewable Multivitamins Pediatric Infuvite Multiple Vitamins Prenatal Plus Revival 1 Tab Prenatal Vitamin and Mineral Supplement Tab Totalvit Plus Multi-11 Trinatal GT Vita-vim - Tab HemeNatal OB plus DHA Thiamine HCL 100 mg Amladex Vital-D Rx Multi-Vitamin Fluoride Supravite Bouteille 250ml Multivitamins and Minerals for Young Men Vitamin B Complex Plus 300mg Vitamin C Mega-vim 75 With Beta-carotene - Tablets Xyzbac Neomultivite Poly-Vitamin with Fluoride PR Natal 430 ec Maximum Once A Day Poly-Vi-Flor with Iron Multiple Vitamins Plus Iron for Women B6 Plus Tab Nutrifer Plus Tablets Stress Formula Multivitamin Tablets USP Forty Plus Vitamin Supplement Multi-force for Adults Tab Multivitamins and Minerals - Complete Cavan Heme OB B-100 Vitamin Supplement Provida OB Orifer F Stress B-complex Plus Iron With Vitamins C&e Chewable Adult Multivitamins With Minerals Liqui B Complex Allbee C 800 Tab B-100 Complex Tablets Spectrum Performa Multivitamins and Minerals Tablets Multi Nt-OX M-Natal Plus Gynedyn Tab O-Cal Prenatal Vitamin tensioSAN Marnatal F Vitamin B1 100 mg Liqui Vita Garfield Chewable Multivits Plus Iron Tab B Complex 500 Tab Feminique W Iron and Calcium Tab Formula Gly K.L. Vitamin-mineral Prenatal Vitamin and Mineral Supplement Tendera-OB Vyo Cylate - Pwr Mega Vitaminerals Children's Vitamins W Iron Chewable New Chapter's D'adamo 4 Your Type Multiple for Type O C-B Complex Twin Ultra Liquid Orange Flavor Multi Rol Vigo Multivitamins Drops/lozenge Vitamin B1 Tab 100mg USP Duet DHA Balanced Orti B Prena1 Vitamines Et Mineraux Comprimes Lexazin PNV Ferrous Fumarate Docusate Folic Acid Multitam Opti-manganese + B1 + C Caplet PreGen DHA Pregvit Folic 5 Childrens Multiple Vit and Min Chew Tab Trinatal Ultra Bal-Care DHA Essential Men's Multi Master Formula H.W. Children's Chewable Multi Vit & Mineral Multivitamins and Multiminerals Formula Regular Tablet B Totum 500 C.R.T. X Multivitamin & Mineral Powder Mix Chewable Multivitamins Plus Iron Flintstones Multiple Vitamins Tab Viva CT Prenatal Deriton Vitaphil 90 DHA Insur-all Vitamin Supplement E.S.T. Complex Vitamin B Compound W Vit C 250mg Tab Extra P.N. Vitamin-mineral Drink Mix Formula Lf Cavan Folate OB Mega 13 Multivitamin Formula Xvite Hylavite Bewon Elixir 0.05mg/ml Maintain Multiple Vitamin & Minerals Children's Chewable Tab Kanga-V Multivitamins & Minerals Children's Chewable Multi-vitamin NataFort Fem Time Tab Dia-vite Hemocyte Plus PreferaOB plus DHA Poly-VI-sol Drops Chela-chromium 200 Super B Compound W 500mg Vit C 50 Plus Multiple Vitamins & Minerals Xyzbac G WesCap-C-DHA Multivitamines Et Mineraux Junior Regulier Senior Multi One Renate Vitamin B Complex 50 B-1 Caps 500mg Super Daily No 2 Multi-kid NataChew Se-Tan PLUS C-Nate DHA Davimet with Iron Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Allbee With Vitamin C Cap Childrens Chewable Vitamin Tab Tricare Prenatal 2-part Daily Prenatal Vitamin System Ultra Hr Zoo Chews Somarexin and C 1000 Nephrocaps Childrens Chewable Multivitamins W Iron Multi 1000 Innersource Tab Chromease Tab Ultimate OB DHA Paramettes Chewable Multivitamins Plus Iron One A Day Advance Adults 50 Plus Formula Fm Vitamins & Minerals Tab Poly-VI-flor Leritone Junior CompleteNate Chewable Revit Plus Cap Extra Once A Day Super Vitalex Ampoule Buvable Thiamine HCl 100mg W C 20mg Multiple Vitamins With Minerals Tablets B-plus - Tab Maltlevol 12 Liq Hemarexin Tab Neonatal Vitamin Omnivex PNV Prenatal Vitamin Plus Vitamin A Focalgin CA PureFe Plus Children Choice Multivit Chewable Tab NESTABS Prenatal Multi-vitamin/Mineral Supplement Se-Natal 19 Chewable Thiamine HCl Injection - Liq 100mg/ml WestGel DHA Sopalamine 3b Plus vitaMedMD One Rx PROTECT IRON Liquid Rocky Mountain Multiple Vit and Min Mega Tab WesNate DHA Hormodausse Plus Calc Et D Tab Multivitamins and Minerals for Young Women Concept DHA THIAMINE HCl Stress Forte Plus Lipotropic Factors PNV Tabs 29-1 Junior Multi Vitamins - Regular Multinate DHA Extra MI-Vite RX Prenatabs FA Multi-force for Women Tab Vitamin B + C Cap Super Vita-vim With Beta-carotene - Tab Zalvit Multivitamins for Children Essential B Tablets B-complex Tablets Prenatal Supplement - Tab RenaPlex Vitrexate Multi Vite Liq Adult Escavite D Megavite Rx PM Caps Sopalamine/3b Tab Thiamine Hydrochloride Inj 100mg/ml USP Vitamin B Complex Plus C 300mg Timed Release Q.T. #4 Vitamin and Mineral Dietary Supplement Stress Formula Tini-cal Ampoules Childrens Chewable Multiple Vitamins W.iron Multi-Vitamin With Fluoride Multinate DHA Virt-Caps Revit Tab Vit-HA Multi Vitamin and Zinc Supplement Pregvit Folic 4 Vitamin B Cpd W Vit C Tab Multi Vitamin, Iron and Fluoride Tricare Prenatal Quick Dissolve Vitogen B Stress C Vit E Zinc & Cop Cavan Folate DHA Neonatal19 Zoo Chews Plus Iron Folika-NC Liqui B Complex Plus Oncovite Phytoplex B Liq Multivitamin & Multimineral G.A.S. Complex Paire OB Plus DHA Balanced B-50 B-complex Vitamins Tab CitraNatal Essence Twin Ultra Liquid Lemon-lime Flavor FolaMed DHA Select OB B1 400mg Ctr Tab Vita B Complex Tab Choice OB DHA Men's Dialyvite 5000 Lysamine Diet Supp Amp-tab C. Vit-min Formula Grand Master Formula Tab Original Bioscal Forte Multi-vitamin Supplement Capsules Bewon Elixir Mega Balance SetonET Balanced B-50 Complex Multivitamins and Minerals Tablets Nutrol-B-complex Harvest Of Values All B Complex Tab Prenatvite Vitazyme Acti-MN + B1 + C Caplet Timed Release Vita-vim Srt Chela Potassium Plus Prenatal Plus Iron Prenatal Vitamins Plus Folet DHA DuetDHA Balanced Gtf-vitamin-minerals & Pancreatin Tab Vita Balance 2000 Soluvit N NephPlex Rx Am Caps Vitamin B1 Complete Natal DHA B Complex 50 Vitamin Cap DaVITE Isotonix Multitech Vitamin Mineral Supplemen Multra Plex Essential Vitamins and Minerals Children's Chewable With Iron Time Release B 100 Compound - Tablet Prenatal Vitamin and Mineral Supplement -tab PreNatal 19 Multi-actin Revitex Ampoules Et Comprimes Ventrixyl Fe Select-OB Plus DHA Prenatal Supplement Plus DHA Vol-Plus Sun-rype Vitaburst Poly-Vi-Sol Dialyvite 3000 PrePLUS B Virol Iron Polysaccharides Folic Acid DHA Cedevita Plus Vitamin Supplement Vital Be-100 Synergistic Manganese Cap Kindervites Stress Formula Tab Natal PNV Luna Vitamin and Mineral Bar for Women Multi Vitamin & Minerals Allbee With C 550 Cap Complete Multivitamins and Minerals for Children healthy mamaBE WELL ROUNDED BE WELL ROUNDED Multi Vitamin - Mineral Pregvit Prenatvite Plus Childrens Chewable Tab Vitamin B Complex 100 Hylazinc PNV-First Provida DHA Adult Infuvite Multiple Vitamins Corvita B C Antistress Cap MultiVitamin with Fluoride Drops Hi Potency B Complex W Chelated Minerals Nitro Vites - Tab Zavitrol Milltrium Senior Vitamin and Mineral Supplement Gesticare DHA Multipack II Virt-Bal DHA Plus Vitamin B Compound Tab Quflora Pediatric Drops Cda-21 Vitamins With Non-medicinal Probiotic Complex Multi-vitamins With Minerals Prenatal Vitamins and Minerals Tablets Vita-worth B-complex Tablets Swiss One Timed Release Tab Kimchi Vitamin chewable multivitamin Vitranol Fe Multivitamines Multi B Vitamin B Complex W C 300mg Tab Omniquin One A Day Tab B Complex With C 300mg Low Potency B Complex Tab Se-Care Conceive Multivitamine Vitaflex Dietary Suplement Vitamine B1 Tab 100mg USP Triveen-Duo DHA Complex 5 - Pwr Natal-V RX Multi-vitamin/Multi-mineral Twin Opti Pwr Children's Chewable Multiple Vitamins (chewable Tablets) Multi Vitamin Drops with Fluoride with Iron Multivitamins W Iron Hi Potency Multi Tab Vitamin B1 Tab 100mg Children's Chew Multi & Min Tab Infant Multivitamin Drops B Complex W Vitamin C Fortis Cap Vitrexate FE D'pantothenic Acid-B1-B2 Tab vitaMedMD Rx Plus Vitamine B1 100 Mg - Tablet Prenara Animal Shapes Vita Vim With Beta Carotene-caplet Vitafol Ultra Zatean-Pn Chewable Multiple Vitamins Tab Thiamine HCl Tab 100mg Multi-vitamins Jenliva Active OB Multivitamines Plus Fer Pour Enfants (chewable Tablets) Derma-force Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vita Day Tab Vitamin & Mineral Formula 1 Dietary Supplement Liquid B Complex 50 Stress Vitamin B With C Complex Tablets Everyday Multiple Vitamins With Iron Complete-RF Prenatal Manganese 50mg Plus B1 & E Tab B Complex With C 300mg Tab Vitalife - Capsule Multivit with Fluoride Vege 1 Daily Tab Cc II PureFe OB Plus Numark Multivitamins Complete Multivitamins and Minerals Tablets Timed Release Prefera OB plus DHA Vitamin B Complex + C 600mg Tab Virt Nate Strovite One Caplets Card-floe II Tab Duet DHA Nutri-Tab OB plus DHA Acti-thiamine Caplet 100mg Paramettes Multivits Plus Iron Tab (teens) Mangadyn RayaVit Stress Tablets Orange Flavored Crystal Chews Tab Multi Plex I - Tab B-50 Hi Potency B Vitamins Tab Livron Plus Tab PR Natal 400 V & M Vitamin and Mineral Supplement Vitamin B1 Tablets 100mg Prevital Tab Escavite Lq L-Methyl PNV DHA Ferra Naka Plus Vitamins Revitalize Multi-vitamin and Mineral Complex Multi-12/k1 Pediatric Vitamine Du Groupe B Plus Fer - Liq Complex-75 Vit B Complex Ctr Flintstones Multiple Vitamins Plus Iron Ziphex Biovim Tab B-complex With Vitamin C, Biotin, Folic Acid Irospan 24/6 Toni Com Liq Vol-Nate B Complex With C 550mg B-100 Caps MVC-Fluoride Premium Prenatal Bacmin Foltabs Prenatal Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Hi Potency B52 B Complex Tab Stress B Complex With C, E and Iron Tab Tricare Prenatal DHA One Rx Multivitamin Synergistic Manganese Capsules Alsimine W Vitamins A D Vitabanks Vitamin Tab Preplus Bev B-150 Multi Vitamin-mineral Formula Bev 29 Tab B-Combo NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Pnv-VP-U Venexa FE Chewable Multiple Vitamins Plus Extra C Multi-Vitamin Drops with Fluoride and Iron Prenatryl Multiple Vitamins and Minerals Tab Daily Balance Tab Beminal With C Fortis Cap Childrens Chewable Vitamins CitraNatal Rx Gtf Support Caplet Multiple Vitamins and Minerals Capsules Multi Vitamin Plus Iron Pro Hers Vanilla B50 B Complex Tab Childrens Chewab Vitamin W Chel Minerals Elite OB Prenatal Multivitamin Sibergin B - Cap Stress B & C Caplet Se-Natal 19 Glyco-aide Tab Multi-Vit with Fluoride and Iron Infuvite Pediatric Maxi 10 Tab Multivitamines Pour Enfants (chewable Tablets) Prenate Elite Vitaplex Beminal With C Fortis Pws Multitabs Mega Capsules Folic-K B 6 Plus Obstetrix EC Materna - Tab Men's 50+ Multiple Vitamins W Iron Tab PNV Prenatal Plus Multivitamin Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Century Complete Virt Vite GT NeuroBion Women's Change Formula Se-Natal Osteo-force Complete Mega B Multiple Vitamins Childrens Chewable Balanced B-50 B-complex Vitamins, Timed Rele Cavan Prenatal Formula Gm OB Complete 400 Spectrum 2 Cap Super Charged Energy Corvite VIL-Rx Multi-Vitamin Edge OB Livron Plus Ampoule V-Natal Prenatal, DHA Fortamines 10 Capsules Chewable Multivitamins Great Day/am Formula Tab Complexe B 75mg NovaFerrum Multivitamin with Iron Pediatric Drops Olympian Multi Vit Plus Minerals Tab Swiss Total One Fortaplex Inj Supravite Stress Avec Vit E Cuivre Et Zinc Body Rox Multi Enfants Tab One-A-day Advance Fem - Tablets Stress Formula Vit B With C Complex Stress Formula B-comp + 500mg Vit C Tab Stress Tab With Zinc, Copper and Vitamin E Diaplex PreNatal Vitamins Plus High Potency Vitamin B Complex + C Tab Poly-Vite/Iron Oral Solution Vitamines Et Mineraux Enfants 970 Chewable Multiple Vitamins Plus Iron Tab Genicin Vita-S Strovite Forte Caplet Twin G.F. Powder Cavan-EC SOD DHA Carbassist Tablets Escavite Zyvit Vitachrom Gc Zintrexyl-C B50 Complex Integra Plus MultiVitamin Drops with Fluoride and Iron Stresstabs + Zinc-copper Multi-Vit with Fluoride Multi-vitamin Dietary Supplement Stress B Complex With C,e, Zinc and Copper Virt-Advance Viva Kids - Tab Onccor Children's Chewable Multiple Vit.plus Iron Beminal Fortis Elx Children's Chewable Multivitamins and Minerals B-plex Dialyvite Daily Energy Brand B-complex Penta-thion Pwr TL-Care DHA Chela-manganese 50 Plus Multiple Vitamins With Iron Stressmates Tricare Prenatal Compleat Nutra-clear Vita-amine Cap 100mg NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Adeks - Dps Neo Bex Elixir Vitafol Plus Natalvirt Ca Chewable Multiple Vitamins for Children Multi-12 Pediatric Multiple Vitamins W Minerals Tab Children's Chewable Multi Vit W Iron Natural Source Spectrum With Beta Carotene Taron-C DHA Permathene-12 - Caplet Tonicol Et A-D-C Ampoules/comprimes Folitin-Z Wellness Formula Complexe B Compose 75 Multiple Vitamins Plus Iron - Tab Floradix Formula Liq Lorid Puralor B-complex 50 Corvite Free Fortamines-10 Comprimes MultiVitamin with Fluoride Nutra-Z Genicin Vita-Q Pregnancy Multivitamin PreTAB Vitaday Tab PreferaOB Multivit Et Fer Ampoules Et Comprimes Vena-Bal DHA Virt-PN Vitamin B-1 Thiamine HCl 100mg Duet DHA 400 Vitamin B1 Tab 2mg USP P.N. Vitamin-mineral Drink Twin Ultra Liquid Fruit Punch Flavor Folika-V B Plus C 300 mg Tonimol Cap Liq Betaxin Liq 100mg/ml Renal Caps Dialysis/Stress Vitamin Supplement Virt-C DHA Children's Chewable Vit and Min Tab Ultra Enerforce MultiVitamin, Iron and Fluoride Drops Multivitamin Balanced B100 Women's Biomultiple Vitamin and Mineral Supplement Venexa Vita-vim With Beta-carotene - Tab Surbex 500 Filmtab Potassium Plus Vit B Complex Nutra Boost Balanced B50 Complex B-complex Liqui Infant Vitamins Vitamines Et Mineraux Women's Formula TRONVite Prenatal Vi-min Vasodyn Tab Vinate AZ Children's Chewable Multiple Vitamins - Tab Garfield Chewable Multivitamins Tab For Kids Only Chewable Multivit. Plus Iron Vimeral Tab Vitamin B Tablets Vitafol Caplet Hi Potency Stress B Tension With C Multiple Vitamins Plus Iron Tab Vasculine Multi Vitamins & Minerals Vitaday Junior Tab Daily-Vite Multi Plex II - Tab Z Bec Tab Revit Multi-vitamins and Minerals Super-pote Vitamin Supplement Dexivite Infa Drops Multivitamins B Complex W Vit C W Non-med Yeast&liver Tab Prenatal Vitamins Plus Low Iron B Complex Plus C 300mg Tab Chew.multiple Vits.with Extra C for Children Kid's Choice Children's Chewable Vitamins - Tab B-100 Hi Potency B Vitamins Tab Neonatal DHA Infuvite Adult O-Cal FA multivitamin Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Vita Plex Tab Infantol Drops Hyporyl - Tab Multiple Vit Plus Iron Tab Phytovim Cap Balanced B-100 B-complex Vitamins Tab Phytofortis + Calcium A-D Multiple Vitamins - Tablet Stress Complex 600 Avec Vit E Cuivre Zinc B-50 Complex Tab Thiamine HCl Tab 50mg Hemarexin Amp Multi-vitamines Enfants Comprime Inatal Advance PreQue 10 Prenatol-M Ultimate Tab Tricare Prenatal DHA One Vp-heme Ob Formula Hh Multi Vitamin Drops with Fluoride Only One - Tablet Central-vite 18 Essential Folika-T Chela Iron Plus C,b Complex Somavit Brand Vitamins and Minerals Complex Folivane-OB P.N.P. Vitamin Drink Pregnancy Multivitamin Folic 5 Adult Formula 50+ Paramettes Chewable Multivits With Iron Tab Flintstones Multiple Vitamins Prenatrix Dothelle DHA Multiple Vitamins and Minerals Stress Formula Multi-B Comp + 500mg Vit C Cap Super Vita Vim Multivitamins and Minerals Reno Caps AzesChew Kaydia Patch Centratex Enrich Core Pack - Children Vitamin and Mineral Supplement Mvc 9 Plus 3 Inj Hemarexin Liquid and Drinkable Ampoules Beminal W C Fortis Inj Childrens Chew Multi Vitamin Tab Tandem OB INATAL Ultra Thiamine Hydrochloride Injection USP, 100mg/ml Vitrexyl plus Iron Keylosa Biovita Vitrexyl Dexifol Multivitamin with fluoride DuetDHA Complete Paramettes Syrup PNV Prenatal Vitamin Poly-Vite Pediatric Oral Solution Re Ob 90 DHA Stress B&c Tab Mebolic Vitamin B Complex W C Tab Multicaps Glyco Plus Ect Vege Swiss One Multivitamin W Chel Mins Tab Bugs Bunny and Friends Multiple Vitamins Childrens Chewable Multiple Vitamins OB Complete Prenatal Methaver Hypo Vites Tab Materna Formula Pro-B Multivitamin with 1.0 mg Fluoride Multivitamins and Minerals for Women Q.T. Vitamin and Mineral Drink Mix Gemvites Jr Tab Chewable Twin G.F. Powder Vanilla Flavor Pnv-OB-dha Vitafol OB Caplet Maltlevol Liq Stress B With 1000 Mg Vitamin C One A Day Multiple Vit W Minerals Children's Chewable Multi Vitamins Mega Plex III - Pck Mvc 9+4 Inj Croq-vit Pour Enfants Multiple Vitamins With Iron Tablets B-complex-50 Tab Nrg Plus Liq Balanced B 125 Srt Vitamin B Complex One Daily VITES Children's Chewable Multi-vitamin Complete With Minerals Lipo-B-C Tab Vitamin B Complex Suppl Spark Cap 24 Multivitamins + Minerals Trinaz Vp-heme Ob DHA Multivitamines Et Mineraux Medi Msm (methyl Sulfonyl Methane) Animal Shapes w/Iron Chewtabs P.R.O. Complex Vita-B Vitamin B1 100mg Tablet Multi Vite Liq Junior For Kids Only Chewable Multivitamins - Tab Phytopure Dynam Ampoule Et Tablet Dialyvite with Zinc Multi-Nate 30 B1 Tab 100mg Multi Vitamin Drops with Fluoride and Iron Men's Biomultiple Vitamin and Mineral Supplement Super Stress Capsules Nutrilite Double X Se-Natal One Se-Plete DHA Multiple Vitamin Plus Minerals Tab Swiss One Phosthenine Vitamines Et Fer (ampoules Buvable) Swiss One Multi Vit & Chel Min Tab Multi-Vitamin Fluoride Drops Efferlife Multivitamins and Minerals Fusion Plus Davimet Finazol B Compound 50mg Tab Stress B Complex With C and E Tab Stress Tab Timed Release B Complex 100 Srt TM-Vite RX Supravite 10ml Ampoule Lipovite Adeks Tablets Multi Vitamin and Fluoride Poly Vi Flor Chewable Tab Iron Folate Plus Quflora FE Pediatric Drops Neo-vites & Minerals Tab Ventrixyl Complete One A Day Tab Vol-Tab Rx NovaMV Multivitamin WesCaps FloraFol Enviroflex - Tab Right Choice A.M. Multi Formula - Caplet Surbex-500 With Iron Swiss One Multivitamin and Mineral Caplet Prenatvite Complete Pro His Mint Vitamin B Complex Tab Children's Chewable Multi Vitamins With Iron Tablets Vitamin and Mineral Supplement - Liq Vita B + C 500 Tab Livita Adults Fibrik Alkadrenergy Tablets Multisol Vitamin B-1 100 Mg Tablets Virt-Tabs Bal-Care DHA Antlerviron One Daily Vitamin and Mineral Dietary Supplement L.G.I.T. Vitafant Cedevita Sugar-free Vitamin Supplement Thiamiject Injection - Liq Im IV 100mg/ml Formula D.S. Multivitamins and Minerals With Betacarotene Tablets T.R.I. B-plex Src N.E.U. Complex Dexatran Avon Vitadvance Multi-kids Complete Childrens Chewable Multiple Vitamins Tab Kanga-kid Multi-vitamin & Mineral Multivitamins W Minerals Extra Strength Moms Choice Rx RE Nata Vitamines Pour Bebes Et Enfants Dexatrim Tablets Tandem Plus Virt-Nate DHA B With C 500 Cap Mini-B Tab Multivitamins Mega Plex IV - Pck B Complex W C and B12 Inj Multivitamin Drops with Fluoride Envirocomplex M.V.I. Adult Mycelized Childrens Multi-vitamin Liq For-2 High Potency Multivitamins & Minerals Caplets Children's Vitamins Chewable VitaXyme CitraNatal DHA Vita-Rx Diabetic Vitamin Chewable Multiple Vit Plus Iron for Children Geritol Liquid B Stress C + Iron & Vite Balanced B-complex Vit + Vit C&e Tab Children's Multivitamins With Iron Flinstones Multiple Plus Iron MultiVitamin with Fluoride Chewable Multi Vitamin with Fluoride Vita-B-75 Cap TriAdvance Vitafol Fe Plus Vitamin B1 100mg PureVit DualFe Plus Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Ply Vi Sol Chewable Tab Myhephron Dialysis and Stress Supplement OB Complete Petite B Complex Tablets Prenatal Plus Vitamins Floriva Children's Chewable Multivitamins With Minerals Foliflex Multi Pro Prenatal Mega Antioxidant Children's Multivitamins Ribotin-E WesTab Plus MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Beminal 500 Tab Dalivit Classic Swiss One 10 Multivitamin and Mineral Tab Iron, Vit & Min Supp PR Natal 430 Cyroplex Betaxin
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682