RCSB PDB: Search

1EDO \| pdb_00001edo	Download File View File

THE X-RAY STRUCTURE OF BETA-KETO ACYL CARRIER PROTEIN REDUCTASE FROM BRASSICA NAPUS COMPLEXED WITH NADP+

Fisher, M., Kroon, J.T., Martindale, W., Stuitje, A.R., Slabas, A.R., Rafferty, J.B.

(2000) Structure 8: 339-347

Released	2001-01-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Brassica napus
Macromolecule	BETA-KETO ACYL CARRIER PROTEIN REDUCTASE (protein)
Unique Ligands	NAP

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1R42 \| pdb_00001r42	Download File View File

Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)

Towler, P., Staker, B., Prasad, S.G., Menon, S., Ryan, D., Tang, J., Parsons, T., Fisher, M., Williams, D., Dales, N.A., Patane, M.A., Pantoliano, M.W.

(2004) J Biological Chem 279: 17996-18007

Released	2004-02-03
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	angiotensin I converting enzyme 2 (protein) disordered segment of collectrin homology domain (protein)
Unique Ligands	CL, NAG, ZN

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1R4L \| pdb_00001r4l	Download File View File

Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)

Towler, P., Staker, B., Prasad, S.G., Menon, S., Ryan, D., Tang, J., Parsons, T., Fisher, M., Williams, D., Dales, N.A., Patane, M.A., Pantoliano, M.W.

(2004) J Biological Chem 279: 17996-18007

Released	2004-02-03
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	angiotensin I converting enzyme 2 (protein) disordered segment of collectrin homology domain (protein)
Unique Ligands	CL, NAG, XX5, ZN

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1TX9 \| pdb_00001tx9	Download File View File

gpd prior to capsid assembly

Morais, M.C., Fisher, M., Kanamaru, K., Fane, B.A., Rossmann, M.G.

(2004) Mol Cell 15: 991-997

Released	2005-04-26
Method	X-RAY DIFFRACTION 3.31 Å
Organisms	Sinsheimervirus phiX174
Macromolecule	Scaffolding protein D (protein)

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2B5V \| pdb_00002b5v	Download File View File

Crystal structure of glucose dehydrogenase from Haloferax mediterranei

Britton, K.L., Baker, P.J., Fisher, M., Ruzheinikov, S., Gilmour, D.J., Bonete, M.-J., Ferrer, J., Pire, C., Esclapez, J., Rice, D.W.

(2006) Proc Natl Acad Sci U S A 103: 4846-4851

Released	2006-04-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Haloferax mediterranei
Macromolecule	glucose dehydrogenase (protein)
Unique Ligands	NAP

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2B5W \| pdb_00002b5w	Download File View File

Crystal structure of D38C glucose dehydrogenase mutant from Haloferax mediterranei

Britton, K.L., Baker, P.J., Fisher, M., Ruzheinikov, S., Gilmour, D.J., Bonete, M.-J., Ferrer, J., Pire, C., Esclapez, J., Rice, D.W.

(2006) Proc Natl Acad Sci U S A 103: 4846-4851

Released	2006-04-04
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Haloferax mediterranei
Macromolecule	glucose dehydrogenase (protein)
Unique Ligands	FLC, K, NAP, ZN

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2VWG \| pdb_00002vwg	Download File View File

Haloferax mediterranei glucose dehydrogenase in complex with NADP, Zn and gluconolactone.

Baker, P.J., Britton, K.L., Fisher, M., Esclapez, J., Pire, C., Bonete, M.J., Ferrer, J., Rice, D.W.

(2009) Proc Natl Acad Sci U S A 106: 779-784

Released	2009-01-13
Method	X-RAY DIFFRACTION 2 Å
Organisms	Haloferax mediterranei
Macromolecule	GLUCOSE DEHYDROGENASE (protein)
Unique Ligands	LGC, NAP, ZN

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2VWH \| pdb_00002vwh	Download File View File

Haloferax mediterranei glucose dehydrogenase in complex with NADP, Zn and glucose.

Baker, P.J., Britton, K.L., Fisher, M., Esclapez, J., Pire, C., Bonete, M.J., Ferrer, J., Rice, D.W.

(2009) Proc Natl Acad Sci U S A 106: 779-784

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Haloferax mediterranei
Macromolecule	GLUCOSE DEHYDROGENASE (protein)
Unique Ligands	BGC, NAP, ZN

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2VWP \| pdb_00002vwp	Download File View File

Haloferax mediterranei glucose dehydrogenase in complex with NADPH and Zn.

Baker, P.J., Britton, K.L., Fisher, M., Esclapez, J., Pire, C., Bonete, M.J., Ferrer, J., Rice, D.W.

(2009) Proc Natl Acad Sci U S A 106: 779-784

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Haloferax mediterranei
Macromolecule	GLUCOSE DEHYDROGENASE (protein)
Unique Ligands	NDP, ZN

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2VWQ \| pdb_00002vwq	Download File View File

Haloferax mediterranei glucose dehydrogenase in complex with NADP and Zn.

Baker, P.J., Britton, K.L., Fisher, M., Esclapez, J., Pire, C., Bonete, M.J., Ferrer, J., Rice, D.W.

(2009) Proc Natl Acad Sci U S A 106: 779-784

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Haloferax mediterranei
Macromolecule	GLUCOSE DEHYDROGENASE (protein)
Unique Ligands	NAP, ZN

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2WMQ \| pdb_00002wmq	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.48 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYQ

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2WMR \| pdb_00002wmr	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYR

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2WMS \| pdb_00002wms	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYS

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2WMT \| pdb_00002wmt	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYT

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2WMU \| pdb_00002wmu	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYU

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2WMV \| pdb_00002wmv	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.009 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYV

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2WMW \| pdb_00002wmw	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZYW

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2WMX \| pdb_00002wmx	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., Klair, S., Burns, S., Boxall, K., Cherry, M., Fisher, M., Westwood, I.M., Walton, M.I., McHardy, T., Cheung, K.-M.J., Van Montfort, R., Williams, D., Aherne, G.W., Garrett, M.D., Reader, J., Collins, I.

(2009) J Med Chem 52: 4810

Released	2009-07-28
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	ZY6

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2XEY \| pdb_00002xey	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., McHardy, T., Klair, S., Boxall, K., Fisher, M., Cherry, M., Allen, C.E., Addison, G.J., Ellard, J., Aherne, G.W., Westwood, I.M., van Montfort, R., Garrett, M.D., Reader, J.C., Collins, I.

(2010) Bioorg Med Chem Lett 20: 4045

Released	2010-06-30
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	YVQ

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2XEZ \| pdb_00002xez	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., McHardy, T., Klair, S., Boxall, K., Fisher, M., Cherry, M., Allen, C.E., Addison, G.J., Ellard, J., Aherne, G.W., Westwood, I.M., vanMontfort, R., Garrett, M.D., Reader, J.C., Collins, I.

(2010) Bioorg Med Chem Lett 20: 4045

Released	2010-07-07
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	EDO, XEZ

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2XF0 \| pdb_00002xf0	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Matthews, T.P., McHardy, T., Klair, S., Boxall, K., Fisher, M., Cherry, M., Allen, C.E., Addison, G.J., Ellard, J., Aherne, G.W., Westwood, I.M., van Montfort, R., Garrett, M.D., Reader, J.C., Collins, I.

(2010) Bioorg Med Chem Lett 20: 4045

Released	2010-06-30
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	4UB, EDO

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2YM3 \| pdb_00002ym3	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Reader, J.C., Matthews, T.P., Klair, S., Cheung, K.M.J., Scanlon, J., Proisy, N., Addison, G., Ellard, J., Piton, N., Taylor, S., Cherry, M., Fisher, M., Boxall, K., Burns, S., Walton, M.I., Westwood, I.M., Hayes, A., Eve, P., Valenti, M., Brandon, A.H., Box, G., vanMontfort, R.L.M., Williams, D.H., Aherne, G.W., Raynaud, F.I., Eccles, S.A., Garrett, M.D., Collins, I.

(2011) J Med Chem 54: 8328

Released	2012-01-11
Method	X-RAY DIFFRACTION 2.007 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	EDO, YM3

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2YM4 \| pdb_00002ym4	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Reader, J.C., Matthews, T.P., Klair, S., Cheung, K.M.J., Scanlon, J., Proisy, N., Addison, G., Ellard, J., Piton, N., Taylor, S., Cherry, M., Fisher, M., Boxall, K., Burns, S., Walton, M.I., Westwood, I.M., Hayes, A., Eve, P., Valenti, M., Brandon, A.H., Box, G., vanMontfort, R.L.M., Williams, D.H., Aherne, G.W., Raynaud, F.I., Eccles, S.A., Garrett, M.D., Collins, I.

(2011) J Med Chem 54: 8328

Released	2012-01-11
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	4YM, EDO

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2YM5 \| pdb_00002ym5	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Reader, J.C., Matthews, T.P., Klair, S., Cheung, K.M.J., Scanlon, J., Proisy, N., Addison, G., Ellard, J., Piton, N., Taylor, S., Cherry, M., Fisher, M., Boxall, K., Burns, S., Walton, M.I., Westwood, I.M., Hayes, A., Eve, P., Valenti, M., Brandon, A.H., Box, G., vanMontfort, R.L.M., Williams, D.H., Aherne, G.W., Raynaud, F.I., Eccles, S.A., Garrett, M.D., Collins, I.

(2011) J Med Chem 54: 8328

Released	2012-01-11
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	EDO, YM5

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2YM6 \| pdb_00002ym6	Download File View File

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Reader, J.C., Matthews, T.P., Klair, S., Cheung, K.M.J., Scanlon, J., Proisy, N., Addison, G., Ellard, J., Piton, N., Taylor, S., Cherry, M., Fisher, M., Boxall, K., Burns, S., Walton, M.I., Westwood, I.M., Hayes, A., Eve, P., Valenti, M., Brandon, A.H., Box, G., vanMontfort, R.L.M., Williams, D.H., Aherne, G.W., Raynaud, F.I., Eccles, S.A., Garrett, M.D., Collins, I.

(2011) J Med Chem 54: 8328

Released	2012-01-11
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE CHK1 (protein)
Unique Ligands	EDO, YM6

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1EDO | pdb_00001edo

1R42 | pdb_00001r42

1R4L | pdb_00001r4l

1TX9 | pdb_00001tx9

2B5V | pdb_00002b5v

2B5W | pdb_00002b5w

2VWG | pdb_00002vwg

2VWH | pdb_00002vwh

2VWP | pdb_00002vwp

2VWQ | pdb_00002vwq

2WMQ | pdb_00002wmq

2WMR | pdb_00002wmr

2WMS | pdb_00002wms

2WMT | pdb_00002wmt

2WMU | pdb_00002wmu

2WMV | pdb_00002wmv

2WMW | pdb_00002wmw

2WMX | pdb_00002wmx

2XEY | pdb_00002xey

2XEZ | pdb_00002xez

2XF0 | pdb_00002xf0

2YM3 | pdb_00002ym3

2YM4 | pdb_00002ym4

2YM5 | pdb_00002ym5

2YM6 | pdb_00002ym6