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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Crowther, R.A."

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Search Summary

This query matches 13 Structures.

Refinements

Structure Determination Methodology

experimental (13)

Scientific Name of Source Organism

	Homo sapiens (11)
	Hepatitis B virus (1)
	Mus musculus (1)

Taxonomy

	Eukaryota (12)
	Riboviria (1)

Experimental Method

	ELECTRON MICROSCOPY (12)
	X-RAY DIFFRACTION (1)

Polymer Entity Type

Protein (13)

Refinement Resolution (Å)

	2.0 - 2.5 (1)
	3.0 - 3.5 (9)
	3.5 - 4.0 (3)

Release Date

	1995 - 1999 (1)
	2015 - 2019 (10)
	2020 - 2024 (2)

Symmetry Type

	Asymmetric (8)
	Helical (4)
	Icosahedral (1)

SCOP Classification

All alpha proteins (1)

AllSelected

1 to 13 of 13 Structures

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1QGT \| pdb_00001qgt	Download File View File

HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)

Leslie, A.G.W., Wynne, S.A., Crowther, R.A.

(1999) Mol Cell 3: 771-780

Released	1999-06-25
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Hepatitis B virus
Macromolecule	PROTEIN (HBV CAPSID PROTEIN) (protein)

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5O3L \| pdb_00005o3l	Download File View File

Paired helical filament in Alzheimer's disease brain

Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.

(2017) Nature 547: 185-190

Released	2017-07-26
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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5O3O \| pdb_00005o3o	Download File View File

Pronase-treated paired helical filament in Alzheimer's disease brain

Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.

(2017) Nature 547: 185-190

Released	2017-07-26
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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5O3T \| pdb_00005o3t	Download File View File

Straight filament in Alzheimer's disease brain

Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.

(2017) Nature 547: 185-190

Released	2017-07-26
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6GX5 \| pdb_00006gx5	Download File View File

Narrow Pick Filament from Pick's disease brain

Falcon, B., Zhang, W., Murzin, A.G., Murshudov, G., Garringer, H.J., Vidal, R., Crowther, R.A., Ghetti, B., Scheres, S.H.W., Goedert, M.

(2018) Nature 561: 137-140

Released	2018-09-12
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6NWP \| pdb_00006nwp	Download File View File

Chronic traumatic encephalopathy Type I Tau filament

Falcon, B., Zivanov, J., Zhang, W., Murzin, A.G., Garringer, H.J., Vidal, R., Crowther, R.A., Newell, K.L., Ghetti, B., Goedert, M., Scheres, H.W.

(2019) Nature 568: 420-423

Released	2019-03-27
Method	ELECTRON MICROSCOPY 2.3 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6NWQ \| pdb_00006nwq	Download File View File

Chronic traumatic encephalopathy Type II Tau filament

Falcon, B., Zivanov, J., Zhang, W., Murzin, A.G., Garringer, H.J., Vidal, R., Crowther, R.A., Newell, K.L., Ghetti, B., Goedert, M., Scheres, H.W.

(2019) Nature 568: 420-423

Released	2019-03-27
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6QJH \| pdb_00006qjh	Download File View File

Cryo-EM structure of heparin-induced 2N4R tau snake filaments

Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.

(2019) Elife 8:

Released	2019-02-20
Method	ELECTRON MICROSCOPY 3.3 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6QJM \| pdb_00006qjm	Download File View File

Cryo-EM structure of heparin-induced 2N4R tau twister filaments

Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.

(2019) Elife 8:

Released	2019-02-27
Method	ELECTRON MICROSCOPY 3.3 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6QJP \| pdb_00006qjp	Download File View File

Cryo-EM structure of heparin-induced 2N4R tau jagged filaments

Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.

(2019) Elife 8:

Released	2019-02-20
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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6QJQ \| pdb_00006qjq	Download File View File

Cryo-EM structure of heparin-induced 2N3R tau filaments

Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.

(2019) Elife 8:

Released	2019-02-20
Method	ELECTRON MICROSCOPY 3.7 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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8Q92 \| pdb_00008q92	Download File View File

P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line

Schweighauser, M., Murzin, A.G., Macdonald, J., Lavenir, I., Crowther, R.A., Scheres, S.H.W., Goedert, M.

(2023) Acta Neuropathol Commun 11: 160-160

Released	2023-10-11
Method	ELECTRON MICROSCOPY 3.05 Å
Organisms	Homo sapiens
Macromolecule	Microtubule-associated protein tau (protein)

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8Q96 \| pdb_00008q96	Download File View File

P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line

Schweighauser, M., Murzin, A.G., Macdonald, J., Lavenir, I., Crowther, R.A., Scheres, S.H.W., Goedert, M.

(2023) Acta Neuropathol Commun 11: 160-160

Released	2023-10-11
Method	ELECTRON MICROSCOPY 3.09 Å
Organisms	Mus musculus
Macromolecule	Isoform Tau-E of Microtubule-associated protein tau (protein) Unknown protein (protein)

1 to 13 of 13 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1QGT | pdb_00001qgt

HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)

5O3L | pdb_00005o3l

Paired helical filament in Alzheimer's disease brain

5O3O | pdb_00005o3o

Pronase-treated paired helical filament in Alzheimer's disease brain

5O3T | pdb_00005o3t

Straight filament in Alzheimer's disease brain

6GX5 | pdb_00006gx5

Narrow Pick Filament from Pick's disease brain

6NWP | pdb_00006nwp

Chronic traumatic encephalopathy Type I Tau filament

6NWQ | pdb_00006nwq

Chronic traumatic encephalopathy Type II Tau filament

6QJH | pdb_00006qjh

Cryo-EM structure of heparin-induced 2N4R tau snake filaments

6QJM | pdb_00006qjm

Cryo-EM structure of heparin-induced 2N4R tau twister filaments

6QJP | pdb_00006qjp

Cryo-EM structure of heparin-induced 2N4R tau jagged filaments

6QJQ | pdb_00006qjq

Cryo-EM structure of heparin-induced 2N3R tau filaments

8Q92 | pdb_00008q92

P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line

8Q96 | pdb_00008q96

P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Symmetry Type

SCOP Classification

1QGT | pdb_00001qgt

5O3L | pdb_00005o3l

5O3O | pdb_00005o3o

5O3T | pdb_00005o3t

6GX5 | pdb_00006gx5

6NWP | pdb_00006nwp

6NWQ | pdb_00006nwq

6QJH | pdb_00006qjh

6QJM | pdb_00006qjm

6QJP | pdb_00006qjp

6QJQ | pdb_00006qjq

8Q92 | pdb_00008q92

8Q96 | pdb_00008q96