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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Graf, R."

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Search Summary

This query matches 3 Structures.

Refinements

Structure Determination Methodology

experimental (3)

Scientific Name of Source Organism

	Homo sapiens (2)
	Conus striatus (1)

Taxonomy

Eukaryota (3)

Experimental Method

	X-RAY DIFFRACTION (2)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (3)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (1)

Release Date

	2005 - 2009 (1)
	2010 - 2014 (2)

Enzyme Classification Name

Hydrolases (2)

Symmetry Type

Asymmetric (3)

SCOP Classification

	All alpha proteins (2)
	Artifacts (2)
	Small proteins (1)

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2CA7 \| pdb_00002ca7	Download File View File

Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization

Bayrhuber, M., Vijayan, V., Ferber, M., Graf, R., Korukottu, J., Imperial, J., Garrett, J.E., Olivera, B.M., Terlau, H., Zweckstetter, M., Becker, S.

(2005) J Biological Chem 280: 23766-23770

Released	2006-01-05
Method	SOLUTION NMR
Organisms	Conus striatus
Macromolecule	CONKUNITZIN-S1 (protein)

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3SNI \| pdb_00003sni	Download File View File

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors

Malamas, M.S., Ni, Y., Erdei, J., Stange, H., Schindler, R., Lankau, H.-J., Grunwald, C., Fan, K.Y., Parris, K.D., Langen, B., Egerland, U., Hage, T., Marquis, K.L., Grauer, S., Brennan, J., Navarra, R., Graf, R., Harrison, B.L., Robichaud, A., Kronbach, T., Pangalos, M., Hofgen, N., Brandon, N.J.

(2011) J Med Chem 54: 7621-7638

Released	2011-10-26
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	546, CL, MG, ZN

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3SNL \| pdb_00003snl	Download File View File

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors

(2011) J Med Chem 54: 7621-7638

Released	2011-10-26
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	548, MG, ZN

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

2CA7 | pdb_00002ca7

Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization

3SNI | pdb_00003sni

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors

3SNL | pdb_00003snl

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2CA7 | pdb_00002ca7

Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization

3SNI | pdb_00003sni

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors

3SNL | pdb_00003snl

Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors