RCSB PDB: Search

1D5B \| pdb_00001d5b	Download File View File

UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY

Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.

(2000) Biochemistry 39: 627-632

Released	2000-02-09
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	chimeric OXY-COPE catalytic ANTIBODY AZ-28 (HEAVY chain) (protein) chimeric OXY-COPE catalytic ANTIBODY AZ-28 (light chain) (protein)
Unique Ligands	CD

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1D5I \| pdb_00001d5i	Download File View File

UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY

Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.

(2000) Biochemistry 39: 627-632

Released	2000-02-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN) (protein) CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN) (protein)
Unique Ligands	CD

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1D6V \| pdb_00001d6v	Download File View File

CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION

Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.

(2000) Biochemistry 39: 627-632

Released	2000-02-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN) (protein) CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN) (protein)
Unique Ligands	CD, HOP

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1F82 \| pdb_00001f82	Download File View File

BOTULINUM NEUROTOXIN TYPE B CATALYTIC DOMAIN

Hanson, M.A., Stevens, R.C.

(2000) Nat Struct Biol 7: 687-692

Released	2000-08-16
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Clostridium botulinum
Macromolecule	BOTULINUM NEUROTOXIN TYPE B (protein)
Unique Ligands	ZN

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1MT5 \| pdb_00001mt5	Download File View File

CRYSTAL STRUCTURE OF FATTY ACID AMIDE HYDROLASE

Bracey, M.H., Hanson, M.A., Masuda, K.R., Stevens, R.C., Cravatt, B.F.

(2002) Science 298: 1793-1796

Released	2002-12-18
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Rattus norvegicus
Macromolecule	Fatty-acid amide hydrolase (protein)
Unique Ligands	MAY

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2RH1 \| pdb_00002rh1	Download File View File

High resolution crystal structure of human B2-adrenergic G protein-coupled receptor.

Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)

(2007) Science 318: 1258-1265

Released	2007-10-30
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	beta-2-adrenergic receptor/T4-lysozyme chimera (protein)
Unique Ligands	12P, ACM, BU1, CAU, CLR, PLM, SO4
Unique branched monosaccharides	GLC

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3D4S \| pdb_00003d4s	Download File View File

Cholesterol bound form of human beta2 adrenergic receptor.

Hanson, M.A., Cherezov, V., Roth, C.B., Griffith, M.T., Jaakola, V.-P., Chien, E.Y.T., Velasquez, J., Kuhn, P., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)

(2008) Structure 16: 897-905

Released	2008-06-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Beta-2 adrenergic receptor/T4-lysozyme chimera (protein)
Unique Ligands	CLR, OLC, TIM

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3EML \| pdb_00003eml	Download File View File

The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385.

Jaakola, V.-P., Griffith, M.T., Hanson, M.A., Cherezov, V., Chien, E.Y.T., Lane, J.R., Ijzerman, A.P., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)

(2008) Science 322: 1211-1217

Released	2008-10-14
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Human Adenosine A2A receptor/T4 lysozyme chimera (protein)
Unique Ligands	SO4, STE, ZMA

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3V2W \| pdb_00003v2w	Download File View File

Crystal Structure of a Lipid G protein-Coupled Receptor at 3.35A

Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C., Sanna, M.G., Han, G.W., Kuhn, P., Rosen, H., Stevens, R.C., GPCR Network (GPCR)

(2012) Science 335: 851-855

Released	2012-02-15
Method	X-RAY DIFFRACTION 3.35 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Sphingosine 1-phosphate receptor 1, Lysozyme chimera (protein)
Unique Ligands	ML5, NAG

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3V2Y \| pdb_00003v2y	Download File View File

Crystal Structure of a Lipid G protein-Coupled Receptor at 2.80A

Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C., Sanna, M.G., Han, G.W., Kuhn, P., Rosen, H., Stevens, R.C., GPCR Network (GPCR)

(2012) Science 335: 851-855

Released	2012-02-15
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Sphingosine 1-phosphate receptor 1, Lysozyme chimera (E.C.3.2.1.17) (protein)
Unique Ligands	ML5, NAG

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4Z34 \| pdb_00004z34	Download File View File

Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO9780307

Chrencik, J.E., Roth, C.B., Terakado, M., Kurata, H., Omi, R., Kihara, Y., Warshaviak, D., Nakade, S., Asmar-Rovira, G., Mileni, M., Mizuno, H., Griffith, M.T., Rodgers, C., Han, G.W., Velasquez, J., Chun, J., Stevens, R.C., Hanson, M.A., GPCR Network (GPCR)

(2015) Cell 161: 1633-1643

Released	2015-06-03
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	Lysophosphatidic acid receptor 1, Soluble cytochrome b562 (protein)
Unique Ligands	1WV, ON7

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4Z35 \| pdb_00004z35	Download File View File

Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-9910539

Chrencik, J.E., Roth, C.B., Terakado, M., Kurata, H., Omi, R., Kihara, Y., Warshaviak, D., Nakade, S., Asmar-Rovira, G., Mileni, M., Mizuno, H., Griffith, M.T., Rodgers, C., Han, G.W., Velasquez, J., Chun, J., Stevens, R.C., Hanson, M.A., GPCR Network (GPCR)

(2015) Cell 161: 1633-1643

Released	2015-06-03
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	Lysophosphatidic acid receptor 1,Soluble cytochrome b562 (protein)
Unique Ligands	1WV, ON9

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4Z36 \| pdb_00004z36	Download File View File

Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-3080573

Chrencik, J.E., Roth, C.B., Terakado, M., Kurata, H., Omi, R., Kihara, Y., Warshaviak, D., Nakade, S., Asmar-Rovira, G., Mileni, M., Mizuno, H., Griffith, M.T., Rodgers, C., Han, G.W., Velasquez, J., Chun, J., Stevens, R.C., Hanson, M.A., GPCR Network (GPCR)

(2015) Cell 161: 1633-1643

Released	2015-06-03
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	Lysophosphatidic acid receptor 1,Soluble cytochrome b562 (protein)
Unique Ligands	1WV, ON3

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5TGZ \| pdb_00005tgz	Download File View File

Crystal Structure of the Human Cannabinoid Receptor CB1

Hua, T., Vemuri, K., Pu, M., Qu, L., Han, G.W., Wu, Y., Zhao, S., Shui, W., Li, S., Korde, A., Laprairie, R.B., Stahl, E.L., Ho, J.H., Zvonok, N., Zhou, H., Kufareva, I., Wu, B., Zhao, Q., Hanson, M.A., Bohn, L.M., Makriyannis, A., Stevens, R.C., Liu, Z.J.

(2016) Cell 167: 750-762.e14

Released	2016-11-02
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1 (protein)
Unique Ligands	FMN, OLA, OLC, PEG, ZDG

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5V56 \| pdb_00005v56	Download File View File

2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114

Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.

(2017) Nat Commun 8: 15383-15383

Released	2017-05-24
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Smoothened homolog,Flavodoxin,Smoothened homolog (protein)
Unique Ligands	836, FMN, NAG

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5V57 \| pdb_00005v57	Download File View File

3.0A SYN structure of the multi-domain human smoothened receptor in complex with TC114

Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.

(2017) Nat Commun 8: 15383-15383

Released	2017-05-24
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Smoothened homolog,Flavodoxin,Smoothened homolog (protein)
Unique Ligands	836, FMN, OLC

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5VBL \| pdb_00005vbl	Download File View File

Structure of apelin receptor in complex with agonist peptide

Ma, Y., Yue, Y., Ma, Y., Zhang, Q., Zhou, Q., Song, Y., Shen, Y., Li, X., Ma, X., Li, C., Hanson, M.A., Han, G.W., Sickmier, E.A., Swaminath, G., Zhao, S., Stevems, R.C., Hu, L.A., Zhong, W., Zhang, M., Xu, F.

(2017) Structure 25: 858-866.e4

Released	2017-05-31
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Clostridium pasteurianum Homo sapiens
Macromolecule	Apelin receptor,Rubredoxin,Apelin receptor Chimera (protein) agonist peptide (protein)
Unique Ligands	OLC, ZN

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5VEW \| pdb_00005vew	Download File View File

Structure of the human GLP-1 receptor complex with PF-06372222

Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.

(2017) Nature 546: 312-315

Released	2017-05-24
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Glucagon-like peptide 1 receptor,Endolysin chimera (protein)
Unique Ligands	97Y, OLA, OLC

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5VEX \| pdb_00005vex	Download File View File

Structure of the human GLP-1 receptor complex with NNC0640

Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.

(2017) Nature 546: 312-315

Released	2017-05-17
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Glucagon-like peptide 1 receptor, Endolysin chimera (protein)
Unique Ligands	97V

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5WF5 \| pdb_00005wf5	Download File View File

Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution

White, K.L., Eddy, M.T., Gao, Z., Han, G.W., Hanson, M.A., Lian, T., Deary, A., Patel, N., Jacobson, K.A., Katritch, V., Stevens, R.C.

(2018) Structure 26: 259-269.e5

Released	2018-02-21
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Human A2a adenosine receptor T4L chimera (protein)
Unique Ligands	OLC, UKA

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5WF6 \| pdb_00005wf6	Download File View File

Agonist bound human A2a adenosine receptor with S91A mutation at 2.90 A resolution

White, K.L., Eddy, M.T., Gao, Z., Han, G.W., Hanson, M.A., Lian, T., Deary, A., Patel, N., Jacobson, K.A., Katritch, V., Stevens, R.C.

(2018) Structure 26: 259-269.e5

Released	2018-02-21
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	Human A2a adenosine receptor T4L chimera (protein)
Unique Ligands	OLC, UKA

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5XR8 \| pdb_00005xr8	Download File View File

Crystal structure of the human CB1 in complex with agonist AM841

Hua, T., Vemuri, K., Nikas, P.S., Laprairie, R.B., Wu, Y., Qu, L., Pu, M., Korde, A., Shan, J., Ho, J.H., Han, G.W., Ding, K., Li, X., Liu, H., Hanson, M.A., Zhao, S., Bohn, L.M., Makriyannis, A., Stevens, R.C., Liu, Z.J.

(2017) Nature 547: 468-471

Released	2017-07-12
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1 (protein)
Unique Ligands	8D0, CLR, FMN, PEG

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5XRA \| pdb_00005xra	Download File View File

Crystal structure of the human CB1 in complex with agonist AM11542

Hua, T., Vemuri, K., Nikas, P.S., Laprairie, R.B., Wu, Y., Qu, L., Pu, M., Korde, A., Shan, J., Ho, J.H., Han, G.W., Ding, K., Li, X., Liu, H., Hanson, M.A., Zhao, S., Bohn, L.M., Makriyannis, A., Stevens, R.C., Liu, Z.J.

(2017) Nature 547: 468-471

Released	2017-07-12
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1 (protein)
Unique Ligands	8D3, CLR, FMN, OLA, OLC, PEG

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6BQG \| pdb_00006bqg	Download File View File

Crystal structure of 5-HT2C in complex with ergotamine

Peng, Y., McCorvy, J.D., Harpsoe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajse, L.F., Huang, X.P., Wu, Y., Shen, L., Bjorn-Yoshimoto, W.E., Ding, K., Wacker, D., Han, G.W., Cheng, J., Katritch, V., Jensen, A.A., Hanson, M.A., Zhao, S., Gloriam, D.E., Roth, B.L., Stevens, R.C., Liu, Z.

(2018) Cell 172: 719-730.e14

Released	2018-02-14
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	5-hydroxytryptamine receptor 2C,Soluble cytochrome b562 (protein)
Unique Ligands	ERM, OLC

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6BQH \| pdb_00006bqh	Download File View File

Crystal structure of 5-HT2C in complex with ritanserin

Peng, Y., McCorvy, J.D., Harpsoe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajse, L.F., Huang, X.P., Wu, Y., Shen, L., Bjorn-Yoshimoto, W.E., Ding, K., Wacker, D., Han, G.W., Cheng, J., Katritch, V., Jensen, A.A., Hanson, M.A., Zhao, S., Gloriam, D.E., Roth, B.L., Stevens, R.C., Liu, Z.

(2018) Cell 172: 719-730.e14

Released	2018-02-14
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	5-hydroxytryptamine receptor 2C,Soluble cytochrome b562 (protein)
Unique Ligands	E2J, OLA, OLC, PEG

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1D5B | pdb_00001d5b

1D5I | pdb_00001d5i

1D6V | pdb_00001d6v

1F82 | pdb_00001f82

1MT5 | pdb_00001mt5

2RH1 | pdb_00002rh1

3D4S | pdb_00003d4s

3EML | pdb_00003eml

3V2W | pdb_00003v2w

3V2Y | pdb_00003v2y

4Z34 | pdb_00004z34

4Z35 | pdb_00004z35

4Z36 | pdb_00004z36

5TGZ | pdb_00005tgz

5V56 | pdb_00005v56

5V57 | pdb_00005v57

5VBL | pdb_00005vbl

5VEW | pdb_00005vew

5VEX | pdb_00005vex

5WF5 | pdb_00005wf5

5WF6 | pdb_00005wf6

5XR8 | pdb_00005xr8

5XRA | pdb_00005xra

6BQG | pdb_00006bqg

6BQH | pdb_00006bqh