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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Holak, T.A."

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Search Summary

This query matches 92 Structures.

Refinements

Structure Determination Methodology

experimental (92)

Scientific Name of Source Organism

	Homo sapiens (51)
	Dictyostelium discoideum (7)
	Drosophila melanogaster (5)
	Hirudo medicinalis (5)
	Bos taurus (3)
	Cucurbita maxima (3)
	Danio rerio (3)
	Mus musculus (3)
	cfp marker plasmid pWM1009 (3)
	synthetic construct (3)

More...

Taxonomy

	Eukaryota (77)
	Bacteria (11)
	other sequences (6)
	Eukaryota (eukaryotes) (4)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (68)
	SOLUTION NMR (24)

Polymer Entity Type

	Protein (92)
	DNA (1)

Refinement Resolution (Å)

	0.5 - 1.0 (1)
	1.0 - 1.5 (8)
	1.5 - 2.0 (22)
	2.0 - 2.5 (29)
	2.5 - 3.0 (8)

Release Date

	1990 - 1994 (6)
	1995 - 1999 (12)
	2000 - 2004 (13)
	2005 - 2009 (20)
	2010 - 2014 (19)
	2015 - 2019 (17)
	2020 - 2024 (5)

Enzyme Classification Name

	Transferases (15)
	Hydrolases (11)
	Ligases (12)
	Isomerases (1)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (75)
	Cyclic (19)
	Dihedral (2)

SCOP Classification

	All beta proteins (23)
	All alpha proteins (21)
	Artifacts (18)
	Small proteins (16)
	Alpha and beta proteins (a/b) (11)
	Alpha and beta proteins (a+b) (7)
	Peptides (2)

AllSelected

1 to 25 of 92 Structures

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1A23 \| pdb_00001a23	Download File View File

SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, MINIMIZED AVERAGE STRUCTURE

Schirra, H.J., Renner, C., Czisch, M., Huber-Wunderlich, M., Holak, T.A., Glockshuber, R.

(1998) Biochemistry 37: 6263-6276

Released	1998-09-16
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	DSBA (protein)

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1A24 \| pdb_00001a24	Download File View File

SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, FAMILY OF 20 STRUCTURES

Schirra, H.J., Renner, C., Czisch, M., Huber-Wunderlich, M., Holak, T.A., Glockshuber, R.

(1998) Biochemistry 37: 6263-6276

Released	1998-09-16
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	DSBA (protein)

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1AG4 \| pdb_00001ag4	Download File View File

NMR STRUCTURE OF SPHERULIN 3A (S3A) FROM PHYSARUM POLYCEPHALUM, MINIMIZED AVERAGE STRUCTURE

Rosinke, B., Renner, C., Mayr, E.-M., Jaenicke, R., Holak, T.A.

(1997) J Mol Biology 271: 645-655

Released	1998-04-08
Method	SOLUTION NMR
Organisms	Physarum polycephalum
Macromolecule	SPHERULIN 3A (protein)

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1BD8 \| pdb_00001bd8	Download File View File

STRUCTURE OF CDK INHIBITOR P19INK4D

Baumgartner, R., Fernandez-Catalan, C., Winoto, A., Huber, R., Engh, R., Holak, T.A.

(1998) Structure 6: 1279-1290

Released	1998-10-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	P19INK4D CDK4/6 INHIBITOR (protein)

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1CTI \| pdb_00001cti	Download File View File

DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING

Holak, T.A., Gondol, D., Otlewski, J., Wilusz, T.

(1989) J Mol Biology 210: 635-648

Released	1992-01-15
Method	SOLUTION NMR
Organisms	Cucurbita maxima
Macromolecule	TRYPSIN INHIBITOR (protein)

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1DNY \| pdb_00001dny	Download File View File

SOLUTION STRUCTURE OF PCP, A PROTOTYPE FOR THE PEPTIDYL CARRIER DOMAINS OF MODULAR PEPTIDE SYNTHETASES

Weber, T., Baumgartner, R., Renner, C., Marahiel, M.A., Holak, T.A.

(2000) Structure 8: 407-418

Released	2000-05-17
Method	SOLUTION NMR
Organisms	Brevibacillus brevis
Macromolecule	NON-RIBOSOMAL PEPTIDE SYNTHETASE PEPTIDYL CARRIER PROTEIN (protein)

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1DTD \| pdb_00001dtd	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2)

Reverter, D., Fernandez-Catalan, C., Bode, W., Holak, T.A., Aviles, F.X.

(2000) Nat Struct Biol 7: 322-328

Released	2000-07-12
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	CARBOXYPEPTIDASE A2 (protein) METALLOCARBOXYPEPTIDASE INHIBITOR (protein)
Unique Ligands	GLU, ZN

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1DTV \| pdb_00001dtv	Download File View File

NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI)

Reverter, D., Fernandez-Catalan, C., Bode, W., Holak, T.A., Aviles, F.X.

(2000) Nat Struct Biol 7: 322-328

Released	2000-07-19
Method	SOLUTION NMR
Organisms	Hirudo medicinalis
Macromolecule	CARBOXYPEPTIDASE INHIBITOR (protein)

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1GNC \| pdb_00001gnc	Download File View File

STRUCTURE AND DYNAMICS OF THE HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR DETERMINED BY NMR SPECTROSCOPY. LOOP MOBILITY IN A FOUR-HELIX-BUNDLE PROTEIN

Zink, T.W., Ross, A., Rudolph, R., Holak, T.A.

(1994) Biochemistry 33: 8453-8463

Released	1994-07-31
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	GRANULOCYTE COLONY-STIMULATING FACTOR (protein)

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1H59 \| pdb_00001h59	Download File View File

Complex of IGFBP-5 with IGF-I

Zeslawski, W., Beisel, H.G., Kamionka, M., Kalus, W., Engh, R.A., Huber, R., Holak, T.A.

(2001) EMBO J 20: 3638

Released	2002-05-16
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5 (protein) INSULIN-LIKE GROWTH FACTOR IA (protein)

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1HCD \| pdb_00001hcd	Download File View File

STRUCTURE OF HISACTOPHILIN IS SIMILAR TO INTERLEUKIN-1 BETA AND FIBROBLAST GROWTH FACTOR

Habazettl, J., Gondol, D., Wiltscheck, R., Otlewski, J., Schleicher, M., Holak, T.A.

(1992) Nature 359: 855-858

Released	1994-10-15
Method	SOLUTION NMR
Organisms	Dictyostelium discoideum
Macromolecule	HISACTOPHILIN (protein)

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1HCE \| pdb_00001hce	Download File View File

STRUCTURE OF HISACTOPHILIN IS SIMILAR TO INTERLEUKIN-1 BETA AND FIBROBLAST GROWTH FACTOR

Habazettl, J., Gondol, D., Wiltscheck, R., Otlewski, J., Schleicher, M., Holak, T.A.

(1992) Nature 359: 855-858

Released	1994-09-30
Method	SOLUTION NMR
Organisms	Dictyostelium discoideum
Macromolecule	HISACTOPHILIN (protein)

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1HJ0 \| pdb_00001hj0	Download File View File

Thymosin beta9

Stoll, R., Voelter, W., Holak, T.A.

(1997) Biopolymers 41: 623

Released	2002-01-04
Method	SOLUTION NMR
Organisms	Bos taurus
Macromolecule	THYMOSIN BETA9 (protein)

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1HJD \| pdb_00001hjd	Download File View File

Melanoma inhibitory activity (MIA) protein

Stoll, R., Voelter, W., Bosserhoff, A.K., Holak, T.A.

(2001) EMBO J 20: 340

Released	2002-01-29
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	HUMAN MELANOMA INHIBITORY ACTIVITY PROTEIN (protein)

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1I16 \| pdb_00001i16	Download File View File

STRUCTURE OF INTERLEUKIN 16: IMPLICATIONS FOR FUNCTION, NMR, 20 STRUCTURES

Muehlhahn, P., Zweckstetter, M., Georgescu, J., Ciosto, C., Renner, C., Lanzendoerfer, M., Lang, K., Ambrosius, D., Baier, M., Kurth, R., Holak, T.A.

(1998) Nat Struct Biol 5: 682-686

Released	1999-05-25
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	INTERLEUKIN 16 (protein)

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1KSR \| pdb_00001ksr	Download File View File

THE REPEATING SEGMENTS OF THE F-ACTIN CROSS-LINKING GELATION FACTOR (ABP-120) HAVE AN IMMUNOGLOBULIN FOLD, NMR, 20 STRUCTURES

Fucini, P., Renner, C., Herberhold, C., Noegel, A.A., Holak, T.A.

(1997) Nat Struct Biol 4: 223-230

Released	1997-08-20
Method	SOLUTION NMR
Organisms	Dictyostelium discoideum
Macromolecule	GELATION FACTOR (protein)

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1NMF \| pdb_00001nmf	Download File View File

MAJOR COLD-SHOCK PROTEIN, NMR, 20 STRUCTURES

Schnuchel, A., Holak, T.A.

(1993) Nature 364: 169-171

Released	1996-07-11
Method	SOLUTION NMR
Organisms	Bacillus subtilis
Macromolecule	MAJOR COLD-SHOCK PROTEIN (protein)

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1NMG \| pdb_00001nmg	Download File View File

MAJOR COLD-SHOCK PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE

Schnuchel, A., Holak, T.A.

(1993) Nature 364: 169-171

Released	1996-07-11
Method	SOLUTION NMR
Organisms	Bacillus subtilis
Macromolecule	MAJOR COLD-SHOCK PROTEIN (protein)

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1NPS \| pdb_00001nps	Download File View File

CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S

Wenk, M., Baumgartner, R., Mayer, E.M., Huber, R., Holak, T.A., Jaenicke, R.

(1999) J Mol Biology 286: 1533-1545

Released	2000-02-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Myxococcus xanthus
Macromolecule	DEVELOPMENT-SPECIFIC PROTEIN S (protein)
Unique Ligands	CA

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1OH1 \| pdb_00001oh1	Download File View File

Solution structure of staphostatin A form Staphylococcus aureus confirms the discovery of a novel class of cysteine proteinase inhibitors.

Dubin, G., Popowicz, G., Krajewski, M., Stec, J., Bochtler, M., Potempa, J., Dubin, A., Holak, T.A.

(2003) Biochemistry 42: 13449

Released	2003-11-20
Method	SOLUTION NMR
Organisms	Staphylococcus aureus
Macromolecule	STAPHOSTATIN A (protein)

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1OXD \| pdb_00001oxd	Download File View File

Expansion of the Genetic Code Enables Design of a Novel "Gold" Class of Green Fluorescent Proteins

Hyun Bae, J., Rubini, M., Jung, G., Wiegand, G., Seifert, M.H., Azim, M.K., Kim, J.S., Zumbusch, A., Holak, T.A., Moroder, L., Huber, R., Budisa, N.

(2003) J Mol Biology 328: 1071-1081

Released	2003-12-02
Method	X-RAY DIFFRACTION 1.15 Å
Organisms	cfp marker plasmid pWM1009
Macromolecule	cyan fluorescent protein cfp (protein)

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1OXE \| pdb_00001oxe	Download File View File

Expansion of the Genetic Code Enables Design of a Novel "Gold" Class of Green Fluorescent Proteins

Hyun Bae, J., Rubini, M., Jung, G., Wiegand, G., Seifert, M.H., Azim, M.K., Kim, J.S., Zumbusch, A., Holak, T.A., Moroder, L., Huber, R., Budisa, N.

(2003) J Mol Biology 328: 1071-1081

Released	2003-12-02
Method	X-RAY DIFFRACTION 1.15 Å
Organisms	cfp marker plasmid pWM1009
Macromolecule	cyan fluorescent protein cfp (protein)

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1OXF \| pdb_00001oxf	Download File View File

Expansion of the Genetic Code Enables Design of a Novel "Gold" Class of Green Fluorescent Proteins

Hyun Bae, J., Rubini, M., Jung, G., Wiegand, G., Seifert, M.H., Azim, M.K., Kim, J.S., Zumbusch, A., Holak, T.A., Moroder, L., Huber, R., Budisa, N.

(2003) J Mol Biology 328: 1071-1081

Released	2003-12-02
Method	X-RAY DIFFRACTION 1.69 Å
Organisms	cfp marker plasmid pWM1009
Macromolecule	cyan fluorescent protein cfp (protein)

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1QLO \| pdb_00001qlo	Download File View File

Structure of the active domain of the herpes simplex virus protein ICP47 in water/sodium dodecyl sulfate solution determined by nuclear magnetic resonance spectroscopy

Pfaender, R., Neumann, L., Zweckstetter, M., Seger, C., Holak, T.A., Tampe, R.

(1999) Biochemistry 38: 13692

Released	1999-12-14
Method	SOLUTION NMR
Organisms	Human alphaherpesvirus 1 strain 17
Macromolecule	HERPES SIMPLEX VIRUS PROTEIN ICP47 (protein)

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1S0P \| pdb_00001s0p	Download File View File

Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.

Ksiazek, D., Brandstetter, H., Israel, L., Bourenkov, G.P., Katchalova, G., Janssen, K.P., Bartunik, H.D., Noegel, A.A., Schleicher, M., Holak, T.A.

(2003) Structure 11: 1171-1178

Released	2004-01-27
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Dictyostelium discoideum
Macromolecule	Adenylyl cyclase-associated protein (protein)
Unique Ligands	MG

1 to 25 of 92 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1A23 | pdb_00001a23

1A24 | pdb_00001a24

1AG4 | pdb_00001ag4

1BD8 | pdb_00001bd8

1CTI | pdb_00001cti

1DNY | pdb_00001dny

1DTD | pdb_00001dtd

1DTV | pdb_00001dtv

1GNC | pdb_00001gnc

1H59 | pdb_00001h59

1HCD | pdb_00001hcd

1HCE | pdb_00001hce

1HJ0 | pdb_00001hj0

1HJD | pdb_00001hjd

1I16 | pdb_00001i16

1KSR | pdb_00001ksr

1NMF | pdb_00001nmf

1NMG | pdb_00001nmg

1NPS | pdb_00001nps

1OH1 | pdb_00001oh1

1OXD | pdb_00001oxd

1OXE | pdb_00001oxe

1OXF | pdb_00001oxf

1QLO | pdb_00001qlo

1S0P | pdb_00001s0p