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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Hou, J."

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Search Summary

This query matches 52 Structures.

Refinements

Structure Determination Methodology

experimental (52)

Scientific Name of Source Organism

	Homo sapiens (17)
	Vibrio cholerae O1 biovar El Tor str. N16961 (16)
	Bacillus anthracis (3)
	Vibrio cholerae MJ-1236 (3)
	Bacillus anthracis str. Sterne (2)
	Escherichia coli CFT073 (2)
	Helicobacter pylori 26695 (2)
	Bacillus anthracis str. 'Ames Ancestor (1)
	Deinagkistrodon acutus (1)
	Listeria monocytogenes EGD-e (1)

More...

Taxonomy

	Bacteria (34)
	Eukaryota (18)

Experimental Method

X-RAY DIFFRACTION (52)

Polymer Entity Type

Protein (52)

Refinement Resolution (Å)

	1.0 - 1.5 (4)
	1.5 - 2.0 (18)
	2.0 - 2.5 (20)
	2.5 - 3.0 (10)

Release Date

	2005 - 2009 (11)
	2010 - 2014 (33)
	2015 - 2019 (8)

Enzyme Classification Name

	Oxidoreductases (20)
	Hydrolases (16)
	Transferases (11)

Symmetry Type

	Cyclic (20)
	Asymmetric (14)
	Dihedral (18)

SCOP Classification

	Alpha and beta proteins (a/b) (21)
	Artifacts (19)
	All alpha proteins (14)
	Multi-domain proteins (alpha and beta) (2)
	All beta proteins (2)
	Alpha and beta proteins (a+b) (1)

AllSelected

1 to 25 of 52 Structures

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1YP1 \| pdb_00001yp1	Download File View File

Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase from venom of Agkistrodon acutus

Lou, Z., Hou, J., Chen, J., Liang, X., Qiu, P., Liu, Y., Li, M., Rao, Z.

(2005) J Struct Biol 152: 195-203

Released	2006-01-17
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Deinagkistrodon acutus
Macromolecule	FII (protein) KNL (protein)
Unique Ligands	ZN

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2OUN \| pdb_00002oun	Download File View File

crystal structure of PDE10A2 in complex with AMP

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H., Ke, H.M.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	AMP, MG, ZN

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2OUP \| pdb_00002oup	Download File View File

crystal structure of PDE10A

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	MG, ZN

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2OUQ \| pdb_00002ouq	Download File View File

crystal structure of PDE10A2 in complex with GMP

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	5GP, MG, ZN

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2OUR \| pdb_00002our	Download File View File

crystal structure of PDE10A2 mutant D674A in complex with cAMP

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	CMP, MG

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2OUS \| pdb_00002ous	Download File View File

crystal structure of PDE10A2 mutant D674A

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	MG

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2OUU \| pdb_00002ouu	Download File View File

crystal structure of PDE10A2 mutant D674A in complex with cGMP

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.52 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	35G, MG

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2OUV \| pdb_00002ouv	Download File View File

crystal structure of pde10a2 mutant of D564N

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	MG, ZN

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2OUY \| pdb_00002ouy	Download File View File

crystal structure of pde10a2 mutant D564A in complex with cAMP.

Wang, H.C., Liu, Y.D., Hou, J., Zheng, M.Y., Robinson, H.

(2007) Proc Natl Acad Sci U S A 104: 5782-5787

Released	2007-03-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (protein)
Unique Ligands	CMP, MG, ZN

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3ICC \| pdb_00003icc	Download File View File

Crystal structure of a putative 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis at 1.87 A resolution

Hou, J., Chruszcz, M., Zheng, H., Cymborowski, M., Luo, H.-B., Skarina, T., Gordon, S., Savchenko, A., Edwards, A.M., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2012) Acta Crystallogr Sect F Struct Biol Cryst Commun 68: 632-637

Released	2009-07-28
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Bacillus anthracis str. 'Ames Ancestor
Macromolecule	Putative 3-oxoacyl-(acyl carrier protein) reductase (protein)
Unique Ligands	CL, MES, NAP, SO4

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3K3E \| pdb_00003k3e	Download File View File

Crystal structure of the PDE9A catalytic domain in complex with (R)-BAY73-6691

Wang, H., Luo, X., Ye, M., Hou, J., Robinson, H., Ke, H.

(2010) J Med Chem 53: 1726-1731

Released	2010-02-16
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (protein)
Unique Ligands	MG, PDB, ZN

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3K3H \| pdb_00003k3h	Download File View File

Crystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-6691

Wang, H., Luo, X., Ye, M., Hou, J., Robinson, H., Ke, H.

(2010) J Med Chem 53: 1726-1731

Released	2010-02-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (protein)
Unique Ligands	BYE, MG, ZN

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3K3S \| pdb_00003k3s	Download File View File

Crystal structure of altronate hydrolase (fragment 1-84) from Shigella Flexneri.

Hou, J., Chruszcz, M., Xu, X., Le, B., Zimmerman, M.D., Savchenko, A., Edwards, A.M., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)

To be published

Released	2009-10-27
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Shigella flexneri 2a str. 2457T
Macromolecule	Altronate hydrolase (protein)
Unique Ligands	ACT, CL, MLA

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3N3Z \| pdb_00003n3z	Download File View File

Crystal structure of PDE9A (E406A) mutant in complex with IBMX

Hou, J., Luo, H.-B., Chen, Y., Xu, J., Zhao, R., Zou, L.

To be published

Released	2011-04-13
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Homo sapiens
Macromolecule	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (protein)
Unique Ligands	CL, IBM, MG, ZN

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3NDQ \| pdb_00003ndq	Download File View File

Structure of Human TFIIS Domain II

Hu, X.P., Averell, G., Ye, X.Y., Hou, J., Luo, H.

To be published

Released	2011-05-18
Method	X-RAY DIFFRACTION 1.933 Å
Organisms	Homo sapiens
Macromolecule	Transcription elongation factor A protein 1 (protein)
Unique Ligands	NA

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3OP4 \| pdb_00003op4	Download File View File

Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with NADP+

Hou, J., Chruszcz, M., Onopriyenko, O., Grimshaw, S., Porebski, P., Zheng, H., Savchenko, A., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2010-09-22
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Vibrio cholerae O1 biovar El Tor str. N16961
Macromolecule	3-oxoacyl-[acyl-carrier protein] reductase (protein)
Unique Ligands	ACT, NAP

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3QI3 \| pdb_00003qi3	Download File View File

Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691

Hou, J., Xu, J., Liu, M., Zhao, R., Lou, H., Ke, H.

(2011) PLoS One 6: e18092-e18092

Released	2011-04-27
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (protein)
Unique Ligands	MG, PDB, ZN

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3QI4 \| pdb_00003qi4	Download File View File

Crystal structure of PDE9A(Q453E) in complex with IBMX

Hou, J., Xu, J., Liu, M., Zhao, R., Lou, H., Ke, H.

(2011) PLoS One 6: e18092-e18092

Released	2011-04-27
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (protein)
Unique Ligands	IBM, MG, ZN

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3RRO \| pdb_00003rro	Download File View File

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Vibrio cholerae

Hou, J., Chruszcz, M., Cooper, D.R., Grabowski, M., Zheng, H., Osinski, T., Shumilin, I., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2011-05-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Vibrio cholerae O1 biovar El Tor str. N16961
Macromolecule	3-ketoacyl-(acyl-carrier-protein) reductase (protein)
Unique Ligands	CL, EDO, GOL, PGE, SO4

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3RSH \| pdb_00003rsh	Download File View File

Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)

Hou, J., Chruszcz, M., Cooper, D.R., Grabowski, M., Zheng, H., Osinski, T., Shumilin, I., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2011-05-11
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Vibrio cholerae O1 biovar El Tor str. N16961
Macromolecule	3-oxoacyl-[acyl-carrier protein] reductase (protein)
Unique Ligands	EDO, NAP, SO4, UNX

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3T5P \| pdb_00003t5p	Download File View File

Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne

Hou, J., Zheng, H., Chruszcz, M., Cooper, D.R., Onopriyenko, O., Grimshaw, S., Savchenko, A., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2011-09-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bacillus anthracis str. Sterne
Macromolecule	BmrU protein (protein)
Unique Ligands	MG

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3TZC \| pdb_00003tzc	Download File View File

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(Y155F) from Vibrio cholerae

Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Domagalski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2011-10-19
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Vibrio cholerae MJ-1236
Macromolecule	3-oxoacyl-[acyl-carrier protein] reductase (protein)
Unique Ligands	NAP, SO4

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3TZH \| pdb_00003tzh	Download File View File

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(F187A) from Vibrio cholerae

Hou, J., Chruszcz, M., Zheng, H., Cooper, D.R., Osinski, T., Shumilin, I., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

Released	2011-10-19
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Vibrio cholerae MJ-1236
Macromolecule	3-oxoacyl-[acyl-carrier protein] reductase (protein)
Unique Ligands	GOL, SO4, UNX

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3TZK \| pdb_00003tzk	Download File View File

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92A) from Vibrio cholerae

Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Domagalski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2011-10-19
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Vibrio cholerae MJ-1236
Macromolecule	3-oxoacyl-[acyl-carrier protein] reductase (protein)
Unique Ligands	SO4, UNX

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3U09 \| pdb_00003u09	Download File View File

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae

Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Fratczak, Z., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Bacteriol 198: 463-476

Released	2011-10-19
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Vibrio cholerae O1 biovar El Tor str. N16961
Macromolecule	3-oxoacyl-[acyl-carrier-protein] reductase FabG (protein)
Unique Ligands	SO4, UNX

1 to 25 of 52 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1YP1 | pdb_00001yp1

2OUN | pdb_00002oun

2OUP | pdb_00002oup

2OUQ | pdb_00002ouq

2OUR | pdb_00002our

2OUS | pdb_00002ous

2OUU | pdb_00002ouu

2OUV | pdb_00002ouv

2OUY | pdb_00002ouy

3ICC | pdb_00003icc

3K3E | pdb_00003k3e

3K3H | pdb_00003k3h

3K3S | pdb_00003k3s

3N3Z | pdb_00003n3z

3NDQ | pdb_00003ndq

3OP4 | pdb_00003op4

3QI3 | pdb_00003qi3

3QI4 | pdb_00003qi4

3RRO | pdb_00003rro

3RSH | pdb_00003rsh

3T5P | pdb_00003t5p

3TZC | pdb_00003tzc

3TZH | pdb_00003tzh

3TZK | pdb_00003tzk

3U09 | pdb_00003u09