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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Xiao, T.S."

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Search Summary

This query matches 55 Structures.

Refinements

Structure Determination Methodology

experimental (55)

Scientific Name of Source Organism

	Severe acute respiratory syndrome coronavirus 2 (31)
	Homo sapiens (20)
	Mus musculus (8)
	Brucella melitensis (1)
	Drosophila melanogaster (1)
	Escherichia coli O157:H7 (1)
	Gallus gallus (1)
	Saccharomyces cerevisiae S288C (1)
	Vaccinia virus (1)

Taxonomy

	Riboviria (31)
	Eukaryota (28)
	Bacteria (2)
	Varidnaviria (1)

Experimental Method

	ELECTRON MICROSCOPY (29)
	X-RAY DIFFRACTION (26)

Polymer Entity Type

	Protein (55)
	DNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (8)
	2.0 - 2.5 (8)
	2.5 - 3.0 (6)
	3.0 - 3.5 (17)
	3.5 - 4.0 (8)
	4.0 - 4.5 (5)
	> 4.5 (1)

Release Date

	2010 - 2014 (5)
	2015 - 2019 (12)
	2020 - 2024 (38)

Enzyme Classification Name

	Hydrolases (14)
	Transferases (2)

Symmetry Type

	Asymmetric (42)
	Cyclic (13)

SCOP Classification

	All alpha proteins (1)
	Alpha and beta proteins (a/b) (1)
	Artifacts (1)

AllSelected

1 to 25 of 55 Structures

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3VD8 \| pdb_00003vd8	Download File View File

Crystal structure of human AIM2 PYD domain with MBP fusion

Jin, T.C., Perry, A., Smith, P., Xiao, T.S.

(2013) J Biological Chem 288: 13225-13235

Released	2013-01-16
Method	X-RAY DIFFRACTION 2.0685 Å
Organisms	Escherichia coli O157:H7 Homo sapiens
Macromolecule	Maltose-binding periplasmic protein, Interferon-inducible protein AIM2 (protein)
Unique Ligands	EDO, K
Unique branched monosaccharides	GLC

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4EO7 \| pdb_00004eo7	Download File View File

Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.

Snyder, G.A., Cirl, C., Jiang, J.S., Chen, P., Smith, T., Xiao, T.S.

(2013) Proc Natl Acad Sci U S A 110: 6985-6990

Released	2013-04-10
Method	X-RAY DIFFRACTION 1.449 Å
Organisms	Homo sapiens
Macromolecule	Myeloid differentiation primary response protein MyD88 (protein)
Unique Ligands	MG

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4LQC \| pdb_00004lqc	Download File View File

The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry.

Snyder, G.A., Smith, P., Fresquez, T., Cirl, C., Jiang, J., Snyder, N., Luchetti, T., Miethke, T., Xiao, T.S.

(2014) J Biological Chem 289: 669-679

Released	2013-12-04
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Brucella melitensis
Macromolecule	TcpB (protein)

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4LQD \| pdb_00004lqd	Download File View File

The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry

Snyder, G.A., Smith, P., Jiang, J., Xiao, T.S.

(2014) J Biological Chem 289: 669-679

Released	2013-12-04
Method	X-RAY DIFFRACTION 2.451 Å
Organisms	Homo sapiens
Macromolecule	Toll/interleukin-1 receptor domain-containing adapter protein (protein)
Unique Ligands	GOL

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4M6B \| pdb_00004m6b	Download File View File

Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer

Hong, J.J., Feng, H.Q., Wang, F., Ranjan, A., Chen, J.H., Jiang, J.S., Girlando, R., Xiao, T.S., Wu, C., Bai, Y.W.

(2014) Mol Cell 53: 498-505

Released	2014-02-19
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Chimera protein of Histone H2B.1 and Histone H2A.Z (protein) Helicase SWR1 (protein)

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4QLC \| pdb_00004qlc	Download File View File

Crystal structure of chromatosome at 3.5 angstrom resolution

Jiang, J.S., Zhou, B.R., Xiao, T.S., Bai, Y.W.

(2015) Mol Cell 33 Suppl 1: 2-3

Released	2015-07-22
Method	X-RAY DIFFRACTION 3.503 Å
Organisms	Drosophila melanogaster Gallus gallus Homo sapiens
Macromolecule	Unique protein chains: 5 Unique nucleic acid chains: 2
Unique Ligands	CIT

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5H7N \| pdb_00005h7n	Download File View File

Crystal structure of human NLRP12-PYD with a MBP tag

Jin, T.C., Xiao, T.S.

(2017) Sci Rep 7: 40991-40991

Released	2017-02-15
Method	X-RAY DIFFRACTION 1.849 Å
Organisms	Homo sapiens
Macromolecule	NLRP12-PYD with MBP tag (protein)
Unique Ligands	EDO, PEG, SO4
Unique branched monosaccharides	GLC

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5H7Q \| pdb_00005h7q	Download File View File

Crystal structure of human MNDA PYD domain with MBP tag

Jin, T.C., Xiao, T.S.

(2017) Sci Rep 7: 40991-40991

Released	2017-02-15
Method	X-RAY DIFFRACTION 1.451 Å
Organisms	Homo sapiens
Macromolecule	MNDA PYD domain with MBP tag (protein)
Unique Ligands	ACT
Unique branched monosaccharides	GLC

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5WPZ \| pdb_00005wpz	Download File View File

Crystal structure of MNDA PYD with MBP tag

Jin, T.C., Xiao, T.S.

(2017) Sci Rep 7: 40991-40991

Released	2017-02-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	MBP-hMNDA-PYD (protein)
Unique branched monosaccharides	GLC

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5WQ6 \| pdb_00005wq6	Download File View File

Crystal Structure of hMNDA-PYD with MBP tag

Jin, T.C., Xiao, T.S.

(2017) Sci Rep 7: 40991-40991

Released	2017-02-15
Method	X-RAY DIFFRACTION 1.648 Å
Organisms	Homo sapiens
Macromolecule	MBP tagged hMNDA-PYD (protein)
Unique Ligands	ACT, EDO
Unique branched monosaccharides	GLC

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5Y3S \| pdb_00005y3s	Download File View File

Crystal structure of human NLRP1 leucine rich repeat domain

Jin, T., Xiao, T.S.

To be published

Released	2018-08-01
Method	X-RAY DIFFRACTION 2.451 Å
Organisms	Homo sapiens
Macromolecule	NACHT, LRR and PYD domains-containing protein 1 (protein)
Unique Ligands	NA, PO4

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5Z7D \| pdb_00005z7d	Download File View File

p204HINab-dsDNA complex structure

Jin, T., Jiang, J., Xiao, T.S.

(2021) Nucleic Acids Res

Released	2019-01-30
Method	X-RAY DIFFRACTION 4.5 Å
Organisms	Mus musculus Vaccinia virus
Macromolecule	Interferon-activable protein 204 (protein) DNA (5'-D(PCPCPAPTPCPAPGPAPAPAPGPAPGPAPGPC)-3') (nucleic acid)

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6AO3 \| pdb_00006ao3	Download File View File

Crystal structure of the murine gasdermin D C-terminal domain

Liu, Z., Wang, C., Yang, J., Xiao, T.S.

(2018) Structure 26: 778-784.e3

Released	2018-04-11
Method	X-RAY DIFFRACTION 1.76 Å
Organisms	Mus musculus
Macromolecule	Gasdermin-D (protein)

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6AO4 \| pdb_00006ao4	Download File View File

Crystal structure of the human gasdermin D C-terminal domain

Liu, Z., Wang, C., Yang, J., Xiao, T.S.

(2018) Structure 26: 778-784.e3

Released	2018-04-11
Method	X-RAY DIFFRACTION 2.901 Å
Organisms	Homo sapiens
Macromolecule	Gasdermin-D (protein)

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6BZ9 \| pdb_00006bz9	Download File View File

Crystal structure of human caspase-1 in complex with Ac-FLTD-CMK

Xiao, T.S., Yang, J., Liu, Z., Wang, C., Yang, R.

(2018) Proc Natl Acad Sci U S A 115: 6792-6797

Released	2018-06-13
Method	X-RAY DIFFRACTION 1.796 Å
Organisms	Homo sapiens
Macromolecule	Ac-FLTD-CMK (protein) Caspase-1 (protein)
Unique Ligands	PEG

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6N9N \| pdb_00006n9n	Download File View File

Crystal structure of murine GSDMD

Liu, Z., Wang, C., Yang, J., Xiao, T.S.

(2019) Immunity 51: 43

Released	2019-06-05
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Mus musculus
Macromolecule	Gasdermin-D (protein)

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6N9O \| pdb_00006n9o	Download File View File

Crystal structure of human GSDMD

Liu, Z., Wang, C., Yang, J., Xiao, T.S.

(2019) Immunity 51: 43

Released	2019-06-05
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens
Macromolecule	Gasdermin-D (protein)

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6NRY \| pdb_00006nry	Download File View File

Crystal structure of human caspase-4

Yang, J., Liu, Z., Shi, W., Xiao, T.S.

To be published

Released	2020-07-29
Method	X-RAY DIFFRACTION 2.184 Å
Organisms	Homo sapiens
Macromolecule	Caspase-4 (protein)
Unique Ligands	GOL

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6NS7 \| pdb_00006ns7	Download File View File

Crystal structure of murine caspase-11

Yang, J., Liu, Z., Xiao, T.S.

To be published

Released	2020-07-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	Caspase-11 (protein)
Unique Ligands	SO4

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6PZP \| pdb_00006pzp	Download File View File

Crystal structure of caspase-1 in complex with VX-765

Yang, J., Liu, Z., Xiao, T.S.

To be published

Released	2020-08-05
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Homo sapiens
Macromolecule	Caspase-1 (protein)
Unique Ligands	P7S

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6UP2 \| pdb_00006up2	Download File View File

Crystal structure of the murine DHX36 helicase

Chuenchor, W., Jiang, J., Xiao, T.S.

To be published

Released	2020-10-28
Method	X-RAY DIFFRACTION 1.97 Å
Organisms	Mus musculus
Macromolecule	Dhx36 protein (protein)
Unique Ligands	CL, GOL

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6UP3 \| pdb_00006up3	Download File View File

Crystal structure of the murine DHX36 helicase in complex with ANP

Chuenchor, W., Jiang, J., Xiao, T.S.

To be published

Released	2020-10-28
Method	X-RAY DIFFRACTION 2.691 Å
Organisms	Mus musculus
Macromolecule	Dhx36 protein (protein)
Unique Ligands	ANP

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6UP4 \| pdb_00006up4	Download File View File

Crystal structure of the murine DHX36 helicase in complex with ADP

Liu, Z., Xiao, T.S.

(2020) J Mol Biology 432: 2217-2231

Released	2020-04-15
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	Dhx36 protein (protein)
Unique Ligands	ADP, MG

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6VIE \| pdb_00006vie	Download File View File

Structure of caspase-1 in complex with gasdermin D

Liu, Z., Xiao, T.S.

(2020) Immunity 53: 106

Released	2020-07-01
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Caspase-1 subunit p10 (protein) Caspase-1 subunit p20 (protein) Gasdermin-D (protein)

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6XR8 \| pdb_00006xr8	Download File View File

Distinct conformational states of SARS-CoV-2 spike protein

Zhang, J., Cai, Y.F., Xiao, T.S., Peng, H.Q., Sterling, S.M., Walsh Jr, R.M., Rawson, S., Volloch, S.R., Chen, B.

(2020) Science 369: 1586-1592

Released	2020-07-22
Method	ELECTRON MICROSCOPY 2.9 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	Spike glycoprotein (protein)
Unique Ligands	NAG
Unique branched monosaccharides	FUC, MAN, NAG

1 to 25 of 55 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

3VD8 | pdb_00003vd8

4EO7 | pdb_00004eo7

4LQC | pdb_00004lqc

4LQD | pdb_00004lqd

4M6B | pdb_00004m6b

4QLC | pdb_00004qlc

5H7N | pdb_00005h7n

5H7Q | pdb_00005h7q

5WPZ | pdb_00005wpz

5WQ6 | pdb_00005wq6

5Y3S | pdb_00005y3s

5Z7D | pdb_00005z7d

6AO3 | pdb_00006ao3

6AO4 | pdb_00006ao4

6BZ9 | pdb_00006bz9

6N9N | pdb_00006n9n

6N9O | pdb_00006n9o

6NRY | pdb_00006nry

6NS7 | pdb_00006ns7

6PZP | pdb_00006pzp

6UP2 | pdb_00006up2

6UP3 | pdb_00006up3

6UP4 | pdb_00006up4

6VIE | pdb_00006vie

6XR8 | pdb_00006xr8