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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Chen, Z."

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Search Summary

This query matches 1,178 Structures.

Refinements

Structure Determination Methodology

experimental (1,178)

Scientific Name of Source Organism

	Homo sapiens (633)
	Severe acute respiratory syndrome coronavirus 2 (83)
	Mus musculus (78)
	synthetic construct (54)
	Saccharomyces cerevisiae S288C (41)
	Arabidopsis thaliana (40)
	Coxsackievirus B1 (26)
	Xenopus laevis (21)
	Coxsackievirus A16 (16)
	Rattus norvegicus (15)

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Taxonomy

	Eukaryota (892)
	Riboviria (246)
	Bacteria (145)
	other sequences (56)
	Duplodnaviria (54)
	Eukaryota (eukaryotes) (11)
	Varidnaviria (6)
	Archaea (4)
	Riboviria (RNA viruses and viroids) (3)
	unclassified sequences (3)

Experimental Method

	X-RAY DIFFRACTION (828)
	ELECTRON MICROSCOPY (327)
	SOLUTION NMR (23)

Polymer Entity Type

	Protein (1,178)
	DNA (76)
	RNA (15)

Refinement Resolution (Å)

	0.5 - 1.0 (1)
	1.0 - 1.5 (45)
	1.5 - 2.0 (216)
	2.0 - 2.5 (261)
	2.5 - 3.0 (252)
	3.0 - 3.5 (207)
	3.5 - 4.0 (94)
	4.0 - 4.5 (35)
	> 4.5 (44)

Release Date

	1980 - 1984 (2)
	1990 - 1994 (3)
	1995 - 1999 (22)
	2000 - 2004 (23)
	2005 - 2009 (85)
	2010 - 2014 (223)
	2015 - 2019 (275)
	2020 - 2024 (533)
	2025 - 2029 (12)

Enzyme Classification Name

	Hydrolases (319)
	Transferases (200)
	Oxidoreductases (102)
	Isomerases (17)
	Lyases (14)
	Translocases (8)
	Ligases (4)

Membrane Protein Annotation

	PDBTM (88)
	mpstruc (73)
	OPM (50)
	MemProtMD (44)

Symmetry Type

	Asymmetric (844)
	Cyclic (244)
	Icosahedral (73)
	Dihedral (42)
	Helical (2)
	Octahedral (1)

SCOP Classification

	All beta proteins (171)
	Alpha and beta proteins (a/b) (109)
	Alpha and beta proteins (a+b) (132)
	Artifacts (92)
	All alpha proteins (69)
	Small proteins (25)
	Membrane and cell surface proteins and peptides (4)
	Coiled coil proteins (7)
	Multi-domain proteins (alpha and beta) (1)
	Peptides (1)

AllSelected

1 to 25 of 1,178 Structures

Page 1 of 48

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1A1W \| pdb_00001a1w	Download File View File

FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE

Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.

(1998) Nature 392: 941-945

Released	1998-12-30
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	FADD PROTEIN (protein)

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1A1Z \| pdb_00001a1z	Download File View File

FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE

Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.

(1998) Nature 392: 941-945

Released	1998-12-30
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	FADD PROTEIN (protein)

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1AAR \| pdb_00001aar	Download File View File

STRUCTURE OF A DIUBIQUITIN CONJUGATE AND A MODEL FOR INTERACTION WITH UBIQUITIN CONJUGATING ENZYME (E2)

Cook, W.J., Jeffrey, L.C., Carson, M., Chen, Z., Pickart, C.M.

(1992) J Biological Chem 267: 16467-16471

Released	1993-10-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bos taurus
Macromolecule	DI-UBIQUITIN (protein)

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1AHT \| pdb_00001aht	Download File View File

CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND P-AMIDINOPHENYLPYRUVATE AT 1.6 ANGSTROMS RESOLUTION

Chen, Z.

(1995) Arch Biochem Biophys 322: 198-203

Released	1996-03-17
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) HIRUGEN (protein)
Unique Ligands	APA

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1BFZ \| pdb_00001bfz	Download File View File

BOUND CONFORMATION OF N-TERMINAL CLEAVAGE PRODUCT PEPTIDE MIMIC (P1-P9 OF RELEASE SITE) WHILE BOUND TO HCMV PROTEASE AS DETERMINED BY TRANSFERRED NOESY EXPERIMENTS (P1-P5 SHOWN ONLY), NMR, 32 STRUCTURES

Laplante, S.R., Aubry, N., Bonneau, P.R., Cameron, D.R., Lagace, L., Massariol, M.-J., Montpetit, H., Ploufe, C., Kawai, S.H., Fulton, B.D., Chen, Z., Ni, F.

(1998) Biochemistry 37: 9793-9801

Released	1999-05-25
Method	SOLUTION NMR
Macromolecule	HCMV PROTEASE R-SITE N-TERMINAL CLEAVAGE PRODUCT (protein)

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1BG0 \| pdb_00001bg0	Download File View File

TRANSITION STATE STRUCTURE OF ARGININE KINASE

Zhou, G., Somasundaram, T., Blanc, E., Parthasarathy, G., Ellington, W.R., Chapman, M.S.

(1998) Proc Natl Acad Sci U S A 95: 8449-8454

Released	1998-10-14
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Limulus polyphemus
Macromolecule	ARGININE KINASE (protein)
Unique Ligands	ADP, DAR, MG, NO3

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1BHG \| pdb_00001bhg	Download File View File

HUMAN BETA-GLUCURONIDASE AT 2.6 A RESOLUTION

Jain, S., Drendel, W.B.

(1996) Nat Struct Biol 3: 375-381

Released	1997-09-17
Method	X-RAY DIFFRACTION 2.53 Å
Organisms	Homo sapiens
Macromolecule	BETA-GLUCURONIDASE (protein)
Unique branched monosaccharides	BMA, MAN, NAG

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1BT7 \| pdb_00001bt7	Download File View File

THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES

Barbato, G., Cicero, D.O., Nardi, M.C., Steinkuhler, C., Cortese, R., De Francesco, R., Bazzo, R.

(1999) J Mol Biology 289: 371-384

Released	1999-06-22
Method	SOLUTION NMR
Organisms	Hepacivirus hominis
Macromolecule	NS3 SERINE PROTEASE (protein)
Unique Ligands	ZN

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1BXA \| pdb_00001bxa	Download File View File

AMICYANIN REDUCED, PH 4.4, 1.3 ANGSTROMS

Cunane, L.M., Chen, Z.W., Durley, R.C.E., Mathews, F.S.

(1998) Biochemistry 37: 17128-17136

Released	1998-10-07
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Paracoccus denitrificans
Macromolecule	PROTEIN (AMICYANIN) (protein)
Unique Ligands	CU1

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1C6V \| pdb_00001c6v	Download File View File

SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)

Chen, Z., Yan, Y., Munshi, S., Li, Y., Zruygay-Murphy, J., Xu, B., Witmer, M., Felock, P., Wolfe, A., Sardana, V., Emini, E.A., Hazuda, D., Kuo, L.C.

(2000) J Mol Biology 296: 521-533

Released	2000-12-27
Method	X-RAY DIFFRACTION 3 Å
Organisms	Simian immunodeficiency virus
Macromolecule	PROTEIN (SIU89134) (protein) PROTEIN (SIV INTEGRASE) (protein)

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1C6X \| pdb_00001c6x	Download File View File

ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.

Munshi, S.

(2000) Acta Crystallogr D Biol Crystallogr 56: 381-388

Released	2000-12-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	PROTEIN (PROTEASE) (protein)
Unique Ligands	3IN

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1C6Y \| pdb_00001c6y	Download File View File

ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.

Munshi, S.

(2000) Acta Crystallogr D Biol Crystallogr 56: 381-388

Released	2000-12-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	PROTEIN (PROTEASE) (protein)
Unique Ligands	MK1

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1C6Z \| pdb_00001c6z	Download File View File

ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.

Munshi, S.

(2000) Acta Crystallogr D Biol Crystallogr 56: 381-388

Released	2000-12-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	PROTEIN (PROTEASE) (protein)
Unique Ligands	ROC

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1C70 \| pdb_00001c70	Download File View File

ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.

Munshi, S.

(2000) Acta Crystallogr D Biol Crystallogr 56: 381-388

Released	2000-12-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	PROTEIN (PROTEASE) (protein)
Unique Ligands	L75

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1DJN \| pdb_00001djn	Download File View File

STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT WILD TYPE TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1)

Trickey, P., Basran, J., Lian, L.-Y., Chen, Z.-W., Barton, J.D., Sutcliffe, M.J., Scrutton, N.S., Mathews, F.S.

(2000) Biochemistry 39: 7678-7688

Released	1999-12-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methylophilus methylotrophus W3A1
Macromolecule	TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, FMN, SF4

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1DJQ \| pdb_00001djq	Download File View File

STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT C30A MUTANT OF TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1)

Trickey, P., Basran, J., Lian, L.-Y., Chen, Z.-W., Barton, J.D., Sutcliffe, M.J., Scrutton, N.S., Mathews, F.S.

(2000) Biochemistry 39: 7678-7688

Released	1999-12-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methylophilus methylotrophus W3A1
Macromolecule	TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, FMN, SF4

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1EKM \| pdb_00001ekm	Download File View File

CRYSTAL STRUCTURE AT 2.5 A RESOLUTION OF ZINC-SUBSTITUTED COPPER AMINE OXIDASE OF HANSENULA POLYMORPHA EXPRESSED IN ESCHERICHIA COLI

Chen, Z., Schwartz, B., Williams, N.K., Li, R., Klinman, J.P., Mathews, F.S.

(2000) Biochemistry 39: 9709-9717

Released	2000-08-23
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Ogataea angusta
Macromolecule	COPPER AMINE OXIDASE (protein)
Unique Ligands	ZN

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1FVY \| pdb_00001fvy	Download File View File

SOLUTION STRUCTURE OF THE OSTEOGENIC 1-31 FRAGMENT OF THE HUMAN PARATHYROID HORMONE

Chen, Z.

(2000) Biochemistry 39: 12766-12777

Released	2000-11-22
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PARATHYROID HORMONE (protein)

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1GG4 \| pdb_00001gg4	Download File View File

CRYSTAL STRUCTURE OF ESCHERICHIA COLI UDPMURNAC-TRIPEPTIDE D-ALANYL-D-ALANINE-ADDING ENZYME (MURF) AT 2.3 ANGSTROM RESOLUTION

Yan, Y., Munshi, S., Chen, Z.

(2000) J Mol Biology 304: 435-445

Released	2000-12-20
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2,6-DIAMINOPIMELATE-D-ALANYL-D-ALANYL LIGASE (protein)

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1HSG \| pdb_00001hsg	Download File View File

CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES

Chen, Z.

(1994) J Biological Chem 269: 26344-26348

Released	1996-04-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	HIV-1 PROTEASE (protein)
Unique Ligands	MK1

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1HSH \| pdb_00001hsh	Download File View File

CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES

Chen, Z.

(1994) J Biological Chem 269: 26344-26348

Released	1996-04-03
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Human immunodeficiency virus type 2 (ISOLATE ROD)
Macromolecule	HIV-II PROTEASE (protein)
Unique Ligands	MK1