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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Forssmann, W.G."

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Search Summary

This query matches 281 Structures.

Refinements

Structure Determination Methodology

experimental (281)

Scientific Name of Source Organism

	Saccharomyces cerevisiae S288C (122)
	Homo sapiens (82)
	synthetic construct (36)
	Drosophila melanogaster (12)
	Cellvibrio japonicus Ueda107 (10)
	Acidobacterium capsulatum (9)
	Meripilus giganteus (8)
	Mus musculus (8)
	Saccharomyces cerevisiae (7)
	Cellvibrio japonicus (6)

More...

Taxonomy

	Eukaryota (198)
	Bacteria (83)
	other sequences (36)

Experimental Method

X-RAY DIFFRACTION (281)

Polymer Entity Type

Protein (281)

Refinement Resolution (Å)

	0.5 - 1.0 (2)
	1.0 - 1.5 (31)
	1.5 - 2.0 (77)
	2.0 - 2.5 (37)
	2.5 - 3.0 (120)
	3.0 - 3.5 (14)

Release Date

	2000 - 2004 (4)
	2010 - 2014 (10)
	2015 - 2019 (155)
	2020 - 2024 (110)
	2025 - 2029 (2)

Enzyme Classification Name

	Hydrolases (243)
	Transferases (20)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Cyclic (161)
	Asymmetric (114)
	Dihedral (7)

SCOP Classification

	Alpha and beta proteins (a+b) (92)
	Artifacts (90)
	Alpha and beta proteins (a/b) (18)
	All beta proteins (12)

AllSelected

1 to 25 of 281 Structures

Page 1 of 12

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1KYI \| pdb_00001kyi	Download File View File

HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex

Sousa, M.C., Kessler, B.M., Overkleeft, H.S., McKay, D.B.

(2002) J Mol Biology 318: 779-785

Released	2002-05-15
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Haemophilus influenzae Rd KW20
Macromolecule	ATP-dependent hsl protease ATP-binding subunit hslU (protein) ATP-dependent protease hslV (protein)
Unique Ligands	ATP, LVS

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1OFH \| pdb_00001ofh	Download File View File

Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae)

Kwon, A.R., Kessler, B.M., Overkleeft, H.S., McKay, D.B.

(2003) J Mol Biology 330: 185

Released	2003-07-03
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Haemophilus influenzae Rd KW20
Macromolecule	ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU (protein) ATP-DEPENDENT PROTEASE HSLV (protein)
Unique Ligands	ADP, MG, PO4

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1OFI \| pdb_00001ofi	Download File View File

Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae)

Kwon, A.R., Kessler, B.M., Overkleeft, H.S., McKay, D.B.

(2003) J Mol Biology 330: 185

Released	2003-07-03
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Haemophilus influenzae Rd KW20
Macromolecule	ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU (protein) ATP-DEPENDENT PROTEASE HSLV (protein)
Unique Ligands	ADP, LVS, MG, PO4

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1XD3 \| pdb_00001xd3	Download File View File

Crystal structure of UCHL3-UbVME complex

Misaghi, S., Galardy, P.J., Meester, W.J.N., Ovaa, H., Ploegh, H.L., Gaudet, R.

(2005) J Biological Chem 280: 1512-1520

Released	2004-11-23
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Homo sapiens
Macromolecule	UBC protein (protein) Ubiquitin Carboxyl-terminal esterase L3 (protein)
Unique Ligands	GVE, MG

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4INR \| pdb_00004inr	Download File View File

Yeast 20S proteasome in complex with the vinyl sulfone LU102

Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E.M., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F.

(2013) J Med Chem 56: 1262-1275

Released	2013-01-30
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Unique protein chains: 14
Unique Ligands	1G1

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4INT \| pdb_00004int	Download File View File

Yeast 20S proteasome in complex with the vinyl sulfone LU122

(2013) J Med Chem 56: 1262-1275

Released	2013-01-30
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Unique protein chains: 14
Unique Ligands	1G5

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4INU \| pdb_00004inu	Download File View File

Yeast 20S proteasome in complex with the vinyl sulfone LU112

(2013) J Med Chem 56: 1262-1275

Released	2013-01-30
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Unique protein chains: 14
Unique Ligands	1G6

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4QLQ \| pdb_00004qlq	Download File View File

yCP in complex with tripeptidic epoxyketone inhibitor 8

De Bruin, G., Huber, E., Xin, B., Van Rooden, E., Al-Ayed, K., Kim, K., Kisselev, A., Driessen, C., Van der Marel, G., Groll, M., Overkleeft, H.

(2014) J Med Chem 57: 6197-6209

Released	2014-07-23
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Unique protein chains: 14
Unique Ligands	38N, MES, MG

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4QLS \| pdb_00004qls	Download File View File

yCP in complex with tripeptidic epoxyketone inhibitor 11

De Bruin, G., Huber, E., Xin, B., Van Rooden, E., Al-Ayed, K., Kim, K., Kisselev, A., Driessen, C., Van der Marel, G., Groll, M., Overkleeft, H.

(2014) J Med Chem 57: 6197-6209

Released	2014-07-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Unique protein chains: 14
Unique Ligands	37Y, MES, MG

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4QLT \| pdb_00004qlt	Download File View File

yCP in complex with tripeptidic epoxyketone inhibitor 2 (PR924)

de Bruin, G., Huber, E., Xin, B., van Rooden, E., Al-Ayed, K., Kim, K., Kisselev, A., Driessen, C., van der Marel, G., Groll, M., Overkleeft, H.

(2014) J Med Chem 57: 6197-6209

Released	2014-07-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Unique protein chains: 14
Unique Ligands	39V, MES, MG

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4QLU \| pdb_00004qlu	Download File View File

yCP in complex with tripeptidic epoxyketone inhibitor 9

de Bruin, G., Huber, E., Xin, B., van Rooden, E., Al-Ayed, K., Kim, K., Kisselev, A., Driessen, C., van der Marel, G., Groll, M., Overkleeft, H.

(2014) J Med Chem 57: 6197-6209

Released	2014-07-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Unique protein chains: 14
Unique Ligands	38X, MES, MG

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4QLV \| pdb_00004qlv	Download File View File

yCP in complex with tripeptidic epoxyketone inhibitor 17

de Bruin, G., Huber, E., Xin, B., van Rooden, E., Al-Ayed, K., Kim, K., Kisselev, A., Driessen, C., van der Marel, G., Groll, M., Overkleeft, H.

(2014) J Med Chem 57: 6197-6209

Released	2014-07-23
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Unique protein chains: 14
Unique Ligands	39Q, MES, MG

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4WSJ \| pdb_00004wsj	Download File View File

Crystal structure of a bacterial fucodiase in complex with 1-((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)ethan-1-one

Davies, G.J., Wright, D.W.

(2015) Chem Sci 6: 2782-false

Released	2014-11-05
Method	X-RAY DIFFRACTION 1.64 Å
Organisms	Bacteroides thetaiotaomicron VPI-5482
Macromolecule	Alpha-L-fucosidase (protein)
Unique Ligands	3U3, SO4

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4WSK \| pdb_00004wsk	Download File View File

Crystal structure of a bacterial fucosidase with phenyl((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)methanone

Davies, G.J.

(2015) Chem Sci 6: 2782-false

Released	2014-11-12
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Bacteroides thetaiotaomicron VPI-5482
Macromolecule	Alpha-L-fucosidase (protein)
Unique Ligands	3U2, IMD, SO4

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4Y69 \| pdb_00004y69	Download File View File

Yeast 20S proteasome in complex with Ac-PAD-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MG

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4Y6A \| pdb_00004y6a	Download File View File

Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAD-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MG

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4Y6V \| pdb_00004y6v	Download File View File

Yeast 20S proteasome in complex with Ac-PAE-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	MG

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4Y6Z \| pdb_00004y6z	Download File View File

Yeast 20S proteasome in complex with Ac-PAL-ep

Groll, M., Huber, E.M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

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4Y70 \| pdb_00004y70	Download File View File

Yeast 20S proteasome in complex with Ac-LAV-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

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4Y74 \| pdb_00004y74	Download File View File

Yeast 20S proteasome in complex with Ac-LAL-ep

Groll, M., Huber, E.M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

Explore in 3D

4Y75 \| pdb_00004y75	Download File View File

Yeast 20S proteasome in complex with Ac-PAF-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

Explore in 3D

4Y77 \| pdb_00004y77	Download File View File

Yeast 20S proteasome in complex with Ac-LAF-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

Explore in 3D

4Y78 \| pdb_00004y78	Download File View File

Yeast 20S proteasome in complex with Ac-LAD-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

Explore in 3D

4Y7W \| pdb_00004y7w	Download File View File

Yeast 20S proteasome in complex with Ac-LAE-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

Explore in 3D

4Y7X \| pdb_00004y7x	Download File View File

Yeast 20S proteasome in complex with Ac-PAA-ep

Huber, E.M., Groll, M.

(2015) J Am Chem Soc 137: 7835-7842

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Saccharomyces cerevisiae S288C synthetic construct
Macromolecule	Unique protein chains: 15
Unique Ligands	CL, MES, MG

1 to 25 of 281 Structures

Page 1 of 12

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1KYI | pdb_00001kyi

1OFH | pdb_00001ofh

1OFI | pdb_00001ofi

1XD3 | pdb_00001xd3

4INR | pdb_00004inr

4INT | pdb_00004int

4INU | pdb_00004inu

4QLQ | pdb_00004qlq

4QLS | pdb_00004qls

4QLT | pdb_00004qlt

4QLU | pdb_00004qlu

4QLV | pdb_00004qlv

4WSJ | pdb_00004wsj

4WSK | pdb_00004wsk

4Y69 | pdb_00004y69

4Y6A | pdb_00004y6a

4Y6V | pdb_00004y6v

4Y6Z | pdb_00004y6z

4Y70 | pdb_00004y70

4Y74 | pdb_00004y74

4Y75 | pdb_00004y75

4Y77 | pdb_00004y77

4Y78 | pdb_00004y78

4Y7W | pdb_00004y7w

4Y7X | pdb_00004y7x