RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "Hirth, B."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 11 Structures.

Refinements

Structure Determination Methodology

experimental (11)

Scientific Name of Source Organism

Homo sapiens (11)

Taxonomy

Eukaryota (11)

Experimental Method

X-RAY DIFFRACTION (11)

Polymer Entity Type

Protein (11)

Refinement Resolution (Å)

	1.5 - 2.0 (3)
	2.0 - 2.5 (7)
	2.5 - 3.0 (1)

Release Date

2010 - 2014 (11)

Enzyme Classification Name

Transferases (11)

Symmetry Type

Asymmetric (11)

SCOP Classification

Alpha and beta proteins (a+b) (11)

AllSelected

1 to 11 of 11 Structures

Page 1 of 1

Sort by

Explore in 3D

3R00 \| pdb_00003r00	Download File View File

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Liu, J.

(2011) Bioorg Med Chem Lett 21: 3050-3056

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	IMD, UNJ

Explore in 3D

3R01 \| pdb_00003r01	Download File View File

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Liu, J.

(2011) Bioorg Med Chem Lett 21: 3050-3056

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	IMD, UNE

Explore in 3D

3R02 \| pdb_00003r02	Download File View File

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Xiang, Y., Hirth, B., Asmussen, G., Biemann, H.-P., Good, A., Fitzgerald, M., Gladysheva, T., Jancsics, K., Liu, J., Metz, M., Papoulis, A., Skerlj, R., Stepp, D.J., Wei, R.R.

(2011) Bioorg Med Chem Lett 21: 3050-3056

Released	2011-05-11
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	IMD, UNM

Explore in 3D

3R04 \| pdb_00003r04	Download File View File

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Xiang, Y., Hirth, B., Asmussen, G., Biemann, H.-P., Good, A., Fitzgerald, M., Gladysheva, T., Jancsics, K., Liu, J., Metz, M., Papoulis, A., Skerlj, R., Stepp, D.J., Wei, R.R.

(2011) Bioorg Med Chem Lett 21: 3050-3056

Released	2011-05-11
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	IMD, UNQ

Explore in 3D

3VBQ \| pdb_00003vbq	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0F5

Explore in 3D

3VBT \| pdb_00003vbt	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.23 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0F9

Explore in 3D

3VBV \| pdb_00003vbv	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0FK

Explore in 3D

3VBW \| pdb_00003vbw	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.48 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0FN

Explore in 3D

3VBX \| pdb_00003vbx	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0FO

Explore in 3D

3VBY \| pdb_00003vby	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0FR, IMD

Explore in 3D

3VC4 \| pdb_00003vc4	Download File View File

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Liu, J.

(2012) J Med Chem 55: 2641-2648

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.23 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase pim-1 (protein)
Unique Ligands	0FS, IMD

1 to 11 of 11 Structures

Page 1 of 1

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

3R00 | pdb_00003r00

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

3R01 | pdb_00003r01

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

3R02 | pdb_00003r02

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

3R04 | pdb_00003r04

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

3VBQ | pdb_00003vbq

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VBT | pdb_00003vbt

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VBV | pdb_00003vbv

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VBW | pdb_00003vbw

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VBX | pdb_00003vbx

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VBY | pdb_00003vby

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

3VC4 | pdb_00003vc4

Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

3R00 | pdb_00003r00

3R01 | pdb_00003r01

3R02 | pdb_00003r02

3R04 | pdb_00003r04

3VBQ | pdb_00003vbq

3VBT | pdb_00003vbt

3VBV | pdb_00003vbv

3VBW | pdb_00003vbw

3VBX | pdb_00003vbx

3VBY | pdb_00003vby

3VC4 | pdb_00003vc4