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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Knapp, S."

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Search Summary

This query matches 1,043 Structures.

Refinements

Structure Determination Methodology

experimental (1,043)

Scientific Name of Source Organism

	Homo sapiens (883)
	Mus musculus (131)
	synthetic construct (23)
	Lama glama (7)
	Severe acute respiratory syndrome coronavirus 2 (7)
	Plasmodium falciparum 3D7 (4)
	Serratia marcescens (4)
	Streptomyces plicatus (3)
	Thermotoga maritima (3)
	Bos taurus (2)

More...

Taxonomy

	Eukaryota (1,021)
	other sequences (23)
	Bacteria (12)
	Riboviria (7)
	Archaea (3)
	Eukaryota (eukaryotes) (2)
	unclassified sequences (1)

Experimental Method

	X-RAY DIFFRACTION (1,023)
	ELECTRON MICROSCOPY (16)
	SOLUTION NMR (4)

Polymer Entity Type

	Protein (1,043)
	DNA (3)

Refinement Resolution (Å)

	1.0 - 1.5 (197)
	1.5 - 2.0 (413)
	2.0 - 2.5 (299)
	2.5 - 3.0 (103)
	3.0 - 3.5 (19)
	3.5 - 4.0 (6)
	4.0 - 4.5 (1)
	> 4.5 (1)

Release Date

	1995 - 1999 (6)
	2000 - 2004 (15)
	2005 - 2009 (165)
	2010 - 2014 (193)
	2015 - 2019 (214)
	2020 - 2024 (438)
	2025 - 2029 (12)

Enzyme Classification Name

	Transferases (648)
	Hydrolases (107)
	Oxidoreductases (12)
	Ligases (3)
	Isomerases (2)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (927)
	Cyclic (131)
	Dihedral (18)

SCOP Classification

	Alpha and beta proteins (a+b) (272)
	All alpha proteins (229)
	Artifacts (219)
	Alpha and beta proteins (a/b) (52)
	All beta proteins (16)
	Small proteins (5)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 1,043 Structures

Page 1 of 42

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1B06 \| pdb_00001b06	Download File View File

SUPEROXIDE DISMUTASE FROM SULFOLOBUS ACIDOCALDARIUS

Knapp, S., Kardinahl, S., Niklas, H., Tibbelin, G., Schafer, G., Ladenstein, R.

(1999) J Mol Biology 285: 689-702

Released	1999-11-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Sulfolobus acidocaldarius DSM 639
Macromolecule	PROTEIN (SUPEROXIDE DISMUTASE) (protein)
Unique Ligands	FE

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1B26 \| pdb_00001b26	Download File View File

GLUTAMATE DEHYDROGENASE

Knapp, S., Devos, W.M., Rice, D., Ladenstein, R.

(1997) J Mol Biology 267: 916-932

Released	1999-12-03
Method	X-RAY DIFFRACTION 3 Å
Organisms	Thermotoga maritima
Macromolecule	GLUTAMATE DEHYDROGENASE (protein)

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1B3B \| pdb_00001b3b	Download File View File

THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K

Knapp, S., Lebbink, J.H.G., Van Der Oost, J., Devos, W.M., Rice, D., Ladenstein, R.

(1998) J Mol Biology 280: 287-296

Released	1999-12-08
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Thermotoga maritima
Macromolecule	PROTEIN (GLUTAMATE DEHYDROGENASE) (protein)

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1BBX \| pdb_00001bbx	Download File View File

NON-SPECIFIC PROTEIN-DNA INTERACTIONS IN THE SSO7D-DNA COMPLEX, NMR, 1 STRUCTURE

Agback, P., Baumann, H., Knapp, S., Ladenstein, R., Hard, T.

(1998) Nat Struct Biol 5: 579-584

Released	1998-10-14
Method	SOLUTION NMR
Organisms	Saccharolobus solfataricus
Macromolecule	DNA-BINDING PROTEIN 7D (protein) DNA (5'-D(CPTPAPGPCPGPCPGPCPTPAPG)-3') (nucleic acid)

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1GO4 \| pdb_00001go4	Download File View File

Crystal structure of Mad1-Mad2 reveals a conserved Mad2 binding motif in Mad1 and Cdc20.

Sironi, L., Mapelli, M., Jeang, K.T., Musacchio, A.

(2002) EMBO J 21: 2496-2506

Released	2002-05-16
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Mitotic spindle assembly checkpoint protein MAD1 (protein) Mitotic spindle assembly checkpoint protein MAD2A (protein)

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1HP4 \| pdb_00001hp4	Download File View File

CRYSTAL STRUCTURE OF STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE

Mark, B.L.

(2001) J Biological Chem 276: 10330-10337

Released	2001-04-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Streptomyces plicatus
Macromolecule	BETA-N-ACETYLHEXOSAMINIDASE (protein)
Unique Ligands	CL, GOL, SO4

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1HP5 \| pdb_00001hp5	Download File View File

STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE COMPLEXED WITH INTERMEDIATE ANALOUGE NAG-THIAZOLINE

Mark, B.L.

(2001) J Biological Chem 276: 10330-10337

Released	2001-04-04
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Streptomyces plicatus
Macromolecule	BETA-N-ACETYLHEXOSAMINIDASE (protein)
Unique Ligands	CL, GOL, NGT, SO4

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1JAK \| pdb_00001jak	Download File View File

Streptomyces plicatus beta-N-acetylhexosaminidase in Complex with (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidinium chloride (IFG)

Mark, B.L., Vocadlo, D.J., Zhao, D., Knapp, S., Withers, S.G., James, M.N.

(2001) J Biological Chem 276: 42131-42137

Released	2001-11-21
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Streptomyces plicatus
Macromolecule	Beta-N-acetylhexosaminidase (protein)
Unique Ligands	CL, GOL, IFG, SO4

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1NOU \| pdb_00001nou	Download File View File

Native human lysosomal beta-hexosaminidase isoform B

Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.

(2003) J Mol Biology 327: 1093-1109

Released	2003-04-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	beta-hexosaminidase beta chain (protein)
Unique Ligands	GOL, SO4
Unique branched monosaccharides	NAG

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1NOW \| pdb_00001now	Download File View File

Human lysosomal beta-hexosaminidase isoform B in complex with (2R,3R,4S,5R)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium Chloride (GalNAc-isofagomine)

Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.

(2003) J Mol Biology 327: 1093-1109

Released	2003-04-29
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	beta-hexosaminidase beta chain (protein)
Unique Ligands	GOL, IFG, SO4
Unique branched monosaccharides	NAG

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1NP0 \| pdb_00001np0	Download File View File

Human lysosomal beta-hexosaminidase isoform B in complex with intermediate analogue NAG-thiazoline

Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.

(2003) J Mol Biology 327: 1093-1109

Released	2003-04-29
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Beta-hexosaminidase subunit beta (protein) Beta-hexosaminidase subunit beta chain A (protein) Beta-hexosaminidase subunit beta chain B (protein)
Unique Ligands	GOL, NGT, SO4
Unique branched monosaccharides	NAG

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1PYX \| pdb_00001pyx	Download File View File

GSK-3 Beta complexed with AMP-PNP

Bertrand, J.A., Thieffine, S., Vulpetti, A., Cristiani, C., Valsasina, B., Knapp, S., Kalisz, H.M., Flocco, M.

(2003) J Mol Biology 333: 393-407

Released	2003-10-21
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Glycogen synthase kinase-3 beta (protein)
Unique Ligands	ANP, MG

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1Q3D \| pdb_00001q3d	Download File View File

GSK-3 Beta complexed with Staurosporine

Bertrand, J.A., Thieffine, S., Vulpetti, A., Cristiani, C., Valsasina, B., Knapp, S., Kalisz, H.M., Flocco, M.

(2003) J Mol Biology 333: 393-407

Released	2003-10-21
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	GLYCOGEN SYNTHASE KINASE-3 BETA (protein)
Unique Ligands	STU

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1Q3W \| pdb_00001q3w	Download File View File

GSK-3 Beta complexed with Alsterpaullone

Bertrand, J.A., Thieffine, S., Vulpetti, A., Cristiani, C., Valsasina, B., Knapp, S., Kalisz, H.M., Flocco, M.

(2003) J Mol Biology 333: 393-407

Released	2003-10-21
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	GLYCOGEN SYNTHASE KINASE-3 BETA (protein)
Unique Ligands	ATU

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1Q41 \| pdb_00001q41	Download File View File

GSK-3 Beta complexed with Indirubin-3'-monoxime

Bertrand, J.A., Thieffine, S., Vulpetti, A., Cristiani, C., Valsasina, B., Knapp, S., Kalisz, H.M., Flocco, M.

(2003) J Mol Biology 333: 393-407

Released	2003-10-21
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	GLYCOGEN SYNTHASE KINASE-3 BETA (protein)
Unique Ligands	IXM

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1Q4L \| pdb_00001q4l	Download File View File

GSK-3 Beta complexed with Inhibitor I-5

Bertrand, J.A., Thieffine, S., Vulpetti, A., Cristiani, C., Valsasina, B., Knapp, S., Kalisz, H.M., Flocco, M.

(2003) J Mol Biology 333: 393-407

Released	2003-10-14
Method	X-RAY DIFFRACTION 2.77 Å
Organisms	Homo sapiens
Macromolecule	GLYCOGEN SYNTHASE KINASE-3 BETA (protein)
Unique Ligands	679

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1R0P \| pdb_00001r0p	Download File View File

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a

Schiering, N., Knapp, S., Marconi, M., Flocco, M.M., Cui, J., Perego, R., Rusconi, L., Cristiani, C.

(2003) Proc Natl Acad Sci U S A 100: 12654-12659

Released	2003-10-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hepatocyte growth factor receptor (protein)
Unique Ligands	KSA

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1R1W \| pdb_00001r1w	Download File View File

CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET

Schiering, N., Knapp, S., Marconi, M., Flocco, M.M., Cui, J., Perego, R., Rusconi, L., Cristiani, C.

(2003) Proc Natl Acad Sci U S A 100: 12654-12659

Released	2003-10-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	HEPATOCYTE GROWTH FACTOR RECEPTOR (protein)

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1SSO \| pdb_00001sso	Download File View File

SOLUTION STRUCTURE AND DNA-BINDING PROPERTIES OF A THERMOSTABLE PROTEIN FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS

Baumann, H., Knapp, S., Lundback, T., Ladenstein, R., Hard, T.

(1994) Nat Struct Biol 1: 808-819

Released	1995-05-08
Method	SOLUTION NMR
Organisms	Saccharolobus solfataricus
Macromolecule	SSO7D (protein)

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1VYH \| pdb_00001vyh	Download File View File

PAF-AH Holoenzyme: Lis1/Alfa2

Tarricone, C., Perrina, F., Monzani, S., Massimiliano, L., Knapp, S., Tsai, L.-H., Derewenda, Z.S., Musacchio, A.

(2004) Neuron 44: 809

Released	2005-05-26
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT (protein) PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT (protein)

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1XWS \| pdb_00001xws	Download File View File

Crystal Structure of the human PIM1 kinase domain

Knapp, S., Debreczeni, J., Bullock, A., von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Guo, K.

To be published

Released	2004-11-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene serine/threonine-protein kinase Pim-1 (protein)
Unique Ligands	BI1, SO4