RCSB PDB: Search

1K4R \| pdb_00001k4r	Download File View File

Structure of Dengue Virus

Kuhn, R.J., Zhang, W., Rossmann, M.G., Pletnev, S.V., Corver, J., Lenches, E., Jones, C.T., Mukhopadhyay, S., Chipman, P.R., Strauss, E.G., Baker, T.S., Strauss, J.H.

(2002) Cell 108: 717-725

Released	2002-03-13
Method	ELECTRON MICROSCOPY 24 Å
Organisms	Chimeric Tick-borne encephalitis virus/Dengue virus 4
Macromolecule	MAJOR ENVELOPE PROTEIN E (protein)

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1LD4 \| pdb_00001ld4	Download File View File

Placement of the Structural Proteins in Sindbis Virus

Zhang, W., Mukhopadhyay, S., Pletnev, S.V., Baker, T.S., Kuhn, R.J., Rossmann, M.G.

(2002) J Virol 76: 11645-11658

Released	2002-11-04
Method	ELECTRON MICROSCOPY 11.4 Å
Organisms	Saccharomyces cerevisiae Sindbis virus
Macromolecule	Coat protein C (protein) GENERAL CONTROL PROTEIN GCN4 (protein) Spike glycoprotein E1 (protein)
Unique Ligands	UNX

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1NN8 \| pdb_00001nn8	Download File View File

CryoEM structure of poliovirus receptor bound to poliovirus

He, Y., Mueller, S., Chipman, P.R., Bator, C.M., Peng, X., Bowman, V.D., Mukhopadhyay, S., Wimmer, E., Kuhn, R.J., Rossmann, M.G.

(2003) J Virol 77: 4827-4835

Released	2004-01-27
Method	ELECTRON MICROSCOPY 15 Å
Organisms	Homo sapiens Human poliovirus 1 Mahoney
Macromolecule	coat protein VP1 (protein) coat protein VP2 (protein) coat protein VP3 (protein) coat protein VP4 (protein) poliovirus receptor (protein)
Unique Ligands	MYR

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1P58 \| pdb_00001p58	Download File View File

Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction

Zhang, W., Chipman, P.R., Corver, J., Johnson, P.R., Zhang, Y., Mukhopadhyay, S., Baker, T.S., Strauss, J.H., Rossmann, M.G., Kuhn, R.J.

(2003) Nat Struct Biol 10: 907-912

Released	2003-11-04
Method	ELECTRON MICROSCOPY 9.5 Å
Organisms	Dengue virus 2 Puerto Rico/PR159-S1/1969
Macromolecule	Envelope protein M (protein) Major envelope protein E (protein)

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1THD \| pdb_00001thd	Download File View File

COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION

Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G.

(2004) Structure 12: 1607-1618

Released	2004-09-28
Method	ELECTRON MICROSCOPY 9.5 Å
Organisms	Dengue virus 2 Puerto Rico/PR159-S1/1969
Macromolecule	Major envelope protein E (protein)

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1Z8Y \| pdb_00001z8y	Download File View File

Mapping the E2 Glycoprotein of Alphaviruses

Mukhopadhyay, S., Zhang, W., Gabler, S., Chipman, P.R., Strauss, E.G., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G.

(2006) Structure 14: 63-73

Released	2006-02-07
Method	ELECTRON MICROSCOPY 9 Å
Organisms	Sindbis virus
Macromolecule	Capsid protein C (protein) Spike glycoprotein E1 (protein) Spike glycoprotein E2 (protein)

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2IIR \| pdb_00002iir	Download File View File

Acetate kinase from a hypothermophile Thermotoga maritima

Mukhopadhyay, S., Hasson, M.S., Sanders, D.A.

To be published

Released	2007-09-11
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Thermotoga maritima
Macromolecule	Acetate kinase (protein)

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2XFB \| pdb_00002xfb	Download File View File

CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEINS FITTED IN SINDBIS VIRUS cryo- EM MAP

Voss, J.E., Vaney, M.C., Duquerroy, S., Rey, F.A.

(2010) Nature 468: 709

Released	2010-11-24
Method	ELECTRON MICROSCOPY 9 Å
Organisms	Chikungunya virus
Macromolecule	E1 ENVELOPE GLYCOPROTEIN (protein) E2 ENVELOPE GLYCOPROTEIN (protein)

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3SZA \| pdb_00003sza	Download File View File

Crystal structure of human ALDH3A1 - apo form

Khanna, M., Hurley, T.D.

(2011) J Biological Chem 286: 43486-43494

Released	2011-11-02
Method	X-RAY DIFFRACTION 1.48 Å
Organisms	Homo sapiens
Macromolecule	Aldehyde dehydrogenase, dimeric NADP-preferring (protein)
Unique Ligands	ACT, K

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3SZB \| pdb_00003szb	Download File View File

Crystal structure of human ALDH3A1 modified with the beta-elimination product of Aldi-1; 1-phenyl- 2-propen-1-one

Khanna, M., Hurley, T.D.

(2011) J Biological Chem 286: 43486-43494

Released	2011-11-02
Method	X-RAY DIFFRACTION 1.51 Å
Organisms	Homo sapiens
Macromolecule	Aldehyde dehydrogenase (protein)
Unique Ligands	ACT, I1E, K

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4BW5 \| pdb_00004bw5	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1)

Pike, A.C.W., Dong, Y.Y., Dong, L., Quigley, A., Shrestha, L., Mukhopadhyay, S., Strain-Damerell, C., Goubin, S., Grieben, M., Shintre, C.A., Mackenzie, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N., Carpenter, E.P.

(2015) Science 347: 1256

Released	2013-07-31
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 (protein)
Unique Ligands	CD, K, PC1

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4FRR \| pdb_00004frr	Download File View File

X-ray structure of Acetylcholine binding protein from Aplysia californica in presence of 3-((S)-azetidin-2-ylmethoxy)-5-((1S,2R)-2-(2-methoxyethyl)cyclopropyl)pyridine

Mukhopadhyay, S., Mesecar, A.D.

To be published

Released	2013-10-16
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Aplysia californica
Macromolecule	Soluble acetylcholine receptor (protein)
Unique Ligands	0VC, GOL

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4TWK \| pdb_00004twk	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1)

Pike, A.C.W., Dong, Y.Y., Tessitore, A., Goubin, S., Strain-Damerell, C., Mukhopadhyay, S., Kupinska, K., Wang, D., Chalk, R., Berridge, G., Grieben, M., Shrestha, L., Ang, J.H., Mackenzie, A., Quigley, A., Bushell, S.R., Shintre, C.A., Faust, B., Chu, A., Dong, L., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P.

To be published

Released	2014-08-06
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Potassium channel subfamily K member 2 (protein)
Unique Ligands	37X, K, MG, NAG

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4XDJ \| pdb_00004xdj	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)

Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Homo sapiens
Macromolecule	POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 (protein)
Unique Ligands	K, PC1, TRD

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4XDK \| pdb_00004xdk	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine

Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.6 Å
Organisms	Homo sapiens
Macromolecule	Potassium channel subfamily K member 10 (protein)
Unique Ligands	405, 408, K, PC1

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4XDL \| pdb_00004xdl	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with a brominated fluoxetine derivative.

Mackenzie, A., Pike, A.C.W., Dong, Y.Y., Mukhopadhyay, S., Ruda, G.F., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens
Macromolecule	Potassium channel subfamily K member 10 (protein)
Unique Ligands	40D, CD, K, PC1

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5C65 \| pdb_00005c65	Download File View File

Structure of the human glucose transporter GLUT3 / SLC2A3

Pike, A.C.W., Quigley, A., Chu, A., Tessitore, A., Xia, X., Mukhopadhyay, S., Wang, D., Kupinska, K., Strain-Damerell, C., Chalk, R., Burgess-Brown, N.A., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

To be published

Released	2015-07-08
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Solute carrier family 2, facilitated glucose transporter member 3 (protein)
Unique Ligands	37X, Y01

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5K47 \| pdb_00005k47	Download File View File

CryoEM structure of the human Polycystin-2/PKD2 TRP channel

Pike, A.C.W., Grieben, M., Shintre, C.A., Tessitore, A., Shrestha, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2017) Nat Struct Mol Biol 24: 114-122

Released	2016-08-24
Method	ELECTRON MICROSCOPY 4.22 Å
Organisms	Homo sapiens
Macromolecule	Polycystin-2 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

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5OCH \| pdb_00005och	Download File View File

The crystal structure of human ABCB8 in an outward-facing state

Faust, B., Pike, A.C.W., Shintre, C.A., Quiqley, A.M., Chu, A., Barr, A., Shrestha, L., Mukhopadhyay, S., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

To be published

Released	2018-07-25
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Homo sapiens
Macromolecule	ATP-binding cassette sub-family B member 8, mitochondrial (protein)
Unique Ligands	ADP, MG, Y01

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6GYN \| pdb_00006gyn	Download File View File

Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel

Shintre, C.A., Pike, A.C.W., Tessitore, A., Young, M., Bushell, S.R., Strain-Damerell, C., Mukhopadhyay, S., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

To be published

Released	2019-05-08
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (protein)
Unique Ligands	3PE, PC1

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6GYO \| pdb_00006gyo	Download File View File

Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Shintre, C.A., Pike, A.C.W., Tessitore, A., Young, M., Bushell, S.R., Strain-Damerell, C., Mukhopadhyay, S., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

To be published

Released	2019-05-01
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (protein)
Unique Ligands	3PE, CMP, PC1, PIE, UNX

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6JTZ \| pdb_00006jtz	Download File View File

Crystal Structure of hRecQ1_D2-Zn-WH containing mutation on beta-hairpin

Das, T., Mukhopadhyay, S., Bose, M., Das, A.K., Ganguly, A.

(2021) Nucleic Acids Res

Released	2020-04-15
Method	X-RAY DIFFRACTION 2.797 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent DNA helicase Q1 (protein)
Unique Ligands	ZN

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6Y6C \| pdb_00006y6c	Download File View File

TREM2 extracellular domain (19-174) in complex with single-chain variable fragment (scFv-4)

Szykowska, A., Preger, C., Williams, E., Mukhopadhyay, S.M.M., McKinley, G., Gruslund, S., Wigren, E., Persson, H., Arrowsmith, C.H., Edwards, A., von Delft, F., Bountra, C., Davis, J.B., Di Daniel, E., Burgess-Brown, N., Bullock, A.

(2021) Structure 29: 1241-1252.e5

Released	2021-02-17
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Homo sapiens
Macromolecule	Single chain variable (protein) Triggering receptor expressed on myeloid cells 2 (protein)
Unique Ligands	NAG

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6YMQ \| pdb_00006ymq	Download File View File

TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4)

Szykowska, A., Preger, C., Scacioc, A., Mukhopadhyay, S.M.M., McKinley, G., Graslund, S., Wigren, E., Persson, H., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Di Daniel, E., Davis, J.B., Burgess-Brown, N., Bullock, A.

(2021) Structure 29: 1241-1252.e5

Released	2021-02-17
Method	X-RAY DIFFRACTION 3.07 Å
Organisms	Homo sapiens
Macromolecule	Single-chain variable 4 (protein) Triggering receptor expressed on myeloid cells 2 (protein)
Unique Ligands	MPD, NAG

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6YYE \| pdb_00006yye	Download File View File

TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2)

Szykowska, A., Preger, C., Krojer, T., Mukhopadhyay, S.M.M., McKinley, G., Graslund, S., Wigren, E., Persson, H., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Di Daniel, E., Burgess-Brown, N., Bullock, A.

(2021) Structure 29: 1241-1252.e5

Released	2021-02-17
Method	X-RAY DIFFRACTION 3.36 Å
Organisms	Homo sapiens
Macromolecule	TREM2 Single chain variable 2 (protein) Triggering receptor expressed on myeloid cells 2 (protein)
Unique Ligands	NAG

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1K4R | pdb_00001k4r

1LD4 | pdb_00001ld4

1NN8 | pdb_00001nn8

1P58 | pdb_00001p58

1THD | pdb_00001thd

1Z8Y | pdb_00001z8y

2IIR | pdb_00002iir

2XFB | pdb_00002xfb

3SZA | pdb_00003sza

3SZB | pdb_00003szb

4BW5 | pdb_00004bw5

4FRR | pdb_00004frr

4TWK | pdb_00004twk

4XDJ | pdb_00004xdj

4XDK | pdb_00004xdk

4XDL | pdb_00004xdl

5C65 | pdb_00005c65

5K47 | pdb_00005k47

5OCH | pdb_00005och

6GYN | pdb_00006gyn

6GYO | pdb_00006gyo

6JTZ | pdb_00006jtz

6Y6C | pdb_00006y6c

6YMQ | pdb_00006ymq

6YYE | pdb_00006yye