RCSB PDB: Search

3E25 \| pdb_00003e25	Download File View File

Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase

Pereira, P.J.B., Empadinhas, N., Costa, M.S., Macedo-Ribeiro, S.

(2008) PLoS One 3: e3748-e3748

Released	2008-12-02
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	Putative uncharacterized protein (protein)
Unique Ligands	3PG, MG, UDP

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3E26 \| pdb_00003e26	Download File View File

Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase

Pereira, P.J.B., Empadinhas, N., Costa, M.S., Macedo-Ribeiro, S.

(2008) PLoS One 3: e3748-e3748

Released	2008-12-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	Putative uncharacterized protein (protein)

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4U94 \| pdb_00004u94	Download File View File

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

Fraga, J., Empadinhas, N., Pereira, P.J.B., Macedo-Ribeiro, S.

(2015) Sci Rep 5: 8026-8026

Released	2015-02-11
Method	X-RAY DIFFRACTION 1.473 Å
Organisms	Mycolicibacterium vanbaalenii PYR-1
Macromolecule	Maltokinase (protein)
Unique Ligands	MG

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4U98 \| pdb_00004u98	Download File View File

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (AppCp complex)

Fraga, J., Empadinhas, N., Pereira, P.J.B., Macedo-Ribeiro, S.

(2015) Sci Rep 5: 8026-8026

Released	2015-02-11
Method	X-RAY DIFFRACTION 1.15 Å
Organisms	Mycolicibacterium vanbaalenii PYR-1
Macromolecule	Maltokinase (protein)
Unique Ligands	ACP, MG

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4WZY \| pdb_00004wzy	Download File View File

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (ATP complex)

Fraga, J., Empadinhas, N., Pereira, P.J.B., Macedo-Ribeiro, S.

(2015) Sci Rep 5: 8026-8026

Released	2015-02-11
Method	X-RAY DIFFRACTION 1.71 Å
Organisms	Mycolicibacterium vanbaalenii PYR-1
Macromolecule	Maltokinase (protein)
Unique Ligands	ATP, MG

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5CGM \| pdb_00005cgm	Download File View File

Structure of Mycobacterium thermoresistibile GlgE in complex with maltose at 1.95A resolution

Mendes, V., Blaszczyk, M., Maranha, A., Empadinhas, N., Blundell, T.L.

(2015) Sci Rep 5: 17144-17144

Released	2015-12-09
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Mycolicibacterium thermoresistibile ATCC 19527
Macromolecule	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase (protein)
Unique Ligands	1PE, CL, EDO, NA, PEG, PG4, PGE, PO4
Unique branched monosaccharides	GLC

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5CIM \| pdb_00005cim	Download File View File

Structure of Mycobacterium thermoresistibile GlgE in complex with maltose (cocrystallisation with maltose-1-phosphate) at 3.32A resolution

Mendes, V., Blaszczyk, M., Maranha, A., Empadinhas, N., Blundell, T.L.

(2015) Sci Rep 5: 17144-17144

Released	2015-12-09
Method	X-RAY DIFFRACTION 3.32 Å
Organisms	Mycolicibacterium thermoresistibile ATCC 19527
Macromolecule	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase (protein)
Unique branched monosaccharides	GLC

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5CJ5 \| pdb_00005cj5	Download File View File

Structure of Mycobacterium thermoresistibile GlgE APO form at 3.13A resolution

Mendes, V., Blaszczyk, M., Maranha, A., Empadinhas, N., Blundell, T.L.

(2015) Sci Rep 5: 17144-17144

Released	2015-12-09
Method	X-RAY DIFFRACTION 3.13 Å
Organisms	Mycolicibacterium thermoresistibile ATCC 19527
Macromolecule	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase (protein)

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5JIJ \| pdb_00005jij	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase (APO form).

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-05-10
Method	X-RAY DIFFRACTION 1.82 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	EDO, NHE

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5JIO \| pdb_00005jio	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase ternary complex with ADP and Glucose-6-phosphate.

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-05-10
Method	X-RAY DIFFRACTION 1.711 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	ADP, EDO, G6P

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5K41 \| pdb_00005k41	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex with ADP-glucose.

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-06-21
Method	X-RAY DIFFRACTION 1.971 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	ADQ, EDO, NHE

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5K42 \| pdb_00005k42	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex with GDP-glucose.

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-06-21
Method	X-RAY DIFFRACTION 1.921 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	EDO, GDG, NHE

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5K44 \| pdb_00005k44	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex with Trehalose-6-phosphate.

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-06-21
Method	X-RAY DIFFRACTION 1.925 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	EDO, NHE
Unique branched monosaccharides	G6P, GLC

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5K5C \| pdb_00005k5c	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a complex with Trehalose.

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-06-07
Method	X-RAY DIFFRACTION 1.848 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	EDO, NHE
Unique branched monosaccharides	GLC

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5L3K \| pdb_00005l3k	Download File View File

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a ternary complex with ADP and fructose-6-phosphate

Mendes, V., Verma, N., Blaszczyk, M., Blundell, T.L.

(2019) mBio 10:

Released	2017-06-07
Method	X-RAY DIFFRACTION 2.305 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	Alpha,alpha-trehalose-phosphate synthase (protein)
Unique Ligands	ADP, EDO, F6P, PO4

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5MWO \| pdb_00005mwo	Download File View File

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.

Mendes, V., Chan, D.S.-H., Thomas, S.E., McConnell, B., Matak-Vinkovic, D., Coyne, A.G., Abell, C., Blundell, T.L.

(2017) Angew Chem Int Ed Engl 56: 7488-7491

Released	2017-05-31
Method	X-RAY DIFFRACTION 1.962 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	EDO, J6W

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5MXK \| pdb_00005mxk	Download File View File

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9.

Mendes, V., Chan, D.S.-H., Thomas, S.E., McConnell, B., Matak-Vinkovic, D., Coyne, A.G., Abell, C., Blundell, T.L.

(2017) Angew Chem Int Ed Engl 56: 7488-7491

Released	2017-05-31
Method	X-RAY DIFFRACTION 1.932 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	EDO, ZHA

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5MXV \| pdb_00005mxv	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK1107112A at 1.63A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.626 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	K3T

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5MYL \| pdb_00005myl	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK1570606A at 1.72A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.724 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	Q2N

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5MYM \| pdb_00005mym	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK2032710A at 2.28A resolution

Mendes, V., Blaszczyk, M., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 2.28 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	EDO, HYV

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5MYN \| pdb_00005myn	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK445886A at 1.56A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.564 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	ZUF

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5MYR \| pdb_00005myr	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK735816A at 1.83A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.828 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	UDY

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5MYS \| pdb_00005mys	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK920684A at 1.59A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.587 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	YP6

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5MYT \| pdb_00005myt	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound GSK921295A at 1.61A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	ZQC

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5MYW \| pdb_00005myw	Download File View File

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound SB-435634 at 1.77A resolution

Blaszczyk, M., Mendes, V., Mugumbate, G., Blundell, T.L.

(2017) Front Pharmacol 8: 681-681

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	HTH-type transcriptional regulator EthR (protein)
Unique Ligands	WCU

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

3E25 | pdb_00003e25

3E26 | pdb_00003e26

4U94 | pdb_00004u94

4U98 | pdb_00004u98

4WZY | pdb_00004wzy

5CGM | pdb_00005cgm

5CIM | pdb_00005cim

5CJ5 | pdb_00005cj5

5JIJ | pdb_00005jij

5JIO | pdb_00005jio

5K41 | pdb_00005k41

5K42 | pdb_00005k42

5K44 | pdb_00005k44

5K5C | pdb_00005k5c

5L3K | pdb_00005l3k

5MWO | pdb_00005mwo

5MXK | pdb_00005mxk

5MXV | pdb_00005mxv

5MYL | pdb_00005myl

5MYM | pdb_00005mym

5MYN | pdb_00005myn

5MYR | pdb_00005myr

5MYS | pdb_00005mys

5MYT | pdb_00005myt

5MYW | pdb_00005myw