RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "Thamm, S."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 9 Structures.

Refinements

Structure Determination Methodology

experimental (9)

Scientific Name of Source Organism

	Homo sapiens (8)
	Vicugna pacos (3)
	Mus musculus (1)

Taxonomy

Eukaryota (9)

Experimental Method

	X-RAY DIFFRACTION (4)
	ELECTRON MICROSCOPY (3)
	SOLUTION NMR (2)

Polymer Entity Type

Protein (9)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (3)
	3.0 - 3.5 (3)

Release Date

	2015 - 2019 (2)
	2020 - 2024 (7)

Enzyme Classification Name

	Transferases (3)
	Hydrolases (2)

Membrane Protein Annotation

	PDBTM (3)
	MemProtMD (2)

Symmetry Type

	Asymmetric (6)
	Cyclic (3)

SCOP Classification

	Alpha and beta proteins (a/b) (2)
	Artifacts (1)

AllSelected

1 to 9 of 9 Structures

Page 1 of 1

Sort by

Explore in 3D

6H8R \| pdb_00006h8r	Download File View File

CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND 2

Hoerer, S., Fiegen, D., Schnapp, G.

(2019) J Med Chem 62: 306-316

Released	2018-09-26
Method	X-RAY DIFFRACTION 1.66 Å
Organisms	Homo sapiens
Macromolecule	Tyrosine-protein phosphatase non-receptor type 5 (protein)
Unique Ligands	FWB, SO4

Explore in 3D

6H8S \| pdb_00006h8s	Download File View File

CRYSTAL STRUCTURE OF THE MOUSE PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND BI-0314

Fiegen, D., Schnapp, G.

(2019) J Med Chem 62: 306-316

Released	2018-09-26
Method	X-RAY DIFFRACTION 1.771 Å
Organisms	Mus musculus
Macromolecule	Tyrosine-protein phosphatase non-receptor type 5 (protein)
Unique Ligands	FSZ

Explore in 3D

6ZLE \| pdb_00006zle	Download File View File

Solution structure of unliganded MLKL executioner domain

Ruebbelke, M., Bauer, M., Nar, H., Zeeb, M.

(2020) Proc Natl Acad Sci U S A 117: 33272-33281

Released	2020-12-16
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Mixed lineage kinase domain-like protein (protein)

Explore in 3D

6ZPR \| pdb_00006zpr	Download File View File

Solution structure of MLKL executioner domain in complex with a covalent inhibitor

Ruebbelke, M., Bauer, M., Hamilton, J., Binder, F., Nar, H., Zeeb, M.

(2020) Proc Natl Acad Sci U S A 117: 33272-33281

Released	2020-12-16
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Mixed lineage kinase domain-like protein,Mixed lineage kinase domain-like protein (protein)
Unique Ligands	QOK

Explore in 3D

6ZVO \| pdb_00006zvo	Download File View File

Crystal structure of unliganded MLKL executioner domain

Fiegen, D., Bauer, M., Nar, H.

(2020) Proc Natl Acad Sci U S A 117: 33272-33281

Released	2020-12-23
Method	X-RAY DIFFRACTION 1.371 Å
Organisms	Homo sapiens
Macromolecule	Mixed lineage kinase domain-like protein (protein)
Unique Ligands	BR, CL

Explore in 3D

6ZZ1 \| pdb_00006zz1	Download File View File

Crystal structure of MLKL executioner domain in complex with a covalent inhibitor

Fiegen, D., Bauer, M., Nar, H.

(2020) Proc Natl Acad Sci U S A 117: 33272-33281

Released	2020-12-23
Method	X-RAY DIFFRACTION 1.64 Å
Organisms	Homo sapiens
Macromolecule	Mixed lineage kinase domain-like protein (protein)
Unique Ligands	QOK

Explore in 3D

8QZ6 \| pdb_00008qz6	Download File View File

Structure of human ceramide synthase 6 (CerS6) bound to C16:0

Pascoa, T.C., Pike, A.C.W., Chi, G., Stefanic, S., Quigley, A., Chalk, R., Mukhopadhyay, S.M.M., Venkaya, S., Dix, C., Moreira, T., Tessitore, A., Cole, V., Chu, A., Elkins, J.M., Pautsch, A., Schnapp, G., Carpenter, E.P., Sauer, D.B.

(2025) Nat Struct Mol Biol 32: 431-440

Released	2024-11-13
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens Vicugna pacos
Macromolecule	Isoform 2 of Ceramide synthase 6 (protein) Nanobody-22 (protein)
Unique Ligands	NAG, PC1, PLM

Explore in 3D

8QZ7 \| pdb_00008qz7	Download File View File

Structure of human ceramide synthase 6 (CerS6) in complex with N-palmitoyl fumonisin B1

(2025) Nat Struct Mol Biol 32: 431-440

Released	2024-11-13
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Homo sapiens Vicugna pacos
Macromolecule	Isoform 2 of Ceramide synthase 6 (protein) Nanobody-22 (protein)
Unique Ligands	NAG, PC1, XBX

Explore in 3D

9EOT \| pdb_00009eot	Download File View File

Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)

(2025) Nat Struct Mol Biol 32: 431-440

Released	2024-11-13
Method	ELECTRON MICROSCOPY 3.02 Å
Organisms	Homo sapiens Vicugna pacos
Macromolecule	Isoform 2 of Ceramide synthase 6 (protein) Nanobody-02 (protein)
Unique Ligands	NAG, PC1, PLM

1 to 9 of 9 Structures

Page 1 of 1

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

6H8R | pdb_00006h8r

CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND 2

6H8S | pdb_00006h8s

CRYSTAL STRUCTURE OF THE MOUSE PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND BI-0314

6ZLE | pdb_00006zle

Solution structure of unliganded MLKL executioner domain

6ZPR | pdb_00006zpr

Solution structure of MLKL executioner domain in complex with a covalent inhibitor

6ZVO | pdb_00006zvo

Crystal structure of unliganded MLKL executioner domain

6ZZ1 | pdb_00006zz1

Crystal structure of MLKL executioner domain in complex with a covalent inhibitor

8QZ6 | pdb_00008qz6

Structure of human ceramide synthase 6 (CerS6) bound to C16:0

8QZ7 | pdb_00008qz7

Structure of human ceramide synthase 6 (CerS6) in complex with N-palmitoyl fumonisin B1

9EOT | pdb_00009eot

Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

6H8R | pdb_00006h8r

6H8S | pdb_00006h8s

6ZLE | pdb_00006zle

6ZPR | pdb_00006zpr

6ZVO | pdb_00006zvo

6ZZ1 | pdb_00006zz1

8QZ6 | pdb_00008qz6

8QZ7 | pdb_00008qz7

9EOT | pdb_00009eot