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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Webb, T.R."

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Search Summary

This query matches 49 Structures.

Refinements

Structure Determination Methodology

experimental (49)

Scientific Name of Source Organism

	Influenza A virus (A/California/04/2009(H1N1)) (36)
	Influenza A virus (A/Viet Nam/1203/2004(H5N1)) (7)
	Influenza A virus (6)
	Influenza A virus (A/Luxembourg/43/2009(H1N1)) (4)
	synthetic construct (4)

Taxonomy

	Riboviria (49)
	other sequences (4)

Experimental Method

X-RAY DIFFRACTION (49)

Polymer Entity Type

	Protein (49)
	DNA (3)
	RNA (1)

Refinement Resolution (Å)

	1.5 - 2.0 (6)
	2.0 - 2.5 (40)
	2.5 - 3.0 (3)

Release Date

	2010 - 2014 (7)
	2015 - 2019 (36)
	2020 - 2024 (6)

Enzyme Classification Name

Hydrolases (43)

Symmetry Type

	Asymmetric (47)
	Cyclic (9)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (45)
	Artifacts (36)

AllSelected

1 to 25 of 49 Structures

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4E5E \| pdb_00004e5e	Download File View File

Crystal structure of avian influenza virus PAn Apo

DuBois, R.M., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.048 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	MN, SO4

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4E5F \| pdb_00004e5f	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 1

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.392 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	0N7, MN, SO4

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4E5G \| pdb_00004e5g	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 2

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.647 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	MN, SO4, XI7

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4E5H \| pdb_00004e5h	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 3

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.158 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	0N8, MN, SO4

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4E5I \| pdb_00004e5i	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 4

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.944 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	0N9, MN, SO4

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4E5J \| pdb_00004e5j	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 5

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	581, MN, SO4

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4E5L \| pdb_00004e5l	Download File View File

Crystal structure of avian influenza virus PAn bound to compound 6

DuBois, R.M., Slavish, P.J., Webb, T.R., White, S.W.

(2012) PLoS Pathog 8: e1002830-e1002830

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.469 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Polymerase protein PA (protein)
Unique Ligands	DBH, MN, SO4

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5CCY \| pdb_00005ccy	Download File View File

2009 H1N1 PA endonuclease in complex with dTMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, TMP

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5CGV \| pdb_00005cgv	Download File View File

2009 H1N1 PA endonuclease in complex with L-742,001

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-23
Method	X-RAY DIFFRACTION 2.17 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	0N8, GOL, MN

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5CL0 \| pdb_00005cl0	Download File View File

2009 H1N1 PA endonuclease in complex with rUMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.22 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, U5P

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5CZN \| pdb_00005czn	Download File View File

2009 H1N1 PA endonuclease mutant E119D

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 1.98 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, SO4

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5D2O \| pdb_00005d2o	Download File View File

2009 H1N1 PA endonuclease mutant F105S

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN

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5D42 \| pdb_00005d42	Download File View File

2009 H1N1 PA endonuclease mutant F105S in complex with dTMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, TMP

Explore in 3D

5D4G \| pdb_00005d4g	Download File View File

2009 H1N1 PA endonuclease mutant F105S in complex with rUMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-23
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, U5P

Explore in 3D

5D8U \| pdb_00005d8u	Download File View File

2009 H1N1 PA endonuclease mutant E119D in complex with L-742,001

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	0N8, MN

Explore in 3D

5D9J \| pdb_00005d9j	Download File View File

2009 H1N1 PA endonuclease mutant F105S in complex with L-742,001

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	0N8, MN

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5DBS \| pdb_00005dbs	Download File View File

2009 H1N1 PA endonuclease mutant E119D in complex with dTMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-23
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, SO4, TMP

Explore in 3D

5DEB \| pdb_00005deb	Download File View File

2009 H1N1 PA endonuclease mutant E119D in complex with rUMP

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.14 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN, U5P

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5DES \| pdb_00005des	Download File View File

2009 H1N1 PA endonuclease domain

Kumar, G., White, S.W.

(2016) Proc Natl Acad Sci U S A 113: 3669-3674

Released	2016-03-16
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	MN

Explore in 3D

5W3I \| pdb_00005w3i	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6e (SRI-29685)

Kumar, G., White, S.W.

(2017) Sci Rep 7: 17139-17139

Released	2017-12-27
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	GOL, GY5, MN

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5W44 \| pdb_00005w44	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 7a (SRI-29770)

Kumar, G., White, S.W.

(2017) Sci Rep 7: 17139-17139

Released	2018-01-10
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	GY6, MG, MN, NA

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5W73 \| pdb_00005w73	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9f (SRI-29835)

Kumar, G., White, S.

(2017) Sci Rep 7: 17139-17139

Released	2018-01-17
Method	X-RAY DIFFRACTION 2.202 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	GY9, MN, SO4

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5W7U \| pdb_00005w7u	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 8f (SRI-29928)

Kumar, G., White, S.

(2017) Sci Rep 7: 17139-17139

Released	2017-12-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	GY8, MN

Explore in 3D

5W92 \| pdb_00005w92	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-30049

Kumar, G., White, S.

(2017) Sci Rep 7: 17139-17139

Released	2018-02-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	9HD, KU0, MN

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5W9G \| pdb_00005w9g	Download File View File

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9k (SRI-30023)

Kumar, G., White, S.

(2017) Sci Rep 7: 17139-17139

Released	2017-12-27
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Influenza A virus (A/California/04/2009(H1N1))
Macromolecule	Polymerase acidic protein (protein)
Unique Ligands	CL, KU2, MN, SO4

1 to 25 of 49 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

4E5E | pdb_00004e5e

4E5F | pdb_00004e5f

4E5G | pdb_00004e5g

4E5H | pdb_00004e5h

4E5I | pdb_00004e5i

4E5J | pdb_00004e5j

4E5L | pdb_00004e5l

5CCY | pdb_00005ccy

5CGV | pdb_00005cgv

5CL0 | pdb_00005cl0

5CZN | pdb_00005czn

5D2O | pdb_00005d2o

5D42 | pdb_00005d42

5D4G | pdb_00005d4g

5D8U | pdb_00005d8u

5D9J | pdb_00005d9j

5DBS | pdb_00005dbs

5DEB | pdb_00005deb

5DES | pdb_00005des

5W3I | pdb_00005w3i

5W44 | pdb_00005w44

5W73 | pdb_00005w73

5W7U | pdb_00005w7u

5W92 | pdb_00005w92

5W9G | pdb_00005w9g