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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Yanez, E."

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Search Summary

This query matches 8 Structures.

Refinements

Structure Determination Methodology

experimental (8)

Scientific Name of Source Organism

Homo sapiens (8)

Taxonomy

Eukaryota (8)

Experimental Method

X-RAY DIFFRACTION (8)

Polymer Entity Type

Protein (8)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (6)
	2.5 - 3.0 (1)

Release Date

	2010 - 2014 (1)
	2015 - 2019 (7)

Enzyme Classification Name

Transferases (1)

Symmetry Type

	Asymmetric (8)
	Cyclic (5)

SCOP Classification

	Membrane and cell surface proteins and peptides (7)
	Alpha and beta proteins (a+b) (1)

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1 to 8 of 8 Structures

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Explore in 3D

3QQU \| pdb_00003qqu	Download File View File

Cocrystal structure of unphosphorylated igf with pyrimidine 8

Huang, X.

(2011) Bioorg Med Chem Lett 21: 2394-2399

Released	2011-04-20
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Insulin-like growth factor 1 receptor (protein)
Unique Ligands	01P

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6UD2 \| pdb_00006ud2	Download File View File

co-crystal structure of compound 1 bound to human Mcl-1

Huang, X., Whittington, D.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-04
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q4D

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6UDI \| pdb_00006udi	Download File View File

X-ray co-crystal structure of compound 20 with Mcl-1

Huang, X., Whittington, D.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-04
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q4S

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6UDT \| pdb_00006udt	Download File View File

X-ray co-crystal structure of compound 10 bound to human Mcl-1

Huang, X., Whittington, D.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-04
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q4V

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6UDU \| pdb_00006udu	Download File View File

X-ray co-crystal structure of compound 8 bound to human Mcl-1

Huang, X., Whittington, D.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-04
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q4Y

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6UDV \| pdb_00006udv	Download File View File

X-ray co-crystal structure of compound 3 bound to human Mcl-1

Huang, X., Whittington, D.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-04
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q51

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6UDX \| pdb_00006udx	Download File View File

X-ray co-crystal structure of compound 7 with Mcl-1

Huang, X.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-11
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q57

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6UDY \| pdb_00006udy	Download File View File

X-ray co-crystal structure of compound 5 with Mcl-1

Huang, X.

(2019) J Med Chem 62: 10258-10271

Released	2019-12-11
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	Q54

1 to 8 of 8 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

3QQU | pdb_00003qqu

Cocrystal structure of unphosphorylated igf with pyrimidine 8

6UD2 | pdb_00006ud2

co-crystal structure of compound 1 bound to human Mcl-1

6UDI | pdb_00006udi

X-ray co-crystal structure of compound 20 with Mcl-1

6UDT | pdb_00006udt

X-ray co-crystal structure of compound 10 bound to human Mcl-1

6UDU | pdb_00006udu

X-ray co-crystal structure of compound 8 bound to human Mcl-1

6UDV | pdb_00006udv

X-ray co-crystal structure of compound 3 bound to human Mcl-1

6UDX | pdb_00006udx

X-ray co-crystal structure of compound 7 with Mcl-1

6UDY | pdb_00006udy

X-ray co-crystal structure of compound 5 with Mcl-1

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

3QQU | pdb_00003qqu

6UD2 | pdb_00006ud2

6UDI | pdb_00006udi

6UDT | pdb_00006udt

6UDU | pdb_00006udu

6UDV | pdb_00006udv

6UDX | pdb_00006udx

6UDY | pdb_00006udy