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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "BMP2"

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Search Summary

This query matches 12 Structures.

Refinements

Structure Determination Methodology

experimental (12)

Scientific Name of Source Organism

	Homo sapiens (12)
	Mus musculus (2)
	Danio rerio (1)

Taxonomy

Eukaryota (12)

Experimental Method

X-RAY DIFFRACTION (12)

Polymer Entity Type

Protein (12)

Refinement Resolution (Å)

	1.5 - 2.0 (3)
	2.0 - 2.5 (2)
	2.5 - 3.0 (6)
	3.0 - 3.5 (1)

Release Date

	2005 - 2009 (7)
	2010 - 2014 (1)
	2015 - 2019 (2)
	2020 - 2024 (2)

Enzyme Classification Name

Transferases (6)

Symmetry Type

	Cyclic (10)
	Asymmetric (3)

SCOP Classification

Small proteins (10)

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1 to 12 of 12 Structures

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2GOO \| pdb_00002goo	Download File View File

Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD

Allendorph, G.P., Choe, S.

(2006) Proc Natl Acad Sci U S A 103: 7643-7648

Released	2006-05-09
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Activin receptor type 2A (protein) Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)
Unique Ligands	NDG

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2H62 \| pdb_00002h62	Download File View File

Crystal structure of a ternary ligand-receptor complex of BMP-2

Mueller, T.D.

(2007) BMC Struct Biol 7: 6-6

Released	2007-04-10
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Acvr2b protein (protein) Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)

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2H64 \| pdb_00002h64	Download File View File

Crystal structure of a ternary ligand-receptor complex of BMP-2

Mueller, T.D., Sebald, W., Weber, D.

(2007) BMC Struct Biol 7: 6-6

Released	2007-04-10
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Acvr2b protein (protein) Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)

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2QJ9 \| pdb_00002qj9	Download File View File

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1

Kotzsch, A., Mueller, T.D.

(2008) J Biological Chem 283: 5876-5887

Released	2008-01-15
Method	X-RAY DIFFRACTION 2.44 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)

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2QJA \| pdb_00002qja	Download File View File

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12

Kotzsch, A., Mueller, T.D.

(2008) J Biological Chem 283: 5876-5887

Released	2008-01-15
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)

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2QJB \| pdb_00002qjb	Download File View File

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB

Kotzsch, A., Mueller, T.D.

(2008) J Biological Chem 283: 5876-5887

Released	2008-01-15
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Bone morphogenetic protein receptor type IA (protein)
Unique Ligands	CL

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3BK3 \| pdb_00003bk3	Download File View File

Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2

Mueller, T.D., Sebald, W., Zhang, J.-L.

(2008) Dev Cell 14: 739-750

Released	2008-05-27
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Danio rerio Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Crossveinless 2 (protein)

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4N1D \| pdb_00004n1d	Download File View File

Nodal/BMP2 chimera NB250

Esquivies, L.

(2014) J Biological Chem 289: 1788-1797

Released	2013-12-04
Method	X-RAY DIFFRACTION 1.912 Å
Organisms	Homo sapiens
Macromolecule	Nodal/BMP2 chimera protein (protein)

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6OML \| pdb_00006oml	Download File View File

Human BMP chimera BV261

Seeherman, H., Juo, Z.S.

(2019) Sci Transl Med 11:

Released	2019-05-15
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 and Bone morphogenetic protein 6 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, MAN, NAG

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6OMN \| pdb_00006omn	Download File View File

Glycosylated BMP2 homodimer

Juo, Z.S., Seeherman, H.

(2019) Sci Transl Med 11:

Released	2019-05-08
Method	X-RAY DIFFRACTION 2.68 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein)
Unique branched monosaccharides	BMA, MAN, NAG

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7AG0 \| pdb_00007ag0	Download File View File

Complex between the bone morphogenetic protein 2 and its antagonist Noggin

Robert, C., Bruck, F., Herman, R., Vandevenne, M., Filee, P., Kerff, F., Matagne, A.

(2023) J Biological Chem 299: 102892-102892

Released	2022-04-13
Method	X-RAY DIFFRACTION 3.104 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Noggin (protein)
Unique Ligands	GOL

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8E3G \| pdb_00008e3g	Download File View File

BMP2/GDF5 heterodimer

Gipson, G.R., Nolan, K.T., Thompson, T.B.

(2023) BMC Biol 21: 16-16

Released	2023-02-15
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Bone morphogenetic protein 2 (protein) Growth/differentiation factor 5 (protein)
Unique Ligands	GOL

1 to 12 of 12 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

2GOO | pdb_00002goo

Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD

2H62 | pdb_00002h62

Crystal structure of a ternary ligand-receptor complex of BMP-2

2H64 | pdb_00002h64

Crystal structure of a ternary ligand-receptor complex of BMP-2

2QJ9 | pdb_00002qj9

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1

2QJA | pdb_00002qja

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12

2QJB | pdb_00002qjb

Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB

3BK3 | pdb_00003bk3

Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2

4N1D | pdb_00004n1d

Nodal/BMP2 chimera NB250

6OML | pdb_00006oml

Human BMP chimera BV261

6OMN | pdb_00006omn

Glycosylated BMP2 homodimer

7AG0 | pdb_00007ag0

Complex between the bone morphogenetic protein 2 and its antagonist Noggin

8E3G | pdb_00008e3g

BMP2/GDF5 heterodimer

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2GOO | pdb_00002goo

2H62 | pdb_00002h62

2H64 | pdb_00002h64

2QJ9 | pdb_00002qj9

2QJA | pdb_00002qja

2QJB | pdb_00002qjb

3BK3 | pdb_00003bk3

4N1D | pdb_00004n1d

6OML | pdb_00006oml

6OMN | pdb_00006omn

7AG0 | pdb_00007ag0

8E3G | pdb_00008e3g