RCSB PDB: Search

2KU3 \| pdb_00002ku3	Download File View File

Solution structure of BRD1 PHD1 finger

Qin, S., Zhang, J., Wu, J., Shi, Y.

To be published

Released	2011-02-16
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	ZN

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2L43 \| pdb_00002l43	Download File View File

Structural basis for histone code recognition by BRPF2-PHD1 finger

Qin, S., Zhang, J., Wu, J., Shi, Y.

To be published

Released	2011-08-31
Method	SOLUTION NMR
Organisms	Homo sapiens synthetic construct
Macromolecule	Histone H3.3,LINKER,Bromodomain-containing protein 1 (protein)
Unique Ligands	ZN

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2LQ6 \| pdb_00002lq6	Download File View File

Solution structure of BRD1 PHD2 finger

Liu, L., Wu, J.

(2012) J Struct Biol 180: 165-173

Released	2012-10-24
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	ZN

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3LYI \| pdb_00003lyi	Download File View File

PWWP Domain of Human Bromodomain-Containing Protein 1

Lam, R., Zeng, H., Ni, S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Wu, H., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e18919-e18919

Released	2010-03-16
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	OCS

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3RCW \| pdb_00003rcw	Download File View File

Crystal Structure of the bromodomain of human BRD1

Filippakopoulos, P., Keates, T., Picaud, S., Felletar, I., Pike, A.C.W., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)

(2012) Cell 149: 214-231

Released	2011-06-01
Method	X-RAY DIFFRACTION 2.21 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	ACT, EDO, MB3

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4Z02 \| pdb_00004z02	Download File View File

Crystal structure of BRD1 in complex with Isoquinoline-3-carboxylic acid

DONG, A., IQBAL, A., WALKER, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)

To be published

Released	2015-04-22
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	4K8, EDO, UNX

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5FG6 \| pdb_00005fg6	Download File View File

Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe

Tallant, C., Owen, D.R., Gerstenberger, B.S., Savitsky, P., Chaikuad, A., Fedorov, O., Nunez-Alonso, G., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Muller, S., Knapp, S.

To be published

Released	2016-02-03
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	5XE, EDO, NI, PO4

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5GK9 \| pdb_00005gk9	Download File View File

Crystal structure of human HBO1 in complex with BRPF2

Tao, Y., Zhu, J., Xu, S., Ding, J.

(2017) Nucleic Acids Res 45: 5707-5719

Released	2017-03-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	BRD1 protein (protein) Histone acetyltransferase KAT7 (protein)
Unique Ligands	ACO, ZN

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5N49 \| pdb_00005n49	Download File View File

BRPF2 in complex with Compound 7

Bouche, L., Christ, C.D., Siegel, S., Fernandez-Montalvan, A.E., Holton, S.J., Fedorov, O., ter Laak, A., Sugawara, T., Stoeckigt, D., Tallant, C., Bennett, J., Monteiro, O., Saez, L.D., Siejka, P., Meier, J., Puetter, V., Weiske, J., Mueller, S., Huber, K.V.M., Hartung, I.V., Haendler, B.

(2017) J Med Chem 60: 4002-4022

Released	2017-05-03
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8LW

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5PNX \| pdb_00005pnx	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10128a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.47 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	EDO, M3I, NA

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5PNY \| pdb_00005pny	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10174a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.479 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8S1, EDO, NA

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5PNZ \| pdb_00005pnz	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10162a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.557 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8S4, EDO, NA

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5PO0 \| pdb_00005po0	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10146a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.458 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8S7, EDO, NA

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5PO1 \| pdb_00005po1	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10152a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.517 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SA, EDO, NA

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5PO2 \| pdb_00005po2	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10132a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.67 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SD, EDO, NA

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5PO3 \| pdb_00005po3	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10164a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.699 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SG, EDO, NA

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5PO4 \| pdb_00005po4	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10170a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.487 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SJ, EDO, NA

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5PO5 \| pdb_00005po5	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10192a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.439 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SM, EDO, NA

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5PO6 \| pdb_00005po6	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10157a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SS, EDO, NA

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5PO7 \| pdb_00005po7	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N11083a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SV, EDO, NA

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5PO8 \| pdb_00005po8	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N07808b

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8SY, EDO, NA

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5PO9 \| pdb_00005po9	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N07950b

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 2.116 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8T7, EDO, NA

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5POA \| pdb_00005poa	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10186a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.62 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8TA, EDO, NA

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5POB \| pdb_00005pob	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with E13683b

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.779 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8TD, EDO, NA

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5POC \| pdb_00005poc	Download File View File

PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N11081a

Pearce, N.M., Krojer, T., Talon, R., Bradley, A.R., Fairhead, M., Sethi, R., Wright, N., MacLean, E., Collins, P., Brandao-Neto, J., Douangamath, A., Renjie, Z., Dias, A., Ng, J., Brennan, P.E., Cox, O., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.

(2017) Nat Commun 8: 15123-15123

Released	2017-03-15
Method	X-RAY DIFFRACTION 1.478 Å
Organisms	Homo sapiens
Macromolecule	Bromodomain-containing protein 1 (protein)
Unique Ligands	8TG, EDO, NA

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2KU3 | pdb_00002ku3

2L43 | pdb_00002l43

2LQ6 | pdb_00002lq6

3LYI | pdb_00003lyi

3RCW | pdb_00003rcw

4Z02 | pdb_00004z02

5FG6 | pdb_00005fg6

5GK9 | pdb_00005gk9

5N49 | pdb_00005n49

5PNX | pdb_00005pnx

5PNY | pdb_00005pny

5PNZ | pdb_00005pnz

5PO0 | pdb_00005po0

5PO1 | pdb_00005po1

5PO2 | pdb_00005po2

5PO3 | pdb_00005po3

5PO4 | pdb_00005po4

5PO5 | pdb_00005po5

5PO6 | pdb_00005po6

5PO7 | pdb_00005po7

5PO8 | pdb_00005po8

5PO9 | pdb_00005po9

5POA | pdb_00005poa

5POB | pdb_00005pob

5POC | pdb_00005poc