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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "HBA2"

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Search Summary

This query matches 41 Structures.

Refinements

Structure Determination Methodology

experimental (41)

Scientific Name of Source Organism

	Homo sapiens (41)
	Trypanosoma brucei brucei (1)
	Trypanosoma congolense (1)

Taxonomy

Eukaryota (41)

Experimental Method

	X-RAY DIFFRACTION (36)
	ELECTRON MICROSCOPY (3)
	NEUTRON DIFFRACTION (1)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (41)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (19)
	2.0 - 2.5 (12)
	2.5 - 3.0 (2)
	3.0 - 3.5 (4)
	3.5 - 4.0 (1)

Release Date

	1980 - 1984 (1)
	2005 - 2009 (3)
	2010 - 2014 (16)
	2015 - 2019 (6)
	2020 - 2024 (14)
	2025 - 2029 (1)

Symmetry Type

	Cyclic (36)
	Asymmetric (5)

SCOP Classification

	All alpha proteins (28)
	Artifacts (1)

AllSelected

1 to 25 of 41 Structures

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Explore in 3D

2DXM \| pdb_00002dxm	Download File View File

Neutron Structure Analysis of Deoxy Human Hemoglobin

Morimoto, Y.

(2007) J Am Chem Soc 129: 14840-14841

Released	2007-12-04
Method	NEUTRON DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM

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2M6Z \| pdb_00002m6z	Download File View File

Refined solution structure of Human Adult Hemoglobin in the Carbonmonoxy Form

Fan, J.S., Yang, D., Choy, W.Y.

(2013) Biochemistry 52: 5809-5820

Released	2013-09-18
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM

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3DUT \| pdb_00003dut	Download File View File

The high salt (phosphate) crystal structure of deoxy hemoglobin E (GLU26LYS) at physiological pH (pH 7.35)

Malashkevich, V.N., Balazs, T.C., Almo, S.C., Hirsch, R.E.

To be published

Released	2009-08-04
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, PO4

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3IA3 \| pdb_00003ia3	Download File View File

A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin

Feng, L., Jeffrey, P.D., Shi, Y.

(2009) J Biological Chem 284: 29462-29469

Released	2009-07-28
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	Alpha-hemoglobin-stabilizing protein (protein) Hemoglobin subunit alpha (protein)
Unique Ligands	HEM

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3NL7 \| pdb_00003nl7	Download File View File

Human Hemoglobin A mutant beta H63W carbonmonoxy-form

Birukou, I., Soman, J., Olson, J.S.

(2011) J Biological Chem 286: 10515-10529

Released	2010-07-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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3NMM \| pdb_00003nmm	Download File View File

Human Hemoglobin A mutant alpha H58W deoxy-form

Birukou, I., Soman, J., Olson, J.S.

(2011) J Biological Chem 286: 10515-10529

Released	2010-07-14
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, SO4

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3QJB \| pdb_00003qjb	Download File View File

Human Hemoglobin A Mutant Alpha H58L Carbonmonoxy-Form

Birukou, I., Soman, J., Olson, J.S.

Thesis

Released	2011-02-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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3QJC \| pdb_00003qjc	Download File View File

Human Hemoglobin A Mutant Beta H63L Carbonmonoxy-Form

Birukou, I., Soman, J., Olson, J.S.

Thesis

Released	2011-02-16
Method	X-RAY DIFFRACTION 2.001 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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3QJD \| pdb_00003qjd	Download File View File

Human Hemoglobin A Mutant Alpha H58L Deoxy-Form

Birukou, I., Soman, J., Olson, J.S.

Thesis

Released	2011-02-16
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, SO4

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3QJE \| pdb_00003qje	Download File View File

Human Hemoglobin A Mutant Beta H63L Deoxy-Form

Birukou, I., Soman, J., Olson, J.S.

Thesis

Released	2011-02-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, SO4

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3S65 \| pdb_00003s65	Download File View File

Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Lys) in the R2 quaternary structures

Shibayama, N., Sugiyama, K., Park, S.Y.

To be published

Released	2011-08-03
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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3S66 \| pdb_00003s66	Download File View File

Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Lys) in the R quaternary structures

Shibayama, N., Sugiyama, K., Park, S.Y.

To be published

Released	2011-08-03
Method	X-RAY DIFFRACTION 1.401 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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4HHB \| pdb_00004hhb	Download File View File

THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION

Fermi, G., Perutz, M.F.

(1984) J Mol Biology 175: 159-174

Released	1984-07-17
Method	X-RAY DIFFRACTION 1.74 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, PO4

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4MQC \| pdb_00004mqc	Download File View File

Carbonmonoxy Structure of Hemoglobin Evans alphaV62Mbetawt

Soman, J., Olson, J.S.

To be published

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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4MQG \| pdb_00004mqg	Download File View File

Structure of Carbonmonoxy Adult Hemoglobin Bristol-Alesha alphawtbetaV67M

Soman, J., Olson, J.S.

To be published

Released	2013-10-02
Method	X-RAY DIFFRACTION 1.68 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM

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4MQH \| pdb_00004mqh	Download File View File

Structure of Aquomet Hemoglobin Evans alphaV62Mbetawt

Soman, J., Olson, J.S.

To be published

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM

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4MQI \| pdb_00004mqi	Download File View File

Structure of Aquomet Hemoglobin Bristol-Alesha alphawtbetaV67M

Soman, J., Olson, J.S.

To be published

Released	2013-10-02
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM

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4MQJ \| pdb_00004mqj	Download File View File

Structure of Wild-type Fetal Human Hemoglobin HbF

Soman, J., Olson, J.S.

To be published

Released	2013-10-02
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit gamma-2 (protein)
Unique Ligands	CMO, HEM, OXY

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4MQK \| pdb_00004mqk	Download File View File

Carbonmonoxy Structure of the Human Fetal Hemoglobin Mutant HbF Toms River alphawtgammaV67M

Soman, J., Olson, J.S.

To be published

Released	2013-10-30
Method	X-RAY DIFFRACTION 2.242 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit gamma-2 (protein)
Unique Ligands	CMO, HEM

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4X0L \| pdb_00004x0l	Download File View File

Human haptoglobin-haemoglobin complex

Lane-Serff, H., MacGregor, P., Lowe, E.D., Carrington, M., Higgins, M.K.

(2014) Elife 3: e05553-e05553

Released	2014-12-24
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Haptoglobin (protein) Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CAC, GOL, HEM, OXY, SO4
Unique branched monosaccharides	FUC, NAG

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5E6E \| pdb_00005e6e	Download File View File

Crystal Structure of Carbonmonoxy Sickle Hemoglobin in R-State Conformation

Safo, M.K., Ahmed, M.H.

(2016) J Struct Biol 194: 446-450

Released	2015-10-28
Method	X-RAY DIFFRACTION 1.76 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	CMO, HEM, MBN, PO4

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5HU6 \| pdb_00005hu6	Download File View File

Structure of the T. brucei haptoglobin-haemoglobin receptor bound to human haptolgobin-haemoglobin

Lane-Serff, H., Higgins, M.K.

(2014) Elife 3: e05553

Released	2016-03-02
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Trypanosoma brucei brucei
Macromolecule	Haptoglobin (protein) Haptoglobin-hemoglobin receptor (protein) Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, NAG, OXY

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5JDO \| pdb_00005jdo	Download File View File

T. congolense haptoglobin-haemoglobin receptor in complex with haemoglobin

Lane-Serff, H., Higgins, M.K.

(2016) Elife 5:

Released	2016-04-27
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens Trypanosoma congolense
Macromolecule	Unique protein chains: 6
Unique Ligands	HEM, OXY

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5KDQ \| pdb_00005kdq	Download File View File

Deoxyhemoglobin in Complex with an Aryloxyalkanoic acid

Ahmed, M.H., Omar, A.M., Safo, M.K.

(2016) Molecules 21:

Released	2016-06-22
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM, KOH, PO4

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5NI1 \| pdb_00005ni1	Download File View File

CryoEM structure of haemoglobin at 3.2 A determined with the Volta phase plate

Khoshouei, M., Radjainia, M., Bunker, R., Baumeister, W., Danev, R.

(2017) Nat Commun 8: 16099-16099

Released	2017-04-12
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens
Macromolecule	Hemoglobin subunit alpha (protein) Hemoglobin subunit beta (protein)
Unique Ligands	HEM

1 to 25 of 41 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Symmetry Type

SCOP Classification

2DXM | pdb_00002dxm

2M6Z | pdb_00002m6z

3DUT | pdb_00003dut

3IA3 | pdb_00003ia3

3NL7 | pdb_00003nl7

3NMM | pdb_00003nmm

3QJB | pdb_00003qjb

3QJC | pdb_00003qjc

3QJD | pdb_00003qjd

3QJE | pdb_00003qje

3S65 | pdb_00003s65

3S66 | pdb_00003s66

4HHB | pdb_00004hhb

4MQC | pdb_00004mqc

4MQG | pdb_00004mqg

4MQH | pdb_00004mqh

4MQI | pdb_00004mqi

4MQJ | pdb_00004mqj

4MQK | pdb_00004mqk

4X0L | pdb_00004x0l

5E6E | pdb_00005e6e

5HU6 | pdb_00005hu6

5JDO | pdb_00005jdo

5KDQ | pdb_00005kdq

5NI1 | pdb_00005ni1