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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "MUTL"

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Search Summary

This query matches 26 Structures.

Refinements

Structure Determination Methodology

experimental (26)

Scientific Name of Source Organism

	Aquifex aeolicus VF5 (10)
	Escherichia coli K-12 (10)
	Bacillus subtilis (4)
	synthetic construct (2)
	DNA molecule (1)
	Escherichia coli (1)
	Escherichia coli O139:H28 str. E24377A (1)
	Neisseria gonorrhoeae FA 1090 (1)

Taxonomy

	Bacteria (26)
	other sequences (2)
	unclassified sequences (1)

Experimental Method

	X-RAY DIFFRACTION (23)
	ELECTRON MICROSCOPY (3)

Polymer Entity Type

	Protein (26)
	DNA (3)

Refinement Resolution (Å)

	1.0 - 1.5 (5)
	1.5 - 2.0 (4)
	2.0 - 2.5 (10)
	2.5 - 3.0 (2)
	3.0 - 3.5 (2)
	3.5 - 4.0 (1)
	> 4.5 (2)

Release Date

	1995 - 1999 (3)
	2000 - 2004 (4)
	2010 - 2014 (4)
	2015 - 2019 (6)
	2020 - 2024 (9)

Symmetry Type

	Cyclic (20)
	Asymmetric (6)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (7)
	Artifacts (5)

AllSelected

1 to 25 of 26 Structures

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1B62 \| pdb_00001b62	Download File View File

MUTL COMPLEXED WITH ADP

Wei, Y.

(1999) Cell 97: 85-97

Released	1999-04-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (MUTL) (protein)
Unique Ligands	ADP, MG

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1B63 \| pdb_00001b63	Download File View File

MUTL COMPLEXED WITH ADPNP

Yang, W.

(1999) Cell 97: 85-97

Released	1999-06-08
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli K-12
Macromolecule	MUTL (protein)
Unique Ligands	ANP, EDO, MG

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1BKN \| pdb_00001bkn	Download File View File

CRYSTAL STRUCTURE OF AN N-TERMINAL 40KD FRAGMENT OF E. COLI DNA MISMATCH REPAIR PROTEIN MUTL

Yang, W., Ban, C.

(1998) Cell 95: 541-552

Released	1999-05-11
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Escherichia coli K-12
Macromolecule	MUTL (protein)

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1NHH \| pdb_00001nhh	Download File View File

Crystal structure of N-terminal 40KD MutL protein (LN40) complex with ADPnP and one Rubidium

Hu, X., Machius, M., Yang, W.

(2003) FEBS Lett 544: 268-273

Released	2003-06-10
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Escherichia coli K-12
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	ANP, EDO, MG, RB

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1NHI \| pdb_00001nhi	Download File View File

Crystal structure of N-terminal 40KD MutL (LN40) complex with ADPnP and one potassium

Hu, X., Machius, M., Yang, W.

(2003) FEBS Lett 544: 268-273

Released	2003-06-10
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli K-12
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	ANP, EDO, K, MG

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1NHJ \| pdb_00001nhj	Download File View File

Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one sodium

Hu, X., Machius, M., Yang, W.

(2003) FEBS Lett 544: 268-273

Released	2003-06-10
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli K-12
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	ANP, MG, NA

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1X9Z \| pdb_00001x9z	Download File View File

Crystal structure of the MutL C-terminal domain

Guarne, A., Ramon-Maiques, S., Wolff, E.M., Ghirlando, R., Hu, X., Miller, J.H., Yang, W.

(2004) EMBO J 23: 4134-4145

Released	2004-10-26
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	CL, GOL, IPA, NA

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3GAB \| pdb_00003gab	Download File View File

C-terminal domain of Bacillus subtilis MutL crystal form I

Guarne, A., Pillon, M.C., Lorenowicz, J.J., Mitchell, R.R., Chung, Y.S., Friedhoff, P.

(2010) Mol Cell 39: 145-151

Released	2010-07-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bacillus subtilis
Macromolecule	DNA mismatch repair protein mutL (protein)

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3KDG \| pdb_00003kdg	Download File View File

C-terminal domain of Bacillus subtilis MutL crystal form II

Guarne, A., Pillon, M.C.

(2010) Mol Cell 39: 145-151

Released	2010-07-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bacillus subtilis
Macromolecule	DNA mismatch repair protein mutL (protein)

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3KDK \| pdb_00003kdk	Download File View File

Structure of the C-terminal domain of Bacillus subtilis MutL bound to Zn2+

Guarne, A., Pillon, M.C.

(2010) Mol Cell 39: 145-151

Released	2010-07-21
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Bacillus subtilis
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	ZN

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3NCV \| pdb_00003ncv	Download File View File

NgoL

Namadurai, S., Jain, D., Nair, D.T.

(2010) PLoS One 5: e13726-e13726

Released	2010-12-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Neisseria gonorrhoeae FA 1090
Macromolecule	DNA mismatch repair protein mutL (protein)

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5B42 \| pdb_00005b42	Download File View File

Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.

Fukui, K., Baba, S., Kumasaka, T., Yano, T.

(2016) J Biological Chem 291: 16990-17000

Released	2016-07-13
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	CD, PEG

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5X9Y \| pdb_00005x9y	Download File View File

Crystal structure of the ATPase domain from bacterial mismatch repair endonuclease Aquifex aeolicus MutL.

Fukui, K., Yano, T.

(2017) Biochim Biophys Acta 1865: 1178-1187

Released	2017-08-30
Method	X-RAY DIFFRACTION 3.443 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	PEG

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5Z41 \| pdb_00005z41	Download File View File

Aquifex aeolicus MutL endonuclease domain with a single zinc ion.

Fukui, K., Yano, T.

(2018) FEBS Lett 592: 1611-1619

Released	2018-04-25
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	MG, PEG, ZN

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5Z42 \| pdb_00005z42	Download File View File

Aquifex aeolicus MutL endonuclease domain with three zinc ions.

Fukui, K., Yano, T.

(2018) FEBS Lett 592: 1611-1619

Released	2018-04-25
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	CL, MG, NA, PEG, ZN

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6E8D \| pdb_00006e8d	Download File View File

Crystal structure of the Bacillus subtilis sliding clamp-MutL complex.

Guarne, A., Almawi, A.W.

(2019) Nucleic Acids Res 47: 4831-4842

Released	2019-05-01
Method	X-RAY DIFFRACTION 2.34 Å
Organisms	Bacillus subtilis
Macromolecule	Beta sliding clamp,DNA mismatch repair protein MutL (protein)
Unique Ligands	GOL

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6E8E \| pdb_00006e8e	Download File View File

Crystal structure of the Escherichia coli sliding clamp-MutL complex.

Guarne, A., Almawi, A.W.

(2019) Nucleic Acids Res 47: 4831-4842

Released	2019-05-01
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Escherichia coli K-12 Escherichia coli O139:H28 str. E24377A
Macromolecule	Beta sliding clamp,DNA mismatch repair protein MutL (protein)
Unique Ligands	GOL, SO4

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6LZI \| pdb_00006lzi	Download File View File

Aquifex aeolicus MutL ATPase domain complexed with ADP

Fukui, K., Izuhara, K., Yano, T.

(2020) J Biological Chem 295: 11643-11655

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.69105685009 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	ADP, MG, PEG

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6LZJ \| pdb_00006lzj	Download File View File

Aquifex aeolicus MutL ATPase domain complexed with AMPPCP

Fukui, K., Izuhara, K., Yano, T.

(2020) J Biological Chem 295: 11643-11655

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.72835563454 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	ACP, MG

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6LZK \| pdb_00006lzk	Download File View File

Aquifex aeolicus MutL ATPase domain with K252N mutation

Fukui, K., Izuhara, K., Yano, T.

(2020) J Biological Chem 295: 11643-11655

Released	2020-07-01
Method	X-RAY DIFFRACTION 3.1594962224 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	NA, PEG

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7AIB \| pdb_00007aib	Download File View File

MutS-MutL in clamp state

Fernandez-Leiro, R., Bhairosing-Kok, D., Sixma, T.K., Lamers, M.H.

(2021) Nat Struct Mol Biol 28: 373-381

Released	2021-03-31
Method	ELECTRON MICROSCOPY 4.7 Å
Organisms	Escherichia coli K-12 synthetic construct
Macromolecule	DNA mismatch repair protein MutL (protein) DNA mismatch repair protein MutS (protein) DNA (30-MER) (nucleic acid)
Unique Ligands	ANP

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7AIC \| pdb_00007aic	Download File View File

MutS-MutL in clamp state (kinked clamp domain)

Fernandez-Leiro, R., Bhairosing-Kok, D., Sixma, T.K., Lamers, M.H.

(2021) Nat Struct Mol Biol 28: 373-381

Released	2021-03-31
Method	ELECTRON MICROSCOPY 5 Å
Organisms	Escherichia coli K-12 synthetic construct
Macromolecule	DNA mismatch repair protein MutL (protein) DNA mismatch repair protein MutS (protein) DNA (30-MER) (nucleic acid)
Unique Ligands	ANP

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7P8V \| pdb_00007p8v	Download File View File

The structure of E. coli MutL bound to a 3' resected DNA end

Borsellini, A., Lamers, M.H.

(2022) Nucleic Acids Res 50: 6224-6234

Released	2022-06-29
Method	ELECTRON MICROSCOPY 3.6 Å
Organisms	DNA molecule Escherichia coli K-12
Macromolecule	DNA mismatch repair protein MutL (protein) Primer strand (nucleic acid) Template strand (nucleic acid)
Unique Ligands	ANP, MG

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8H1E \| pdb_00008h1e	Download File View File

Aquifex aeolicus MutL endonuclease domain complexed with manganese ions

Fukui, K., Yano, T.

(2023) Life Sci Alliance 6:

Released	2023-08-16
Method	X-RAY DIFFRACTION 1.22 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	MN, PEG

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8H1F \| pdb_00008h1f	Download File View File

Aquifex aeolicus MutL endonuclease domain complexed with zinc ions after soaking

Fukui, K., Yano, T.

(2023) Life Sci Alliance 6:

Released	2023-08-16
Method	X-RAY DIFFRACTION 1.22 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	DNA mismatch repair protein MutL (protein)
Unique Ligands	CL, PEG, ZN

1 to 25 of 26 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Symmetry Type

SCOP Classification

1B62 | pdb_00001b62

1B63 | pdb_00001b63

1BKN | pdb_00001bkn

1NHH | pdb_00001nhh

1NHI | pdb_00001nhi

1NHJ | pdb_00001nhj

1X9Z | pdb_00001x9z

3GAB | pdb_00003gab

3KDG | pdb_00003kdg

3KDK | pdb_00003kdk

3NCV | pdb_00003ncv

5B42 | pdb_00005b42

5X9Y | pdb_00005x9y

5Z41 | pdb_00005z41

5Z42 | pdb_00005z42

6E8D | pdb_00006e8d

6E8E | pdb_00006e8e

6LZI | pdb_00006lzi

6LZJ | pdb_00006lzj

6LZK | pdb_00006lzk

7AIB | pdb_00007aib

7AIC | pdb_00007aic

7P8V | pdb_00007p8v

8H1E | pdb_00008h1e

8H1F | pdb_00008h1f