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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "RBAP48"

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Search Summary

This query matches 41 Structures.

Refinements

Structure Determination Methodology

experimental (41)

Scientific Name of Source Organism

	Homo sapiens (41)
	Xenopus laevis (4)
	synthetic construct (3)
	Neogale vison (1)

Taxonomy

	Eukaryota (41)
	other sequences (3)

Experimental Method

	ELECTRON MICROSCOPY (21)
	X-RAY DIFFRACTION (20)

Polymer Entity Type

	Protein (41)
	DNA (5)
	RNA (2)

Refinement Resolution (Å)

	1.5 - 2.0 (3)
	2.0 - 2.5 (7)
	2.5 - 3.0 (9)
	3.0 - 3.5 (6)
	3.5 - 4.0 (9)
	4.0 - 4.5 (3)
	> 4.5 (4)

Release Date

	2005 - 2009 (1)
	2010 - 2014 (3)
	2015 - 2019 (12)
	2020 - 2024 (20)
	2025 - 2029 (5)

Enzyme Classification Name

	Transferases (19)
	Hydrolases (1)

Symmetry Type

	Asymmetric (37)
	Cyclic (4)

SCOP Classification

All beta proteins (3)

AllSelected

1 to 25 of 41 Structures

Page 1 of 2

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3GFC \| pdb_00003gfc	Download File View File

Crystal Structure of Histone-binding protein RBBP4

Amaya, M.F., Dong, A., Li, Z., He, H., Ni, S., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Bountra, C., Bochkarev, A., Min, J., Ouyang, H., Structural Genomics Consortium (SGC)

(2011) Protein Cell 2: 202-214

Released	2009-04-14
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein)

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4PBY \| pdb_00004pby	Download File View File

Structure of the human RbAp48-MTA1(656-686) complex

Murthy, A., Lejon, S., Alqarni, S.S.M., Silva, A.P.G., Watson, A.A., Mackay, J.P., Laue, E.D.

(2014) J Biological Chem 289: 21844

Released	2014-06-11
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Metastasis-associated protein MTA1 (protein)
Unique Ligands	IPA

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4PBZ \| pdb_00004pbz	Download File View File

Structure of the human RbAp48-MTA1(670-695) complex

Murthy, A., Pei, X.Y., Watson, A.A., Silva, A.P.G., Mackay, J.P., Laue, E.D.

(2014) J Biological Chem 289: 21844

Released	2014-06-11
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Metastasis-associated protein MTA1 (protein)

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4PC0 \| pdb_00004pc0	Download File View File

Structure of the human RbAp48-MTA1(670-711) complex

Alqarni, S.S.M., Silva, A.P.G., Mackay, J.P., Laue, E.D.

(2014) J Biological Chem 289: 21844

Released	2014-06-11
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Metastasis-associated protein MTA1 (protein)
Unique Ligands	CA, GOL

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4R7A \| pdb_00004r7a	Download File View File

Crystal Structure of RBBP4 bound to PHF6 peptide

Liu, Z., Li, F., Zhang, B., Li, S., Wu, J., Shi, Y.

(2015) J Biological Chem 290: 6630-6638

Released	2015-01-14
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) PHD finger protein 6 (protein)
Unique Ligands	GOL

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5VTB \| pdb_00005vtb	Download File View File

Crystal structure of RBBP4 bound to BCL11a peptide

Meagher, J.L., Stuckey, J.A.

(2018) J Biological Chem 293: 2125-2136

Released	2017-12-27
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	B-cell lymphoma/leukemia 11A (protein) Histone-binding protein RBBP4 (protein)
Unique Ligands	GOL

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5WAI \| pdb_00005wai	Download File View File

Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex

Chen, S., Jiao, L., Liu, X.

(2018) Mol Cell 69: 840-852.e5

Released	2018-03-14
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Neogale vison
Macromolecule	Histone-binding protein RBBP4 (protein) Jumonji, AT-rich interactive domain 2 (protein) Polycomb protein SUZ12 (protein) Zinc finger protein AEBP2 (protein)
Unique Ligands	ZN

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5WAK \| pdb_00005wak	Download File View File

Crystal Structure of a Suz12-Rbbp4 Binary Complex

Chen, S., Jiao, L., Liu, X.

(2018) Mol Cell 69: 840-852.e5

Released	2018-03-14
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Polycomb protein SUZ12 (protein)
Unique Ligands	ZN

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5XWR \| pdb_00005xwr	Download File View File

Crystal Structure of RBBP4-peptide complex

Jobichen, C., Lui, B.H., Daniel, G.T., Sivaraman, J.

(2018) Proc Natl Acad Sci U S A 115: E7119-E7128

Released	2018-07-11
Method	X-RAY DIFFRACTION 2.69 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE (protein)

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5XXQ \| pdb_00005xxq	Download File View File

Crystal structure of RBBP4: ZNF827 and its function in telomere

Sun, A., Shi, Y.

To be published

Released	2018-08-08
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Zinc finger protein 827 (protein)

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5Y1U \| pdb_00005y1u	Download File View File

Crystal structure of RBBP4 bound to AEBP2 RRK motif

Sun, A., Li, F., Wu, J., Shi, Y.

(2017) Protein Cell

Released	2018-04-18
Method	X-RAY DIFFRACTION 2.141 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Zinc finger protein AEBP2 (protein)
Unique Ligands	SO4

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6BW3 \| pdb_00006bw3	Download File View File

Crystal structure of RBBP4 in complex with PRDM3 N-terminal peptide

Ivanochko, D., Halabelian, L., Hutchinson, A., Seitova, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)

(2019) Nucleic Acids Res 47: 1225-1238

Released	2017-12-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) MDS1 and EVI1 complex locus protein MDS1 (protein)
Unique Ligands	UNX

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6BW4 \| pdb_00006bw4	Download File View File

Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide

Ivanochko, D., Halabelian, L., Hutchinson, A., Seitova, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)

(2019) Nucleic Acids Res 47: 1225-1238

Released	2017-12-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) PR domain zinc finger protein 16 (protein)
Unique Ligands	UNX

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6C23 \| pdb_00006c23	Download File View File

Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State

Kasinath, V., Faini, M., Poepsel, S., Reif, D., Feng, A., Stjepanovic, G., Aebersold, R., Nogales, E.

(2018) Science 359: 940-944

Released	2018-01-24
Method	ELECTRON MICROSCOPY 3.9 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 9

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6C24 \| pdb_00006c24	Download File View File

Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State

Kasinath, V., Faini, M., Poepsel, S., Reif, D., Feng, A., Stjepanovic, G., Aebersold, R., Nogales, E.

(2018) Science 359: 940-944

Released	2018-01-24
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 9

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6G16 \| pdb_00006g16	Download File View File

Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange

Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.

(2016) Elife 5: e13941-e13941

Released	2018-06-13
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Metastasis-associated protein MTA1 (protein)

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6NQ3 \| pdb_00006nq3	Download File View File

Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex

Chen, S., Jiao, L., Liu, X.

(2020) Mol Cell 77: 1265

Released	2020-01-29
Method	X-RAY DIFFRACTION 2.89 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) PHD finger protein 19 (protein) Polycomb protein SUZ12 (protein) Protein Jumonji (protein)
Unique Ligands	ZN

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6WKR \| pdb_00006wkr	Download File View File

PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome

Kasinath, V., Nogales, E., Beck, C., Sauer, P., Poepsel, S., Kosmatka, J., Faini, M., Toso, D., Aebersold, R.

(2021) Science 371:

Released	2021-02-03
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Homo sapiens Xenopus laevis
Macromolecule	Unique protein chains: 11 Unique nucleic acid chains: 1
Unique Ligands	MG, SAH, ZN

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6ZRC \| pdb_00006zrc	Download File View File

Structure of the human RBAP48 in complex with a macrocyclic peptide cyclized via a xylene linker attached to two cysteines

Vetter, I.R., Porfetye, A.T.

(2021) Angew Chem Int Ed Engl 60: 1813-1820

Released	2020-10-28
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) macrocyclic peptide based on residues 659-672 of the metastasis-associated protein MTA1 (protein)
Unique Ligands	PXY

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6ZRD \| pdb_00006zrd	Download File View File

STRUCTURE OF THE HUMAN RBAP48 in complex with a macrocyclic peptide cyclized via a xylene linker attached to two cysteines

Vetter, I.R., Porfetye, A.T.

(2021) Angew Chem Int Ed Engl 60: 1813-1820

Released	2020-12-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) macrocyclic peptide based on residues 659-672 of the metastasis-associated protein MTA1 (protein)
Unique Ligands	SEZ

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7AOA \| pdb_00007aoa	Download File View File

Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex

Millard, C.J., Fairall, L., Ragan, T.J., Savva, C.G., Schwabe, J.W.R.

(2020) Nucleic Acids Res 48: 12972-12982

Released	2020-11-11
Method	ELECTRON MICROSCOPY 19.4 Å
Organisms	Homo sapiens
Macromolecule	Histone deacetylase 1 (protein) Histone-binding protein RBBP4 (protein) Metastasis-associated protein MTA1 (protein) Methyl-CpG-binding domain protein 2 (protein)
Unique Ligands	IHP, K, ZN

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7KSO \| pdb_00007kso	Download File View File

Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2

Grau, D.J., Armache, K.J.

(2021) Nat Commun 12: 714-714

Released	2021-02-03
Method	ELECTRON MICROSCOPY 3.9 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 6
Unique Ligands	ZN

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7KSR \| pdb_00007ksr	Download File View File

PRC2:EZH1_A from a dimeric PRC2 bound to a nucleosome

Grau, D.J., Armache, K.J.

(2021) Nat Commun 12: 714-714

Released	2021-02-03
Method	ELECTRON MICROSCOPY 4.1 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Histone-lysine N-methyltransferase EZH1 (protein) Polycomb protein EED (protein) Polycomb protein SUZ12 (protein)
Unique Ligands	ZN

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7KTP \| pdb_00007ktp	Download File View File

PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome

Grau, D.J., Armache, K.J.

(2021) Nat Commun 12: 714-714

Released	2021-02-03
Method	ELECTRON MICROSCOPY 4.8 Å
Organisms	Homo sapiens
Macromolecule	Histone-binding protein RBBP4 (protein) Histone-lysine N-methyltransferase EZH1 (protein) Polycomb protein EED (protein) Polycomb protein SUZ12 (protein)
Unique Ligands	ZN