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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "COMPLEX (SERINE PROTEASE/INHIBITOR)"

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Search Summary

This query matches 25 Structures.

Refinements

Structure Determination Methodology

experimental (25)

Scientific Name of Source Organism

	Bos taurus (9)
	Homo sapiens (9)
	Hirudo medicinalis (7)
	Rattus norvegicus (6)
	Escherichia coli (5)
	Meleagris gallopavo (3)
	Streptomyces griseus (3)
	Sus scrofa (3)
	Rhodnius prolixus (2)
	Leptuca pugilator (1)

Taxonomy

	Eukaryota (25)
	Bacteria (8)
	Eukaryota (eukaryotes) (1)

Experimental Method

X-RAY DIFFRACTION (25)

Polymer Entity Type

Protein (25)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (7)
	2.0 - 2.5 (12)
	2.5 - 3.0 (3)
	3.0 - 3.5 (2)

Release Date

1995 - 1999 (25)

Enzyme Classification Name

Hydrolases (25)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (19)
	Cyclic (7)

SCOP Classification

	All beta proteins (25)
	Small proteins (14)

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1 to 25 of 25 Structures

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1AN1 \| pdb_00001an1	Download File View File

LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX

Priestle, J.P., Di Marco, S.

(1997) Structure 5: 1465-1474

Released	1998-07-01
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Hirudo medicinalis Sus scrofa
Macromolecule	TRYPSIN (protein) TRYPTASE INHIBITOR (protein)
Unique Ligands	CA

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1AZZ \| pdb_00001azz	Download File View File

FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN

Perona, J.J., Fletterick, R.J.

(1997) Biochemistry 36: 5381-5392

Released	1998-02-25
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli Leptuca pugilator
Macromolecule	COLLAGENASE (protein) ECOTIN (protein)

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1BTH \| pdb_00001bth	Download File View File

STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR

Van De Locht, A., Bode, W., Stubbs, M.T.

(1997) EMBO J 16: 2977-2984

Released	1997-12-24
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bos taurus
Macromolecule	BOVINE PANCREATIC TRYPSIN INHIBITOR (protein) THROMBIN (protein)

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1CA0 \| pdb_00001ca0	Download File View File

BOVINE CHYMOTRYPSIN COMPLEXED TO APPI

Scheidig, A.J., Kossiakoff, A.A.

(1997) Protein Sci 6: 1806-1824

Released	1997-07-23
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Bos taurus Homo sapiens
Macromolecule	BOVINE CHYMOTRYPSIN (protein) PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR (protein)

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1CBW \| pdb_00001cbw	Download File View File

BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI

Hynes, T.R., Scheidig, A.J., Kossiakoff, A.A.

(1997) Protein Sci 6: 1806-1824

Released	1997-07-23
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Bos taurus
Macromolecule	BOVINE CHYMOTRYPSIN (protein) BPTI (protein)
Unique Ligands	SO4

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1FLE \| pdb_00001fle	Download File View File

CRYSTAL STRUCTURE OF ELAFIN COMPLEXED WITH PORCINE PANCREATIC ELASTASE

Tsunemi, M., Matsuura, Y., Sakakibara, S., Katsube, Y.

(1996) Biochemistry 35: 11570-11576

Released	1997-01-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	ELAFIN (protein) ELASTASE (protein)

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1LHC \| pdb_00001lhc	Download File View File

HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BOROARG-OH

Weber, P.C., Lee, S.L., Lewandowski, F.A., Schadt, M.C., Chang, C.H., Kettner, C.A.

(1995) Biochemistry 34: 3750-3757

Released	1996-11-08
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	DP7

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1LHD \| pdb_00001lhd	Download File View File

HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BOROLYS-OH

Weber, P.C., Lee, S.L., Lewandowski, F.A., Schadt, M.C., Chang, C.H., Kettner, C.A.

(1995) Biochemistry 34: 3750-3757

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	DI2

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1LHE \| pdb_00001lhe	Download File View File

HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BORO-N-BUTYL-AMIDINO-GLYCINE-OH

Weber, P.C., Lee, S.L., Lewandowski, F.A., Schadt, M.C., Chang, C.H., Kettner, C.A.

(1995) Biochemistry 34: 3750-3757

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	DI3

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1LHF \| pdb_00001lhf	Download File View File

HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BORO-HOMOLYS-OH

Weber, P.C., Lee, S.L., Lewandowski, F.A., Schadt, M.C., Chang, C.H., Kettner, C.A.

(1995) Biochemistry 34: 3750-3757

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	DI4

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1LHG \| pdb_00001lhg	Download File View File

HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BOROORNITHINE-OH

Weber, P.C., Lee, S.L., Lewandowski, F.A., Schadt, M.C., Chang, C.H., Kettner, C.A.

(1995) Biochemistry 34: 3750-3757

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	DI5

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1SGP \| pdb_00001sgp	Download File View File

ALA 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B

Huang, K., James, M.N.G.

(1995) Protein Sci 4: 1985-1997

Released	1995-10-15
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Meleagris gallopavo Streptomyces griseus
Macromolecule	STREPTOMYCES GRISEUS PROTEINASE B (protein) TURKEY OVOMUCOID INHIBITOR (protein)
Unique Ligands	PO4

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1SGQ \| pdb_00001sgq	Download File View File

GLY 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B

Huang, K., James, M.N.G.

(1995) Protein Sci 4: 1985-1997

Released	1995-10-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Meleagris gallopavo Streptomyces griseus
Macromolecule	STREPTOMYCES GRISEUS PROTEINASE B (protein) TURKEY OVOMUCOID INHIBITOR (protein)
Unique Ligands	PO4

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1SGR \| pdb_00001sgr	Download File View File

LEU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B

Huang, K., James, M.N.G.

(1995) Protein Sci 4: 1985-1997

Released	1995-10-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Meleagris gallopavo Streptomyces griseus
Macromolecule	STREPTOMYCES GRISEUS PROTEINASE B (protein) TURKEY OVOMUCOID INHIBITOR (protein)
Unique Ligands	PO4

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1SLU \| pdb_00001slu	Download File View File

RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN

Brinen, L.S., Fletterick, R.J.

(1996) Biochemistry 35: 5999-6009

Released	1996-07-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Escherichia coli Rattus norvegicus
Macromolecule	ANIONIC TRYPSIN (protein) ECOTIN (protein)
Unique Ligands	ACT, CA

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1SLV \| pdb_00001slv	Download File View File

RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND

Brinen, L.S., Fletterick, R.J.

(1996) Biochemistry 35: 5999-6009

Released	1996-07-11
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli Rattus norvegicus
Macromolecule	ANIONIC TRYPSIN (protein) ECOTIN (protein)
Unique Ligands	ACT, CA, CU

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1SLW \| pdb_00001slw	Download File View File

RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; NICKEL-BOUND

Brinen, L.S., Fletterick, R.J.

(1996) Biochemistry 35: 5999-6009

Released	1996-07-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli Rattus norvegicus
Macromolecule	ANIONIC TRYPSIN (protein) ECOTIN (protein)
Unique Ligands	ACT, CA, NI

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1SLX \| pdb_00001slx	Download File View File

RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; ZINC-BOUND

Brinen, L.S., Fletterick, R.J.

(1996) Biochemistry 35: 5999-6009

Released	1996-07-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli Rattus norvegicus
Macromolecule	ANIONIC TRYPSIN (protein) ECOTIN (protein)
Unique Ligands	ACT, CA, ZN

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1TAW \| pdb_00001taw	Download File View File

BOVINE TRYPSIN COMPLEXED TO APPI

Hynes, T.R., Kossiakoff, A.A.

(1997) Protein Sci 6: 1806-1824

Released	1997-06-24
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus Homo sapiens
Macromolecule	PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR (protein) TRYPSIN (protein)
Unique Ligands	CA

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1TBQ \| pdb_00001tbq	Download File View File

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN

Van De Locht, A., Lamba, D., Bode, W.

(1995) EMBO J 14: 5149-5157

Released	1996-10-14
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Bos taurus Rhodnius prolixus
Macromolecule	RHODNIIN (protein) THROMBIN (protein)

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1TBR \| pdb_00001tbr	Download File View File

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN

Van De Locht, A., Lamba, D., Bode, W.

(1995) EMBO J 14: 5149-5157

Released	1996-10-14
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Bos taurus Rhodnius prolixus
Macromolecule	RHODNIIN (protein) THROMBIN (protein)

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1TFX \| pdb_00001tfx	Download File View File

COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN

Stubbs, M.T., Huber, R.

(1997) J Mol Biology 269: 395-407

Released	1998-01-21
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	TISSUE FACTOR PATHWAY INHIBITOR (protein) TRYPSIN (protein)
Unique Ligands	CA

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1VIT \| pdb_00001vit	Download File View File

THROMBIN:HIRUDIN 51-65 COMPLEX

Vitali, J., Edwards, B.F.P.

(1996) Acta Crystallogr D Biol Crystallogr 52: 453-464

Released	1997-04-21
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Bos taurus Hirudo medicinalis
Macromolecule	ALPHA THROMBIN (protein) EPSILON THROMBIN (protein) HIRUDIN (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

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3TGI \| pdb_00003tgi	Download File View File

WILD-TYPE RAT ANIONIC TRYPSIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)

Pasternak, A., Ringe, D., Hedstrom, L.

(1999) Protein Sci 8: 253-258

Released	1998-12-23
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus Rattus norvegicus
Macromolecule	BOVINE PANCREATIC TRYPSIN INHIBITOR (protein) TRYPSIN (protein)
Unique Ligands	CA, SO4

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3TGJ \| pdb_00003tgj	Download File View File

S195A TRYPSINOGEN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)

Pasternak, A., Ringe, D., Hedstrom, L.

(1999) Protein Sci 8: 253-258

Released	1998-12-23
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Bos taurus Rattus norvegicus
Macromolecule	BOVINE PANCREATIC TRYPSIN INHIBITOR (protein) TRYPSIN (protein)
Unique Ligands	CA, SO4

1 to 25 of 25 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1AN1 | pdb_00001an1

1AZZ | pdb_00001azz

1BTH | pdb_00001bth

1CA0 | pdb_00001ca0

1CBW | pdb_00001cbw

1FLE | pdb_00001fle

1LHC | pdb_00001lhc

1LHD | pdb_00001lhd

1LHE | pdb_00001lhe

1LHF | pdb_00001lhf

1LHG | pdb_00001lhg

1SGP | pdb_00001sgp

1SGQ | pdb_00001sgq

1SGR | pdb_00001sgr

1SLU | pdb_00001slu

1SLV | pdb_00001slv

1SLW | pdb_00001slw

1SLX | pdb_00001slx

1TAW | pdb_00001taw

1TBQ | pdb_00001tbq

1TBR | pdb_00001tbr

1TFX | pdb_00001tfx

1VIT | pdb_00001vit

3TGI | pdb_00003tgi

3TGJ | pdb_00003tgj