4AN3 | pdb_00004an3

Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.

CHAIN

A

Histone acetyltransferase KAT2A - Homo sapiens

Explore Sequence Annotations in 3D

CHAIN A

UNIPROT Q92830

SECONDARY STRUCTURE

UNMODELED

EDS ATOMS

OCC WT AVG B

AVERAGE OCCUPANCY

ATOMIC CLASHES

RSRZ

RSR

RSCC

BURIED RESIDUES

ARTIFACT

HYDROPATHY

DISORDER

DISORDERED BINDING

PFAM

CATH

SCOP

ECOD

MOLECULE PROCESSING

ACTIVE SITE

MODIFIED RESIDUE

MUTAGENESIS

DOMAIN

REGION

LOADING 8%

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.