Download MendeleyComplex structure of kinase domain of DAP kinase with Staurosporine
Ueda, Y., Ogata, H., Yamakawa, A., Higuchi, Y.To be published.
1WVY | pdb_00001wvy
Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors
- PDB DOI: https://doi.org/10.2210/pdb1WVY/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2004-12-27 Released: 2006-04-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.274 (Depositor)
- R-Value Work: 0.213 (Depositor)
- R-Value Observed: 0.222 (Depositor)
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Death-associated protein kinase 1 | 278 | Homo sapiens | Mutation(s): 0 EC: 2.7.1.37 (PDB Primary Data), 2.7.11.1 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P53355 (Homo sapiens) Explore P53355 Go to UniProtKB: P53355 | |||||
PHAROS: P53355 GTEx: ENSG00000196730 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P53355 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| STU Query on STU | B [auth A] | STAUROSPORINE C28 H26 N4 O3 HKSZLNNOFSGOKW-FYTWVXJKSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.274 (Depositor)
- R-Value Work: 0.213 (Depositor)
- R-Value Observed: 0.222 (Depositor)
Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 78.911 | α = 90 |
| b = 113.162 | β = 90 |
| c = 50.658 | γ = 90 |
| Software Name | Purpose |
|---|---|
| CNS | refinement |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| CNS | phasing |
Entry History
Deposition Data
- Released Date: 2006-04-11 Deposition Author(s): Ueda, Y., Ogata, H., Yamakawa, A., Higuchi, Y.
Revision History (Full details and data files)
- Version 1.0: 2006-04-11
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2024-03-13
Changes: Data collection, Database references, Derived calculations
