2L8I | pdb_00002l8i

A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA duplex

PDB DOI: https://doi.org/10.2210/pdb2L8I/pdb
BMRB: 17409
NAKB: 2L8I

Classification: DNA
Mutation(s): No

Deposited: 2011-01-13 Released: 2011-12-28
Deposition Author(s): El-Sagheer, A., Brown, T., Ernsting, N., Dehmel, L., Griesinger, C., Mugge, C.

Experimental Data Snapshot

Method: SOLUTION NMR
Conformers Calculated: 100
Conformers Submitted: 11
Selection Criteria: structures with the lowest energy

wwPDB Validation 3D Report Full Report

This is version 1.1 of the entry. See complete history.

Literature

Structure and Dynamics of Triazole-Linked DNA: Biocompatibility Explained.

Dallmann, A., El-Sagheer, A.H., Dehmel, L., Mugge, C., Griesinger, C., Ernsting, N.P., Brown, T.

(2011) Chemistry 17: 14714-14717

PubMed: 22131102 Search on PubMed
DOI: https://doi.org/10.1002/chem.201102979
Primary Citation of Related Structures:
2L8I

Organizational Affiliation

Department of Chemistry, Humboldt-Universität zu Berlin, 12489 Berlin, Germany. andre.dallmann@tum.de

Macromolecule Content

Total Structure Weight: 7.95 kDa
Atom Count: 529
Modelled Residue Count: 25
Deposited Residue Count: 25
Unique nucleic acid chains: 2

Macromolecules

Find similar nucleic acids by: Sequence | 3D Structure

Entity ID: 1
Molecule	Chains	Length	Organism	Image
DNA (5'-D(GPCPTPGPCPAPAPAPCPGPTPCP*G)-3')	A	13	N/A
Sequence Annotations Expand
Reference Sequence LOADING

Find similar nucleic acids by: Sequence | 3D Structure

Entity ID: 2
Molecule	Chains	Length	Organism	Image
DNA (5'-D(CPGPAPCPG(2L8)PTPGPCPAPGPC)-3')	B	12	N/A
Sequence Annotations Expand
Reference Sequence LOADING

Experimental Data & Validation

Experimental Data

Method: SOLUTION NMR
Conformers Calculated: 100
Conformers Submitted: 11
Selection Criteria: structures with the lowest energy

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2011-12-28

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2011-12-28
Type: Initial release
Version 1.1: 2024-05-01
Changes: Data collection, Database references, Derived calculations

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.