Download MendeleyNMR solution structure and analysis of isolated S3b-S4a motif of repeat IV of the human cardiac sodium channel
Hussein, A.K., Bhuiyan, M.H., Arshava, B., Zhuang, J., Poget, S.F.(2021) bioRxiv
7L83 | pdb_00007l83
NMR solution structure of Nav1.5 DIV S3b-S4a paddle motif in DPC micelle
- PDB DOI: https://doi.org/10.2210/pdb7L83/pdb
- BMRB: 30834
- Classification: MEMBRANE PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Membrane Protein: Yes OPM
- Deposited: 2020-12-30 Released: 2021-06-02
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS), National Science Foundation (NSF, United States)
Experimental Data Snapshot
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 10
- Selection Criteria: structures with the lowest energy
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Sodium channel protein type 5 subunit alpha | 37 | Homo sapiens | Mutation(s): 0 Gene Names: SCN5A Membrane Entity: Yes |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q14524 (Homo sapiens) Explore Q14524 Go to UniProtKB: Q14524 | |||||
PHAROS: Q14524 GTEx: ENSG00000183873 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q14524 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 10
- Selection Criteria: structures with the lowest energy
Entry History & Funding Information
Deposition Data
- Released Date: 2021-06-02 Deposition Author(s): Hussein, A.K., Bhuiyan, M.H., Arshava, B., Zhuang, J., Poget, S.F.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | 1R15GM124606-01 |
| National Science Foundation (NSF, United States) | United States | MCB-1253277 |
Revision History (Full details and data files)
- Version 1.0: 2021-06-02
Type: Initial release - Version 1.1: 2023-06-14
Changes: Database references, Other - Version 1.2: 2024-05-15
Changes: Data collection, Database references
