Download MendeleyMultimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils
Sanchez, J.C., Borcik, C.G., Tonelli, M., Sibert, B., Rienstra, C.M., Wright, E.R.To be published.
9CK3 | pdb_00009ck3
Cryo-EM structure of in-vitro alpha-synuclein fibril
- PDB DOI: https://doi.org/10.2210/pdb9CK3/pdb
- EM Map EMD-45639: EMDB EMDataResource
- Classification: STRUCTURAL PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2024-07-08 Released: 2024-07-24
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS), National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 2.04 Å
- Aggregation State: FILAMENT
- Reconstruction Method: HELICAL
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Alpha-synuclein | 140 | Homo sapiens | Mutation(s): 0 Gene Names: SNCA, NACP, PARK1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P37840 (Homo sapiens) Explore P37840 Go to UniProtKB: P37840 | |||||
PHAROS: P37840 GTEx: ENSG00000145335 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P37840 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 2.04 Å
- Aggregation State: FILAMENT
- Reconstruction Method: HELICAL
| Task | Software Package | Version |
|---|---|---|
| RECONSTRUCTION | RELION | |
| MODEL REFINEMENT | PHENIX |
Entry History & Funding Information
Deposition Data
- Released Date: 2024-07-24 Deposition Author(s): Sanchez, J.C., Borcik, C.G., Tonelli, M., Sibert, B., Rienstra, C.M., Wright, E.R.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | U24GM139168 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | T32GM135066 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | F32GM149118 |
| National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) | United States | RF1NS110436 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | P41GM136463 |
Revision History (Full details and data files)
- Version 1.0: 2024-07-24
Type: Initial release
