1FNT | pdb_00001fnt

CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Class II glutamine amidotransferases	8036842	3000131	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Class II glutamine amidotransferases	8036842	3000131	SCOP2B (2022-06-29)
L	SCOP2 Family	Proteasome subunits	8079503	4002254	SCOP2 (2022-06-29)
L	SCOP2 Superfamily	Class II glutamine amidotransferases	8079504	3000131	SCOP2 (2022-06-29)
Z	SCOP2B Superfamily	Class II glutamine amidotransferases	8079504	3000131	SCOP2B (2022-06-29)
CA [auth c]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
DA [auth d]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
EA [auth e]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
FA [auth f]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
GA [auth g]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
HA [auth h]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
IA [auth i]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
JA [auth j]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
KA [auth k]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
LA [auth l]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
MA [auth m]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
NA [auth n]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
OA [auth o]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
PA [auth p]	SCOP2B Superfamily	Proteasome activator-like	8032475	3001611	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Class II glutamine amidotransferases	8064048	3000131	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Class II glutamine amidotransferases	8064048	3000131	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Class II glutamine amidotransferases	8064020	3000131	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	Class II glutamine amidotransferases	8064020	3000131	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Class II glutamine amidotransferases	8064012	3000131	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Class II glutamine amidotransferases	8064012	3000131	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Class II glutamine amidotransferases	8064026	3000131	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Class II glutamine amidotransferases	8064026	3000131	SCOP2B (2022-06-29)
F	SCOP2 Family	Proteasome subunits	8064065	4002254	SCOP2 (2022-06-29)
F	SCOP2 Superfamily	Class II glutamine amidotransferases	8064066	3000131	SCOP2 (2022-06-29)
T	SCOP2B Superfamily	Class II glutamine amidotransferases	8064066	3000131	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Class II glutamine amidotransferases	8079169	3000131	SCOP2B (2022-06-29)
U	SCOP2B Superfamily	Class II glutamine amidotransferases	8079169	3000131	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Class II glutamine amidotransferases	8036787	3000131	SCOP2B (2022-06-29)
V	SCOP2B Superfamily	Class II glutamine amidotransferases	8036787	3000131	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Proteasome	e1fntA1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
O	Proteasome	e1fntO1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
J	Proteasome	e1fntJ1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
X	Proteasome	e1fntX1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
K	Proteasome	e1fntK1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
Y	Proteasome	e1fntY1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
L	Proteasome	e1fntL1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
Z	Proteasome	e1fntZ1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
AA [auth a]	Proteasome	e1fnta1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
M	Proteasome	e1fntM1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
BA [auth b]	Proteasome	e1fntb1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
N	Proteasome	e1fntN1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
CA [auth c]	PA28_beta_1	e1fntc1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
DA [auth d]	PA28_beta_1	e1fntd1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
EA [auth e]	PA28_beta_1	e1fnte1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
FA [auth f]	PA28_beta_1	e1fntf1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
GA [auth g]	PA28_beta_1	e1fntg1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
HA [auth h]	PA28_beta_1	e1fnth1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
IA [auth i]	PA28_beta_1	e1fnti1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
JA [auth j]	PA28_beta_1	e1fntj1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
KA [auth k]	PA28_beta_1	e1fntk1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
LA [auth l]	PA28_beta_1	e1fntl1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
MA [auth m]	PA28_beta_1	e1fntm1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
NA [auth n]	PA28_beta_1	e1fntn1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
OA [auth o]	PA28_beta_1	e1fnto1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
PA [auth p]	PA28_beta_1	e1fntp1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Proteasome activator reg(alpha) (From Topology)	T: Proteasome activator reg(alpha)	F: PA28_beta_1	ECOD (1.6)
B	Proteasome	e1fntB1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
P	Proteasome	e1fntP1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
C	Proteasome	e1fntC1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
Q	Proteasome	e1fntQ1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
D	Proteasome	e1fntD1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
R	Proteasome	e1fntR1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
E	Proteasome	e1fntE1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
S	Proteasome	e1fntS1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
F	Proteasome	e1fntF1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
T	Proteasome	e1fntT1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
G	Proteasome	e1fntG1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
U	Proteasome	e1fntU1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
H	Proteasome	e1fntH1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
V	Proteasome	e1fntV1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
I	Proteasome	e1fntI1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)
W	Proteasome	e1fntW1	A: a+b four layers	X: Ntn/PP2C	H: Ntn	T: Proteasome subunits	F: Proteasome	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
O	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
J	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
X	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
K	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
Y	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
L	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
Z	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
AA [auth a]	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
M	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
BA [auth b]	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
N	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
CA [auth c]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
DA [auth d]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
EA [auth e]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
FA [auth f]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
GA [auth g]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
HA [auth h]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
IA [auth i]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
JA [auth j]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
KA [auth k]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
LA [auth l]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
MA [auth m]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
NA [auth n]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
OA [auth o]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
PA [auth p]	1.20.120.180	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Proteasome activator pa28, C-terminal domain	CATH (4.3.0)
B	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
P	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
C	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
Q	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
D	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
R	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
E	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
S	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
F	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
T	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
G	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
U	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
H	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
V	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
I	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)
W	3.60.20.10	Alpha Beta	4-Layer Sandwich	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	Aminohydrolase, N-terminal nucleophile (Ntn) domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, O	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
A, O	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
J, X	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
J, X	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
K, Y	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
K, Y	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
L, Z	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
L, Z	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
AA [auth a], M	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
AA [auth a], M	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
BA [auth b], N	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
BA [auth b], N	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
B, P	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
B, P	PF10584	Proteasome subunit A N-terminal signature (Proteasome_A_N)	Proteasome subunit A N-terminal signature	-	Family
B, P	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
C, Q	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
C, Q	PF10584	Proteasome subunit A N-terminal signature (Proteasome_A_N)	Proteasome subunit A N-terminal signature	-	Family
C, Q	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
D, R	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
D, R	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
E, S	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
E, S	PF10584	Proteasome subunit A N-terminal signature (Proteasome_A_N)	Proteasome subunit A N-terminal signature	-	Family
E, S	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
F, T	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
F, T	PF10584	Proteasome subunit A N-terminal signature (Proteasome_A_N)	Proteasome subunit A N-terminal signature	-	Family
F, T	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
G, U	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
G, U	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
H, V	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
H, V	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain
I, W	PF00227	Proteasome subunit (Proteasome)	Proteasome subunit	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity ...	The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes [1]. Recently evidence of two novel groups of bacterial proteasomes was proposed. The first is Anbu, which is sparsely distributed among cyanobacteria and proteobacteria [1]. The second is call beta-proteobacteria proteasome homologue (BPH) [1].	Domain
I, W	PF12465	Proteasome beta subunits C terminal (Pr_beta_C)	Proteasome beta subunits C terminal	-	Family
I, W	PF02252	Proteasome activator PA28, C-terminal (PA28_C)	Proteasome activator PA28, C-terminal	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/b ...	Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3) [1-4].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, O	PROTEASOME COMPONENT C7-ALPHA	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex, alpha-subunit complex proteasome core complex nucleus
J, X	PROTEASOME COMPONENT PUP3	enzyme regulator activity peptidase activity peptidase regulator activity catalytic activity, acting on a protein molecular function activator activity hydrolase activity peptidase activator activity endopeptidase regulator activity endopeptidase activator activity enzyme activator activity molecular function regulator activity catalytic activity endopeptidase activity	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle
K, Y	PROTEASOME COMPONENT C11	enzyme regulator activity peptidase activity peptidase regulator activity catalytic activity, acting on a protein molecular function activator activity hydrolase activity peptidase activator activity endopeptidase regulator activity endopeptidase activator activity enzyme activator activity molecular function regulator activity catalytic activity endopeptidase activity	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle organelle subcompartment membrane endomembrane system endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum organelle membrane endoplasmic reticulum membrane
L, Z	PROTEASOME COMPONENT PRE2	peptidase activity catalytic activity, acting on a protein threonine-type peptidase activity hydrolase activity catalytic activity endopeptidase activity threonine-type endopeptidase activity	cellular component organization cellular component biogenesis proteasome assembly proteasome core complex assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process cellular component organization cellular component biogenesis proteasome assembly proteasome core complex assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure organelle peroxisome microbody cytoplasm protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure organelle peroxisome microbody cytoplasm intracellular membrane-bounded organelle cytosol proteasome core complex proteasome core complex, beta-subunit complex nucleus
AA [auth a], M	PROTEASOME COMPONENT C5	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex proteasome core complex, beta-subunit complex membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle
BA [auth b], N	PROTEASOME COMPONENT PRE4	-	cellular component organization cellular component biogenesis proteasome assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process cellular component organization cellular component biogenesis proteasome assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], HA [auth h], IA [auth i], JA [auth j], KA [auth k], LA [auth l], MA [auth m], NA [auth n], OA [auth o], PA [auth p]	PROTEASOME ACTIVATOR PROTEIN PA26	-	regulation of cellular process catabolic process proteolysis involved in protein catabolic process macromolecule catabolic process regulation of primary metabolic process regulation of proteolysis involved in protein catabolic process regulation of proteolysis proteolysis protein metabolic process regulation of biological process regulation of protein metabolic process biological regulation primary metabolic process proteasomal protein catabolic process regulation of cellular process catabolic process proteolysis involved in protein catabolic process macromolecule catabolic process regulation of primary metabolic process regulation of proteolysis involved in protein catabolic process regulation of proteolysis proteolysis protein metabolic process regulation of biological process regulation of protein metabolic process biological regulation primary metabolic process proteasomal protein catabolic process regulation of macromolecule metabolic process protein catabolic process regulation of catabolic process regulation of proteasomal protein catabolic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process regulation of protein catabolic process	proteasome accessory complex protein-containing complex intracellular anatomical structure cellular anatomical structure catalytic complex peptidase complex proteasome activator complex proteasome complex endopeptidase complex intracellular protein-containing complex
B, P	PROTEASOME COMPONENT Y7	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle cytoplasm proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
C, Q	PROTEASOME COMPONENT Y13	-	cellular component organization cellular component biogenesis proteasome assembly proteasome core complex assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process cellular component organization cellular component biogenesis proteasome assembly proteasome core complex assembly cellular component assembly protein-containing complex organization protein-containing complex assembly cellular process cellular component organization or biogenesis catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex cytoplasm cytosol intracellular organelle organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex cytoplasm cytosol intracellular organelle organelle membraneless organelle intracellular membraneless organelle proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
D, R	PROTEASOME COMPONENT PRE6	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex proteasome core complex, alpha-subunit complex proteasome core complex nuclear outer membrane-endoplasmic reticulum membrane network membrane endomembrane system membraneless organelle intracellular membraneless organelle proteasome storage granule nucleus
E, S	PROTEASOME COMPONENT PUP2	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle cytoplasm proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
F, T	PROTEASOME COMPONENT PRE5	-	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle cytoplasm proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
G, U	PROTEASOME COMPONENT C1	RNA binding binding nucleic acid binding mRNA binding	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex intracellular anatomical structure cellular anatomical structure proteasome core complex, alpha-subunit complex proteasome core complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle cytoplasm proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
H, V	PROTEASOME COMPONENT PRE3	peptidase activity catalytic activity, acting on a protein threonine-type peptidase activity hydrolase activity catalytic activity endopeptidase activity threonine-type endopeptidase activity	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle
I, W	PROTEASOME COMPONENT PUP1	peptidase activity catalytic activity, acting on a protein threonine-type peptidase activity hydrolase activity catalytic activity endopeptidase activity threonine-type endopeptidase activity	catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process proteasomal ubiquitin-independent protein catabolic process macromolecule catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process	protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle protein-containing complex catalytic complex peptidase complex proteasome complex endopeptidase complex intracellular protein-containing complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol proteasome core complex proteasome core complex, beta-subunit complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle proteasome storage granule membrane-bounded organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, O	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
A, O	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
A, O	IPR050115	Proteasome subunit alpha	Family
A, O	IPR023332	Proteasome alpha-type subunit	Family
A, O	IPR001353	Proteasome, subunit alpha/beta	Family
A, O	IPR034642	Proteasome subunit alpha6	Family
J, X	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
J, X	IPR023333	Proteasome B-type subunit	Family
J, X	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
J, X	IPR001353	Proteasome, subunit alpha/beta	Family
J, X	IPR033811	Proteasome beta 3 subunit	Family
K, Y	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
K, Y	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
K, Y	IPR023333	Proteasome B-type subunit	Family
K, Y	IPR001353	Proteasome, subunit alpha/beta	Family
K, Y	IPR035206	Proteasome subunit beta 2	Family
L, Z	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
L, Z	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
L, Z	IPR023333	Proteasome B-type subunit	Family
L, Z	IPR001353	Proteasome, subunit alpha/beta	Family
L, Z	IPR000243	Peptidase T1A, proteasome beta-subunit	Family
AA [auth a], M	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
AA [auth a], M	IPR023333	Proteasome B-type subunit	Family
AA [auth a], M	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
AA [auth a], M	IPR001353	Proteasome, subunit alpha/beta	Family
BA [auth b], N	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
BA [auth b], N	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
BA [auth b], N	IPR023333	Proteasome B-type subunit	Family
BA [auth b], N	IPR016295	Proteasome subunit beta 4	Family
BA [auth b], N	IPR001353	Proteasome, subunit alpha/beta	Family
CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], HA [auth h], IA [auth i], JA [auth j], KA [auth k], LA [auth l], MA [auth m], NA [auth n], OA [auth o], PA [auth p]	IPR003186	Proteasome activator PA28, C-terminal domain	Domain
CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], HA [auth h], IA [auth i], JA [auth j], KA [auth k], LA [auth l], MA [auth m], NA [auth n], OA [auth o], PA [auth p]	IPR036252	Proteasome activator superfamily	Homologous Superfamily
CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], CA [auth c], DA [auth d], EA [auth e], FA [auth f], GA [auth g], HA [auth h], IA [auth i], JA [auth j], KA [auth k], LA [auth l], MA [auth m], NA [auth n], OA [auth o], PA [auth p]	IPR036997	Proteasome activator PA28, C-terminal domain superfamily	Homologous Superfamily
B, P	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
B, P	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
B, P	IPR050115	Proteasome subunit alpha	Family
B, P	IPR023332	Proteasome alpha-type subunit	Family
B, P	IPR001353	Proteasome, subunit alpha/beta	Family
C, Q	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
C, Q	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
C, Q	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
C, Q	IPR050115	Proteasome subunit alpha	Family
C, Q	IPR023332	Proteasome alpha-type subunit	Family
C, Q	IPR001353	Proteasome, subunit alpha/beta	Family
D, R	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
D, R	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
D, R	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
D, R	IPR050115	Proteasome subunit alpha	Family
D, R	IPR023332	Proteasome alpha-type subunit	Family
D, R	IPR001353	Proteasome, subunit alpha/beta	Family
E, S	IPR033812	Proteasome subunit alpha5	Family
E, S	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
E, S	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
E, S	IPR050115	Proteasome subunit alpha	Family
E, S	IPR023332	Proteasome alpha-type subunit	Family
E, S	IPR001353	Proteasome, subunit alpha/beta	Family
F, T	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
F, T	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
F, T	IPR050115	Proteasome subunit alpha	Family
F, T	IPR023332	Proteasome alpha-type subunit	Family
F, T	IPR001353	Proteasome, subunit alpha/beta	Family
G, U	IPR000426	Proteasome alpha-subunit, N-terminal domain	Domain
G, U	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
G, U	IPR050115	Proteasome subunit alpha	Family
G, U	IPR023332	Proteasome alpha-type subunit	Family
G, U	IPR001353	Proteasome, subunit alpha/beta	Family
H, V	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
H, V	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
H, V	IPR023333	Proteasome B-type subunit	Family
H, V	IPR001353	Proteasome, subunit alpha/beta	Family
H, V	IPR000243	Peptidase T1A, proteasome beta-subunit	Family
I, W	IPR016050	Proteasome beta-type subunit, conserved site	Conserved Site
I, W	IPR029055	Nucleophile aminohydrolases, N-terminal	Homologous Superfamily
I, W	IPR024689	Proteasome beta subunit, C-terminal	Domain
I, W	IPR023333	Proteasome B-type subunit	Family
I, W	IPR001353	Proteasome, subunit alpha/beta	Family
I, W	IPR000243	Peptidase T1A, proteasome beta-subunit	Family