1K54
OXA-10 class D beta-lactamase partially acylated with reacted 6beta-(1-hydroxy-1-methylethyl) penicillanic acid
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- AMR Gene: CARD Annotation
- AMR Gene Family: CARD Annotation
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
D | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8037816 | 3001604 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8037816 | 3001604 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8037816 | 3001604 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8037816 | 3001604 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
D | Transpeptidase_1st | e1k54D1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
D | Transpeptidase_2nd_1 | e1k54D2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
C | Transpeptidase_1st | e1k54C1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
C | Transpeptidase_2nd_1 | e1k54C2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
A | Transpeptidase_1st | e1k54A1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
A | Transpeptidase_2nd_1 | e1k54A2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
B | Transpeptidase_1st | e1k54B1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
B | Transpeptidase_2nd_1 | e1k54B2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
D | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
C | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
A | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
B | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
AMR Gene: CARD Annotation CARD Database Homepage
Chains | Accession | Short Name | Description | Provenance Source (Version) |
---|---|---|---|---|
ARO:3001405 | OXA-10 | OXA-10 is a beta-lactamase found in Acinetobacter baumannii and P. aeruginosa. | CARD (3.3.0) | |
ARO:3001405 | OXA-10 | OXA-10 is a beta-lactamase found in Acinetobacter baumannii and P. aeruginosa. | CARD (3.3.0) | |
ARO:3001405 | OXA-10 | OXA-10 is a beta-lactamase found in Acinetobacter baumannii and P. aeruginosa. | CARD (3.3.0) | |
ARO:3001405 | OXA-10 | OXA-10 is a beta-lactamase found in Acinetobacter baumannii and P. aeruginosa. | CARD (3.3.0) |
AMR Gene Family: CARD Annotation CARD Database Homepage
Chains | Accession | Gene Family | Drug Class | Resistance Machanism | Provenance Source (Version) |
---|---|---|---|---|---|
ARO:3007697 | OXA-10-like beta-lactamase | cephalosporin, penam | antibiotic inactivation | CARD (3.3.0) | |
ARO:3007697 | OXA-10-like beta-lactamase | cephalosporin, penam | antibiotic inactivation | CARD (3.3.0) | |
ARO:3007697 | OXA-10-like beta-lactamase | cephalosporin, penam | antibiotic inactivation | CARD (3.3.0) | |
ARO:3007697 | OXA-10-like beta-lactamase | cephalosporin, penam | antibiotic inactivation | CARD (3.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00905 | Penicillin binding protein transpeptidase domain (Transpeptidase) | Penicillin binding protein transpeptidase domain | The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family. | Domain | |
PF00905 | Penicillin binding protein transpeptidase domain (Transpeptidase) | Penicillin binding protein transpeptidase domain | The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR012338 | Beta-lactamase/transpeptidase-like | Homologous Superfamily | |
IPR001460 | Penicillin-binding protein, transpeptidase | Domain | |
IPR050515 | Bacterial Transpeptidases and Beta-Lactamases | Family | |
IPR002137 | Beta-lactamase, class-D active site | Active Site | |
IPR012338 | Beta-lactamase/transpeptidase-like | Homologous Superfamily | |
IPR001460 | Penicillin-binding protein, transpeptidase | Domain | |
IPR050515 | Bacterial Transpeptidases and Beta-Lactamases | Family | |
IPR002137 | Beta-lactamase, class-D active site | Active Site |