Annotations: 2CZO

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PX	e2czoA1	A: a+b two layers	X: PX domain (From Topology)	H: PX domain (From Topology)	T: PX domain	F: PX	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1520.10	Alpha Beta	2-Layer Sandwich	PX Domain	Phox-like domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00787	PX domain (PX)	PX domain	PX domains bind to phosphoinositides.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Bud emergence protein 1	protein-macromolecule adaptor activity molecular adaptor activity binding phospholipid binding lipid binding phosphatidylinositol-3-phosphate binding phosphatidylinositol phosphate binding phosphatidylinositol binding	developmental process anatomical structure morphogenesis sexual reproduction reproductive process anatomical structure development cell morphogenesis involved in conjugation with cellular fusion cell morphogenesis conjugation with cellular fusion cytoskeleton-dependent cytokinesis mitotic cytokinesis cytokinesis establishment or maintenance of cell polarity mitotic cell cycle establishment of cell polarity developmental process anatomical structure morphogenesis sexual reproduction reproductive process anatomical structure development cell morphogenesis involved in conjugation with cellular fusion cell morphogenesis conjugation with cellular fusion cytoskeleton-dependent cytokinesis mitotic cytokinesis cytokinesis establishment or maintenance of cell polarity mitotic cell cycle establishment of cell polarity mitotic cell cycle process cellular process cell cycle cell division cellular bud site selection cell cycle process cellular response to stimulus regulation of biological process regulation of signaling regulation of cellular process small GTPase-mediated signal transduction response to stimulus signaling regulation of small GTPase mediated signal transduction biological regulation regulation of signal transduction regulation of Rho protein signal transduction intracellular signal transduction Rho protein signal transduction cell communication regulation of intracellular signal transduction regulation of response to stimulus intracellular signaling cassette regulation of cell communication signal transduction positive regulation of organelle organization regulation of cellular component organization positive regulation of cellular component organization vacuole organization positive regulation of vacuole organization positive regulation of vacuole fusion, non-autophagic positive regulation of biological process regulation of vacuole organization regulation of organelle organization cellular component organization organelle fusion organelle organization vacuole fusion vacuole fusion, non-autophagic regulation of vacuole fusion, non-autophagic cellular component organization or biogenesis positive regulation of cellular process maintenance of protein location protein localization localization cellular localization cellular macromolecule localization macromolecule localization maintenance of location	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle incipient cellular bud site site of polarized growth cellular bud cellular bud tip cell periphery cell cortex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle incipient cellular bud site site of polarized growth cellular bud cellular bud tip cell periphery cell cortex cell projection mating projection cell tip mating projection tip cell pole plasma membrane bounded cell projection protein kinase complex transferase complex, transferring phosphorus-containing groups PAR polarity complex protein-containing complex catalytic complex serine/threonine protein kinase complex transferase complex cytoskeleton membraneless organelle intracellular membraneless organelle cellular bud neck

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR051228	NADPH Oxidase and PX Domain-Containing	Family
A	IPR001683	Phox homology	Domain
A	IPR000270	PB1 domain	Domain
A	IPR036028	SH3-like domain superfamily	Homologous Superfamily
A	IPR035550	Bem1/Scd2, PX domain	Domain
A	IPR035549	Bem1/Scd2, SH3 domain 2	Domain
A	IPR035548	Bem1/Scd2, SH3 domain 1	Domain
A	IPR053793	PB1-like domain	Domain
A	IPR036871	PX domain superfamily	Homologous Superfamily
A	IPR001452	SH3 domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.