Annotations: 2F6H

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth X]	d2f6hx_	All alpha proteins	alpha-alpha superhelix	DIL domain-like	DIL domains from class V myosins	Myosin-2 (Myo2p) cargo binding domain	baker's yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth X]	DIL	e2f6hX1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: DIL	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth X]	PF01843	DIL domain (DIL)	DIL domain	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth X]	Myosin-2	small GTPase binding protein binding binding enzyme binding GTPase binding cytoskeletal protein binding actin binding protein-containing complex binding actin filament binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding small GTPase binding protein binding binding enzyme binding GTPase binding cytoskeletal protein binding actin binding protein-containing complex binding actin filament binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding calmodulin binding polypeptide conformation or assembly isomerase activity isomerase activity cytoskeletal motor activity microfilament motor activity macromolecular conformation isomerase activity catalytic activity ATP-dependent activity	cellular component organization mitochondrion distribution localization mitochondrion localization organelle organization organelle localization organelle inheritance mitochondrion inheritance cellular process cellular component organization or biogenesis intracellular distribution of mitochondria protein localization establishment of protein localization cellular localization cellular component organization mitochondrion distribution localization mitochondrion localization organelle organization organelle localization organelle inheritance mitochondrion inheritance cellular process cellular component organization or biogenesis intracellular distribution of mitochondria protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of localization protein transport cellular macromolecule localization macromolecule localization secretion export from cell membrane docking vesicle-mediated transport organelle localization by membrane tethering secretion by cell exocytosis vesicle docking exocytic process vesicle docking involved in exocytosis vacuole organization vacuole inheritance membrane organization cytokinetic process cell cycle cytokinesis cell division membrane addition at site of cytokinesis cell cycle process establishment of organelle localization microtubule cytoskeleton organization spindle localization establishment or maintenance of cell polarity mitotic cell cycle establishment of mitotic spindle localization establishment of spindle localization establishment of spindle orientation establishment of localization in cell microtubule cytoskeleton organization involved in mitosis establishment of cell polarity mitotic cell cycle process establishment of mitotic spindle orientation microtubule-based process cytoskeleton organization Golgi inheritance Golgi organization endomembrane system organization peroxisome organization peroxisome inheritance vesicle transport along actin filament vesicle cytoskeletal trafficking vesicle localization establishment of vesicle localization intracellular transport actin filament-based movement actin filament-based process cytoskeleton-dependent intracellular transport actin filament-based transport actin cytoskeleton organization actin filament organization supramolecular fiber organization	cellular anatomical structure incipient cellular bud site site of polarized growth membrane cellular bud cellular bud tip membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton membraneless organelle intracellular membraneless organelle cellular anatomical structure incipient cellular bud site site of polarized growth membrane cellular bud cellular bud tip membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton membraneless organelle intracellular membraneless organelle actin cytoskeleton cell projection mating projection cell tip mating projection tip cell pole plasma membrane bounded cell projection transport vesicle intracellular vesicle intracellular membrane-bounded organelle endomembrane system cytoplasmic vesicle cytoplasm protein-containing complex myosin complex myosin V complex unconventional myosin complex actin filament bundle vacuolar membrane storage vacuole lytic vacuole vacuole fungal-type vacuole lytic vacuole membrane bounding membrane of organelle organelle membrane fungal-type vacuole membrane nucleus membrane protein complex nuclear protein-containing complex nuclear membrane protein complex organelle envelope microtubule organizing center attachment site nuclear membrane microtubule tethering complex nuclear envelope meiotic nuclear membrane microtubule tethering complex polymeric cytoskeletal fiber actin filament filamentous actin supramolecular fiber supramolecular polymer supramolecular complex Myo2p-Vac17p-Vac8p transport complex cellular bud neck

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth X]	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
A [auth X]	IPR001609	Myosin head, motor domain-like	Domain
A [auth X]	IPR002710	Dilute domain	Domain
A [auth X]	IPR000048	IQ motif, EF-hand binding site	Binding Site
A [auth X]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
A [auth X]	IPR036103	Class V myosin, motor domain	Domain
A [auth X]	IPR046943	Myosin 2/2A, cargo-binding domain, fungi	Domain
A [auth X]	IPR004009	Myosin, N-terminal, SH3-like	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.