Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2nr6a1 All beta proteins Acid proteases Acid proteases automated matches automated matches German cockroach (Blattella germanica ) [TaxId: 6973 ], SCOPe (2.08)
Ad2nr6a2 Artifacts Tags Tags Tags N-terminal Tags German cockroach (Blattella germanica ) [TaxId: 6973 ], SCOPe (2.08)
Bd2nr6b1 All beta proteins Acid proteases Acid proteases automated matches automated matches German cockroach (Blattella germanica ) [TaxId: 6973 ], SCOPe (2.08)
Bd2nr6b2 Artifacts Tags Tags Tags N-terminal Tags German cockroach (Blattella germanica ) [TaxId: 6973 ], SCOPe (2.08)
Cd2nr6c2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Cd2nr6c1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Ed2nr6e2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Ed2nr6e1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Dd2nr6d_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Fd2nr6f_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyAcid proteases 8066387 3001059 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyAcid proteases 8066387 3001059 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAsp_Ce2nr6A3 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_CECOD (1.6)
AAsp_Ne2nr6A2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_NECOD (1.6)
BAsp_Ce2nr6B3 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_CECOD (1.6)
BAsp_Ne2nr6B2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_NECOD (1.6)
CC1-set_4e2nr6C2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
CV-sete2nr6C1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
EC1-set_4e2nr6E2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
EV-sete2nr6E1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
DV-set_8e2nr6D2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
DC1-set_1e2nr6D1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
FV-set_8e2nr6F2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
FC1-set_1e2nr6F1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.40.1960 Mainly Beta Sandwich Immunoglobulin-like CATH (4.3.0)
A2.40.70.10 Mainly Beta Beta Barrel Cathepsin D, subunit A domain 1CATH (4.3.0)
B2.60.40.1960 Mainly Beta Sandwich Immunoglobulin-like CATH (4.3.0)
B2.40.70.10 Mainly Beta Beta Barrel Cathepsin D, subunit A domain 1CATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
E2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
F2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
C, E
FAB-GAMMA-1_KAPPA L-KAPPA Mus musculus (house mouse) IGKV6-17*01, IGKJ1*01, IGKJ2*01, IGKC*01, IGKC*02 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-1_KAPPA IMGT (202449-0)
D, F
FAB-GAMMA-1_KAPPA VH-CH1 Mus musculus (house mouse) IGHV14-3*02, IGHJ4*01, IGHG1*02 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_KAPPA IMGT (202449-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
C, E
Light ChainIGKV6 Kappaaspartic protease bla g 2SAbDab (2024-12-13)
D, F
Heavy ChainIGHV14 -aspartic protease bla g 2SAbDab (2024-12-13)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00026Eukaryotic aspartyl protease (Asp)Eukaryotic aspartyl protease- Family

InterPro: Protein Family Classification InterPro Database Homepage

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, B
CSX Parent Component: CYS

RESIDAA0451

PSI-MOD :  2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide MOD:01380