3DPY
Protein farnesyltransferase complexed with FPP and caged TKCVIM substrate
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d3dpya1 | All alpha proteins | alpha-alpha superhelix | Protein prenylyltransferase | Protein prenylyltransferase | Protein farnesyltransferase alpha-subunit | brown rat,rat,rats (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
B | d3dpyb1 | All alpha proteins | alpha/alpha toroid | Terpenoid cyclases/Protein prenyltransferases | Protein prenyltransferases | Protein farnesyltransferase, beta-subunit | brown rat,rat,rats (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PPTA | e3dpyA1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PPTA | ECOD (1.6) |
B | SQHop_cyclase_C | e3dpyB1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: alpha/alpha toroid (From Topology) | T: alpha/alpha toroid | F: SQHop_cyclase_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.25.40.120 | Mainly Alpha | Alpha Horseshoe | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat | Protein prenylyltransferase | CATH (4.3.0) |
B | 1.50.10.20 | Mainly Alpha | Alpha/alpha barrel | Glycosyltransferase | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01239 | Protein prenyltransferase alpha subunit repeat (PPTA) | Protein prenyltransferase alpha subunit repeat | - | Repeat | |
PF00432 | Prenyltransferase alpha-alpha toroid domain (Prenyltrans) | Prenyltransferase and squalene oxidase repeat | - | Repeat | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR002088 | Protein prenyltransferase, alpha subunit | Repeat | |
IPR026872 | Protein farnesyltransferase subunit beta | Family | |
IPR045089 | Prenyltransferase subunit beta | Family | |
IPR008930 | Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid | Homologous Superfamily | |
IPR001330 | Prenyltransferase alpha-alpha toroid domain | Domain |