3IY6 | pdb_00003iy6

Variable domains of the computer generated model (WAM) of Fab E fitted into the cryoEM reconstruction of the virus-Fab E complex

External Resource: Annotation

Domain Annotation: ECOD Classification
IMGT Antibody Annotation
SAbDab Antibody Annotation
Thera-SAbDab Antibody Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	V-set	e3iy6A1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
B	V-set_8	e3iy6B1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)

IMGT Antibody Annotation IMGT Database Homepage

Chain	Protein Name	Description	Organism Name	Gene Allele Name(s)	Domain Name(s)	Receptor Type	Receptor Description	Provenance Source
A	Antibody Fv fragment from neutralizing antibody E	V-KAPPA	Rattus norvegicus (Norway rat)	IGKV6S1001, IGKJ501	V-DOMAIN V-KAPPA	IG	FV-HEAVY_KAPPA	IMGT (202510-0)
B	Antibody Fv fragment from neutralizing antibody E	VH	Rattus norvegicus (Norway rat)	IGHV2-3201, IGHJ301	V-DOMAIN VH	IG	FV-HEAVY_KAPPA	IMGT (202510-0)

SAbDab Antibody Annotation SAbDab Database Homepage

Chain	Chain Class	Chain Subclass	Chain Type	Antigen Name(s)	Provenance Source
A	Light Chain	IGKV6	Kappa	-	SAbDab (2025-03-21)
B	Heavy Chain	IGHV2	-	-	SAbDab (2025-03-21)

Thera-SAbDab Antibody Annotation Thera-SAbDab Database Homepage

Chain	Name	Target	Provenance Source
A	Anivovetmab	Minor Capsid VP2 (Canine)	Therapeutic SAbDab (2025-03-21)
B	Anivovetmab	Minor Capsid VP2 (Canine)	Therapeutic SAbDab (2025-03-21)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.