Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyYjgF-like 8035953 3001733 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ACM_1e3zo8A1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)
BCM_1e3zo8B1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)
CCM_1e3zo8C1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)
ECM_1e3zo8E1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)
FCM_1e3zo8F1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)
DCM_1e3zo8D1 A: a+b three layersX: Bacillus chorismate mutase-likeH: YjgF-like (From Topology)T: YjgF-likeF: CM_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
B3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
C3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
E3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
F3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
D3.30.1330.40 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF07736Chorismate mutase type I (CM_1)Chorismate mutase type IChorismate mutase (CM) EC:5.4.99.5 catalyses the the conversion of chorismate to prephenate in the shikimate pathway of tyrosine and phenylalanine biosynthesis in bacteria, fungi and plants [1,2]. The three types of CM are AroH class, AroQ class, ...Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR008243Chorismate mutase, AroH classFamily
A, B, C, D, E
IPR035959RutC-like superfamilyHomologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

ChainsEnzyme NameDescriptionCatalytic Residues
D, F
chorismate mutase (AroH)  M-CSA #474

Chorismate mutase (CM; EC:5.4.99.5) catalyses the rearrangement of chorismate to prephenat, the reaction at the branch point of the biosynthetic pathway leading to the three aromatic amino acids, phenylalanine, tryptophan and tyrosine (chorismic acid is the last common intermediate, and CM leads to the L-phenylalanine/L-tyrosine branch). It is part of the shikimate pathway, which is present only in bacteria, fungi and plants.

This entry represents a family of monofunctional (non-fused) chorismate mutases from Gram-positive bacteria (Firmicutes) and cyanobacteria. They are monofunctional, homotrimeric, non-allosteric enzymes and are not regulated by the end-product aromatic amino acids (unlike those CMs of the AroQ-type).

Defined by 7 residues: ARG:D-7GLU:D-78ARG:D-90TYR:D-108ARG:D-116ARG:F-63CYS:F-75
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