4K10
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4k10a_ | All alpha proteins | Terpenoid synthases | Terpenoid synthases | automated matches | automated matches | (Leishmania major ) [TaxId: 5664 ], | SCOPe (2.08) |
C [auth D] | d4k10d_ | All alpha proteins | Terpenoid synthases | Terpenoid synthases | automated matches | automated matches | (Leishmania major ) [TaxId: 5664 ], | SCOPe (2.08) |
B | d4k10b_ | All alpha proteins | Terpenoid synthases | Terpenoid synthases | automated matches | automated matches | (Leishmania major ) [TaxId: 5664 ], | SCOPe (2.08) |
D [auth C] | d4k10c_ | All alpha proteins | Terpenoid synthases | Terpenoid synthases | automated matches | automated matches | (Leishmania major ) [TaxId: 5664 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Terpenoid synthases | 8073832 | 3001615 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | Terpenoid synthases | 8073832 | 3001615 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Terpenoid synthases | 8073832 | 3001615 | SCOP2B (2022-06-29) |
D [auth C] | SCOP2B Superfamily | Terpenoid synthases | 8073832 | 3001615 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | polyprenyl_synt | e4k10A1 | A: alpha bundles | X: Terpenoid synthases (From Topology) | H: Terpenoid synthases (From Topology) | T: Terpenoid synthases | F: polyprenyl_synt | ECOD (1.6) |
C [auth D] | polyprenyl_synt | e4k10D1 | A: alpha bundles | X: Terpenoid synthases (From Topology) | H: Terpenoid synthases (From Topology) | T: Terpenoid synthases | F: polyprenyl_synt | ECOD (1.6) |
B | polyprenyl_synt | e4k10B1 | A: alpha bundles | X: Terpenoid synthases (From Topology) | H: Terpenoid synthases (From Topology) | T: Terpenoid synthases | F: polyprenyl_synt | ECOD (1.6) |
D [auth C] | polyprenyl_synt | e4k10C1 | A: alpha bundles | X: Terpenoid synthases (From Topology) | H: Terpenoid synthases (From Topology) | T: Terpenoid synthases | F: polyprenyl_synt | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.600.10 | Mainly Alpha | Orthogonal Bundle | Farnesyl Diphosphate Synthase | Farnesyl Diphosphate Synthase | CATH (4.3.0) |
C [auth D] | 1.10.600.10 | Mainly Alpha | Orthogonal Bundle | Farnesyl Diphosphate Synthase | Farnesyl Diphosphate Synthase | CATH (4.3.0) |
B | 1.10.600.10 | Mainly Alpha | Orthogonal Bundle | Farnesyl Diphosphate Synthase | Farnesyl Diphosphate Synthase | CATH (4.3.0) |
D [auth C] | 1.10.600.10 | Mainly Alpha | Orthogonal Bundle | Farnesyl Diphosphate Synthase | Farnesyl Diphosphate Synthase | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B, C [auth D], D [auth C] | PF00348 | Polyprenyl synthetase (polyprenyl_synt) | Polyprenyl synthetase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B, C [auth D], D [auth C] | IPR039702 | Farnesyl pyrophosphate synthase-like | Family |
A, B, C [auth D], D [auth C] | IPR008949 | Isoprenoid synthase domain superfamily | Homologous Superfamily |
A, B, C [auth D], D [auth C] | IPR033749 | Polyprenyl synthetase, conserved site | Conserved Site |
A, B, C [auth D], D [auth C] | IPR000092 | Polyprenyl synthetase-like | Family |