5GJ9

Crystal structure of Arabidopsis thaliana ACO2 in complex with POA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d5gj9b_	All beta proteins	Double-stranded beta-helix	Clavaminate synthase-like	Penicillin synthase-like	automated matches	Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
A	d5gj9a_	All beta proteins	Double-stranded beta-helix	Clavaminate synthase-like	Penicillin synthase-like	automated matches	Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Clavaminate synthase-like	8072517	3001848	SCOP2B (2022-06-29)
A	SCOP2 Family	Penicillin synthase-like	8072516	4002884	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Clavaminate synthase-like	8072517	3001848	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	DIOX_N	e5gj9B1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: DIOX_N	ECOD (1.6)
A	DIOX_N	e5gj9A1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: DIOX_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.60.120.330	Mainly Beta	Sandwich	Jelly Rolls	B-lactam Antibiotic, Isopenicillin N Synthase	CATH (4.3.0)
A	2.60.120.330	Mainly Beta	Sandwich	Jelly Rolls	B-lactam Antibiotic, Isopenicillin N Synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03171	2OG-Fe(II) oxygenase superfamily (2OG-FeII_Oxy)	2OG-Fe(II) oxygenase superfamily	This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily [1]. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reacti ...	This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily [1]. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site [3]. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB.	Domain
A, B	PF14226	non-haem dioxygenase in morphine synthesis N-terminal (DIOX_N)	non-haem dioxygenase in morphine synthesis N-terminal	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	1-aminocyclopropane-1-carboxylate oxidase 2	oxidoreductase activity monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1-aminocyclopropane-1-carboxylate oxidase activity catalytic activity cation binding transition metal ion binding copper ion binding ion binding binding metal ion binding small molecule binding organic acid binding oxidoreductase activity monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1-aminocyclopropane-1-carboxylate oxidase activity catalytic activity cation binding transition metal ion binding copper ion binding ion binding binding metal ion binding small molecule binding organic acid binding carbohydrate binding vitamin binding organic cyclic compound binding anion binding monosaccharide binding carboxylic acid binding heterocyclic compound binding L-ascorbic acid binding	developmental process multicellular organismal process regulation of biological process regulation of multicellular organismal development regulation of developmental process positive regulation of seed germination biological regulation positive regulation of biological process regulation of seedling development seed germination seedling development positive regulation of developmental process multicellular organism development regulation of post-embryonic development regulation of seed germination developmental process multicellular organismal process regulation of biological process regulation of multicellular organismal development regulation of developmental process positive regulation of seed germination biological regulation positive regulation of biological process regulation of seedling development seed germination seedling development positive regulation of developmental process multicellular organism development regulation of post-embryonic development regulation of seed germination anatomical structure development positive regulation of multicellular organismal process positive regulation of post-embryonic development regulation of multicellular organismal process post-embryonic development cellular response to stimulus response to lipid response to stimulus response to fatty acid response to oxygen-containing compound cellular response to oxygen-containing compound cellular response to fatty acid cellular response to chemical stimulus response to chemical cellular response to lipid cellular process alkene metabolic process olefinic compound biosynthetic process ethylene metabolic process hydrocarbon metabolic process olefin biosynthetic process biosynthetic process alkene biosynthetic process ethylene biosynthetic process olefinic compound metabolic process metabolic process olefin metabolic process hydrocarbon biosynthetic process cellular response to nitrogen compound response to nitrogen compound cellular response to nitric oxide response to nitric oxide cellular response to reactive nitrogen species defense response response to stress detection of stimulus response to hormone response to endogenous stimulus detection of hormone stimulus detection of chemical stimulus response to ethylene detection of ethylene stimulus	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure Golgi apparatus organelle cytoplasm intracellular membrane-bounded organelle endomembrane system cytosol cell periphery plasma membrane membrane cell-cell junction membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure Golgi apparatus organelle cytoplasm intracellular membrane-bounded organelle endomembrane system cytosol cell periphery plasma membrane membrane cell-cell junction symplast anchoring junction cell junction plasmodesma external encapsulating structure plant-type cell wall cell wall nucleus endoplasmic reticulum

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR050295	Plant 2-oxoglutarate-dependent oxidoreductases	Family
A, B	IPR005123	Oxoglutarate/iron-dependent dioxygenase domain	Domain
A, B	IPR027443	Isopenicillin N synthase-like superfamily	Homologous Superfamily
A, B	IPR044861	Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain	Domain
A, B	IPR026992	Non-haem dioxygenase N-terminal domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.