6NHB
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d6nhbb_ | Alpha and beta proteins (a+b) | Nitric oxide (NO) synthase oxygenase domain | Nitric oxide (NO) synthase oxygenase domain | Nitric oxide (NO) synthase oxygenase domain | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A | d6nhba_ | Alpha and beta proteins (a+b) | Nitric oxide (NO) synthase oxygenase domain | Nitric oxide (NO) synthase oxygenase domain | Nitric oxide (NO) synthase oxygenase domain | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | NO_synthase | e6nhbB1 | A: a+b complex topology | X: Nitric oxide (NO) synthase oxygenase domain (From Topology) | H: Nitric oxide (NO) synthase oxygenase domain (From Topology) | T: Nitric oxide (NO) synthase oxygenase domain | F: NO_synthase | ECOD (1.6) |
A | NO_synthase | e6nhbA1 | A: a+b complex topology | X: Nitric oxide (NO) synthase oxygenase domain (From Topology) | H: Nitric oxide (NO) synthase oxygenase domain (From Topology) | T: Nitric oxide (NO) synthase oxygenase domain | F: NO_synthase | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.90.340.10 | Alpha Beta | Alpha-Beta Complex | Nitric Oxide Synthase | Chain A, domain 1 | CATH (4.3.0) |
B | 3.90.440.10 | Alpha Beta | Alpha-Beta Complex | Nitric Oxide Synthase | Heme Domain | CATH (4.3.0) |
B | 3.90.1230.10 | Alpha Beta | Alpha-Beta Complex | Bovine Endothelial Nitric Oxide Synthase Heme Domain | Chain: A,domain 3 | CATH (4.3.0) |
A | 3.90.340.10 | Alpha Beta | Alpha-Beta Complex | Nitric Oxide Synthase | Chain A, domain 1 | CATH (4.3.0) |
A | 3.90.440.10 | Alpha Beta | Alpha-Beta Complex | Nitric Oxide Synthase | Heme Domain | CATH (4.3.0) |
A | 3.90.1230.10 | Alpha Beta | Alpha-Beta Complex | Bovine Endothelial Nitric Oxide Synthase Heme Domain | Chain: A,domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02898 | Nitric oxide synthase, oxygenase domain (NO_synthase) | Nitric oxide synthase, oxygenase domain | - | Domain |