6SH1
Crystal structure of substrate-free human neprilysin E584D.
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B [auth CCC] | SCOP2B Superfamily | Metalloproteases (zincins), catalytic domain | 8035463 | 3001975 | SCOP2B (2022-06-29) |
A [auth AAA] | SCOP2B Superfamily | Metalloproteases (zincins), catalytic domain | 8035463 | 3001975 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth CCC] | Peptidase_M13 | e6sh1CCC1 | A: mixed a+b and a/b | X: Zincin-like | H: Metalloproteases (zincins) catalytic domain (From Topology) | T: Metalloproteases (zincins) catalytic domain | F: Peptidase_M13 | ECOD (1.6) |
A [auth AAA] | Peptidase_M13 | e6sh1AAA1 | A: mixed a+b and a/b | X: Zincin-like | H: Metalloproteases (zincins) catalytic domain (From Topology) | T: Metalloproteases (zincins) catalytic domain | F: Peptidase_M13 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth AAA], B [auth CCC] | PF05649 | Peptidase family M13 (Peptidase_M13_N) | Peptidase family M13 | - | Family |
A [auth AAA], B [auth CCC] | PF01431 | Peptidase family M13 (Peptidase_M13) | Peptidase family M13 | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A [auth AAA], B [auth CCC] | IPR018497 | Peptidase M13, C-terminal domain | Domain |
A [auth AAA], B [auth CCC] | IPR008753 | Peptidase M13, N-terminal domain | Domain |
A [auth AAA], B [auth CCC] | IPR000718 | Peptidase M13 | Family |
A [auth AAA], B [auth CCC] | IPR024079 | Metallopeptidase, catalytic domain superfamily | Homologous Superfamily |
A [auth AAA], B [auth CCC] | IPR042089 | Peptidase M13, domain 2 | Homologous Superfamily |