7AKC

Structure of the of AcylTransferase domain of phenolphthiocerol/phtiocerol synthase A from Mycobacterium bovis (BCG)

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Acyl_transf_1_1st	e7akcA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: FabD/lysophospholipase-like	F: Acyl_transf_1_1st	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00698	Acyl transferase domain (Acyl_transf_1)	Acyl transferase domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Phenolpthiocerol synthesis type-I polyketide synthase ppsA	vitamin binding amide binding modified amino acid binding binding phosphopantetheine binding small molecule binding acyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity fatty acid synthase activity	cellular component biogenesis cellular component organization peptidoglycan-based cell wall biogenesis cellular component assembly cell wall biogenesis DIM/DIP cell wall layer assembly cell wall organization or biogenesis cellular process Actinobacterium-type cell wall biogenesis cellular component organization or biogenesis fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process cellular component biogenesis cellular component organization peptidoglycan-based cell wall biogenesis cellular component assembly cell wall biogenesis DIM/DIP cell wall layer assembly cell wall organization or biogenesis cellular process Actinobacterium-type cell wall biogenesis cellular component organization or biogenesis fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process biosynthetic process small molecule metabolic process metabolic process monocarboxylic acid metabolic process lipid metabolic process	cell periphery cellular anatomical structure plasma membrane membrane intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR016035	Acyl transferase/acyl hydrolase/lysophospholipase	Homologous Superfamily
A	IPR014031	Beta-ketoacyl synthase, C-terminal	Domain
A	IPR006162	Phosphopantetheine attachment site	PTM
A	IPR020807	Polyketide synthase, dehydratase domain	Domain
A	IPR049552	Polyketide synthase, dehydratase domain, N-terminal	Domain
A	IPR013968	Polyketide synthase, ketoreductase domain	Domain
A	IPR016036	Malonyl-CoA ACP transacylase, ACP-binding	Homologous Superfamily
A	IPR050091	Polyketide and Nonribosomal Peptide Biosynthesis Enzymes	Family
A	IPR020841	Polyketide synthase, beta-ketoacyl synthase domain	Domain
A	IPR036736	ACP-like superfamily	Homologous Superfamily
A	IPR014043	Acyl transferase domain	Domain
A	IPR032821	Polyketide synthase, C-terminal extension	Domain
A	IPR009081	Phosphopantetheine binding ACP domain	Domain
A	IPR020806	Polyketide synthase-like, phosphopantetheine-binding domain	Domain
A	IPR016039	Thiolase-like	Homologous Superfamily
A	IPR001227	Acyl transferase domain superfamily	Homologous Superfamily
A	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
A	IPR018201	Beta-ketoacyl synthase, active site	Active Site
A	IPR014030	Beta-ketoacyl synthase-like, N-terminal	Domain
A	IPR042104	Polyketide synthase, dehydratase domain superfamily	Homologous Superfamily
A	IPR049900	Polyketide/metazoan fatty acid synthase, dehydratase domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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7AKC

Structure of the of AcylTransferase domain of phenolphthiocerol/phtiocerol synthase A from Mycobacterium bovis (BCG)

External Resource: Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage