7O9M | pdb_00007o9m

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
J [auth K]SCOP2B SuperfamilyRibosomal protein L13 8100460 3001134 SCOP2B (2022-06-29)
K [auth L]SCOP2B Superfamily50S Ribosomal protein L14-like 8072072 3000433 SCOP2B (2022-06-29)
N [auth O]SCOP2B SuperfamilyProkaryotic ribosomal protein L17 8033689 3000995 SCOP2B (2022-06-29)
BA [auth 1]SCOP2B SuperfamilyZn-binding ribosomal proteins 8075050 3001320 SCOP2B (2022-06-29)
EA [auth 4]SCOP2B SuperfamilyRibosomal protein L36 8083324 3001346 SCOP2B (2022-06-29)
JA [auth 9]SCOP2B SuperfamilyMitochondrial ribosomal protein L27-like 8053893 3002240 SCOP2B (2022-06-29)
BB [auth n]SCOP2B SuperfamilyS-adenosyl-L-methionine-dependent methyltransferases 8076347 3000118 SCOP2B (2022-06-29)
FB [auth u]SCOP2B SuperfamilyNucleotidyltransferase-like 8100396 3000129 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyRibosomal protein L4 8080706 3001146 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
J [auth K]Ribosomal_L13e7o9mK1 A: a/b three-layered sandwichesX: Ribosomal protein L13/L15p/L18e/L32eH: Ribosomal protein L13 and L16-A (From Topology)T: Ribosomal protein L13 and L16-AF: Ribosomal_L13ECOD (1.6)
K [auth L]Ribosomal_L14e7o9mL1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: Ribosomal_L14ECOD (1.6)
L [auth M]Ribosomal_L27Ae7o9mM1 A: a/b three-layered sandwichesX: Ribosomal protein L13/L15p/L18e/L32eH: Ribosomal proteins L15p and L18e (From Topology)T: Ribosomal proteins L15p and L18eF: Ribosomal_L27AECOD (1.6)
M [auth N]Ribosomal_L16e7o9mN1 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: Ribosomal protein L10eF: Ribosomal_L16ECOD (1.6)
N [auth O]Ribosomal_L17e7o9mO1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Prokaryotic ribosomal protein L17 (From Topology)T: Prokaryotic ribosomal protein L17F: Ribosomal_L17ECOD (1.6)
O [auth P]Ribosomal_L18pe7o9mP1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Ribosomal_L18pECOD (1.6)
P [auth Q]Ribosomal_L19e7o9mQ1 A: beta barrelsX: SH3H: SH3T: SH3F: Ribosomal_L19ECOD (1.6)
Q [auth R]Ribosomal_L20e7o9mR1 A: alpha arraysX: PABP domain-likeH: Ribosomal protein L20 (From Topology)T: Ribosomal protein L20F: Ribosomal_L20ECOD (1.6)
R [auth S]Ribosomal_L21pe7o9mS1 A: beta barrelsX: Ribosomal protein L21p (From Topology)H: Ribosomal protein L21p (From Topology)T: Ribosomal protein L21pF: Ribosomal_L21pECOD (1.6)
S [auth T]Ribosomal_L22e7o9mT1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Ribosomal protein L22 (From Topology)T: Ribosomal protein L22F: Ribosomal_L22ECOD (1.6)
T [auth U]Ribosomal_L23_2e7o9mU1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: Ribosomal_L23_2ECOD (1.6)
U [auth V]ribosomal_L24_1e7o9mV1 A: beta barrelsX: SH3H: SH3T: SH3F: ribosomal_L24_1ECOD (1.6)
V [auth W]Ribosomal_L27e7o9mW1 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: Ribosomal L27 proteinF: Ribosomal_L27ECOD (1.6)
W [auth X]Ribosomal_L28_1e7o9mX1 A: few secondary structure elementsX: Ribosomal protein bL28-related (From Homology)H: Ribosomal protein bL28-relatedT: Ribosomal protein L28F: Ribosomal_L28_1ECOD (1.6)
X [auth Y]MRP-L47e7o9mY1 A: alpha bundlesX: Long alpha-hairpinH: Ribosomal protein L29 (L29p) (From Topology)T: Ribosomal protein L29 (L29p)F: MRP-L47ECOD (1.6)
Y [auth Z]Ribosomal_L30e7o9mZ1 A: a+b two layersX: Ribosomal protein L30p/L7e (From Topology)H: Ribosomal protein L30p/L7e (From Topology)T: Ribosomal protein L30p/L7eF: Ribosomal_L30ECOD (1.6)
Z [auth a]MRP-S32e7o9ma1 A: extended segmentsX: Mitoribosomal protein mL42 (From Topology)H: Mitoribosomal protein mL42 (From Topology)T: Mitoribosomal protein mL42F: MRP-S32ECOD (1.6)
AA [auth 0]KOG4080e7o9m01 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG4080ECOD (1.6)
BA [auth 1]Ribosomal_L33e7o9m11 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: Ribosomal_L33ECOD (1.6)
CA [auth 2]Ribosomal_L34e7o9m21 A: extended segmentsX: 50S ribosomal protein L34 (From Topology)H: 50S ribosomal protein L34 (From Topology)T: 50S ribosomal protein L34F: Ribosomal_L34ECOD (1.6)
CMnmE_helical_2nde7o9mC1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: MnmE_helical_2ndECOD (1.6)
DA [auth 3]Ribosomal_L35pe7o9m31 A: a+b two layersX: Ribosomal protein L35p (From Topology)H: Ribosomal protein L35p (From Topology)T: Ribosomal protein L35pF: Ribosomal_L35pECOD (1.6)
EA [auth 4]Ribosomal_L36e7o9m41 A: few secondary structure elementsX: Ribosomal protein L36 (From Topology)H: Ribosomal protein L36 (From Topology)T: Ribosomal protein L36F: Ribosomal_L36ECOD (1.6)
FA [auth 5]PDCD9e7o9m51 A: a/b three-layered sandwichesX: Restriction endonuclease-likeH: Restriction endonuclease-like (From Topology)T: Restriction endonuclease-likeF: PDCD9ECOD (1.6)
GA [auth 6]PBPe7o9m61 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: PEBP-likeF: PBPECOD (1.6)
HA [auth 7]TGSe7o9m71 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: TGSECOD (1.6)
HA [auth 7]tRNA_SADe7o9m72 A: a+b two layersX: LuxS, MPP, ThrRS/AlaRS common domainH: LuxS, MPP, ThrRS/AlaRS common domainT: ThrRS/AlaRS editing domainF: tRNA_SADECOD (1.6)
IA [auth 8]MRP-L28e7o9m81 A: extended segmentsX: Mitochondrial 54S ribosomal protein L28 (From Topology)H: Mitochondrial 54S ribosomal protein L28 (From Topology)T: Mitochondrial 54S ribosomal protein L28F: MRP-L28ECOD (1.6)
JA [auth 9]MRP-L27e7o9m91 A: extended segmentsX: Mitochondrial 54S ribosomal protein L27 (From Topology)H: Mitochondrial 54S ribosomal protein L27 (From Topology)T: Mitochondrial 54S ribosomal protein L27F: MRP-L27ECOD (1.6)
KA [auth b]L51_S25_CI-B8e7o9mb1 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: L51_S25_CI-B8ECOD (1.6)
LA [auth c]Ribonucleas_3_3e7o9mc1 A: alpha arraysX: RNase III catalytic domain-like (From Topology)H: RNase III catalytic domain-like (From Topology)T: RNase III catalytic domain-likeF: Ribonucleas_3_3ECOD (1.6)
LA [auth c]dsrme7o9mc2 A: a+b two layersX: dsRBD-likeH: dsRNA-binding domain-like (From Topology)T: dsRNA-binding domain-likeF: dsrmECOD (1.6)
MA [auth d]Tim44e7o9md1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: Tim44ECOD (1.6)
DRibosomal_L2e7o9mD2 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_L2ECOD (1.6)
DRibosomal_L2_Ce7o9mD1 A: beta barrelsX: SH3H: SH3T: SH3F: Ribosomal_L2_CECOD (1.6)
NA [auth e]MRP-L46e7o9me1 A: a+b two layersX: beta-GraspH: Nudix (From Topology)T: NudixF: MRP-L46ECOD (1.6)
OA [auth f]Ribosomal_S10_2e7o9mf1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal protein S10 (From Topology)T: Ribosomal protein S10F: Ribosomal_S10_2ECOD (1.6)
PA [auth g]Img2e7o9mg1 A: a+b two layersX: Glucose permease domain IIB-likeH: eIF1-like (From Topology)T: eIF1-likeF: Img2ECOD (1.6)
QA [auth h]Ribosomal_L50e7o9mh1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: Ribosomal_L50ECOD (1.6)
RA [auth i]MRP-L51e7o9mi1 A: alpha bundlesX: Long alpha-hairpinH: Mitoribosomal protein mL51 (From Topology)T: Mitoribosomal protein mL51F: MRP-L51ECOD (1.6)
SA [auth j]EUF08791e7o9mj1 A: extended segmentsX: Mitoribosomal protein mL52 (From Topology)H: Mitoribosomal protein mL52 (From Topology)T: Mitoribosomal protein mL52F: EUF08791ECOD (1.6)
TA [auth k]MRP_L53e7o9mk1 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: MRP_L53ECOD (1.6)
VA [auth m]Mitoc_L55e7o9mm1 A: few secondary structure elementsX: Ribosomal protein L31p (From Topology)H: Ribosomal protein L31p (From Topology)T: Ribosomal protein L31pF: Mitoc_L55ECOD (1.6)
WA [auth o]MRP-63e7o9mo1 A: extended segmentsX: Mitoribosomal protein mL63 (From Topology)H: Mitoribosomal protein mL63 (From Topology)T: Mitoribosomal protein mL63F: MRP-63ECOD (1.6)
ERibosomal_L3e7o9mE1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: Ribosomal_L3ECOD (1.6)
XA [auth p]RF-1_Ne7o9mp1 A: a+b two layersX: dsRBD-likeH: Peptidyl-tRNA hydrolase domain-like (From Topology)T: Peptidyl-tRNA hydrolase domain-likeF: RF-1_NECOD (1.6)
YA [auth q]CR6_interacte7o9mq1 A: extended segmentsX: Mitochondrial 54S ribosomal protein L25 (From Topology)H: Mitochondrial 54S ribosomal protein L25 (From Topology)T: Mitochondrial 54S ribosomal protein L25F: CR6_interactECOD (1.6)
ZA [auth r]Ribosomal_S18e7o9mr1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: Ribosomal_S18ECOD (1.6)
AB [auth s]PDCD9e7o9ms1 A: a/b three-layered sandwichesX: Restriction endonuclease-likeH: Restriction endonuclease-like (From Topology)T: Restriction endonuclease-likeF: PDCD9ECOD (1.6)
BB [auth n]FtsJe7o9mn1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: FtsJECOD (1.6)
CB [auth A1]Methyltr_RsmB-F_1e7o9mA11 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: Methyltr_RsmB-F_1ECOD (1.6)
DB [auth A2]mTERFe7o9mA21 A: alpha superhelicesX: Mitochondrial mTERF-likeH: Mitochondrial mTERF (From Topology)T: Mitochondrial mTERFF: mTERFECOD (1.6)
EB [auth v]Complex1_LYRe7o9mv1 A: alpha bundlesX: LYR protein (From Topology)H: LYR protein (From Topology)T: LYR proteinF: Complex1_LYRECOD (1.6)
FB [auth u]RsfSe7o9mu1 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: RsfSECOD (1.6)
KB [auth t6]Ribosomal_L12_N_1e7o9mt61 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
GB [auth t1]Ribosomal_L12_N_1e7o9mt11 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
HB [auth t2]Ribosomal_L12_N_1e7o9mt21 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
IB [auth t3]Ribosomal_L12_N_1e7o9mt31 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
JB [auth t4]Ribosomal_L12_N_1e7o9mt41 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
LB [auth t5]Ribosomal_L12_N_1e7o9mt51 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
FRibosomal_L4e7o9mF1 A: a/b three-layered sandwichesX: Ribosomal protein L4 (From Topology)H: Ribosomal protein L4 (From Topology)T: Ribosomal protein L4F: Ribosomal_L4ECOD (1.6)
MB [auth w]PP-bindinge7o9mw1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)
G [auth H]Ribosomal_L9_N_1e7o9mH1 A: a+b two layersX: L9 N-domain-likeH: L9 N-domain-like (From Topology)T: L9 N-domain-likeF: Ribosomal_L9_N_1ECOD (1.6)
I [auth J]Ribosomal_L11e7o9mJ2 A: alpha arraysX: HTHH: HTHT: Ribosomal protein L11, C-terminal domainF: Ribosomal_L11ECOD (1.6)
I [auth J]Ribosomal_L11_Ne7o9mJ1 A: a+b two layersX: Ribosomal protein L11/L12e N-terminal domain-likeH: Ribosomal protein L11/L12e N-terminal domain (From Topology)T: Ribosomal protein L11/L12e N-terminal domainF: Ribosomal_L11_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
J [auth K]PF1078039S ribosomal protein L53/MRP-L53 (MRP_L53)39S ribosomal protein L53/MRP-L53- Family
J [auth K]PF00572Ribosomal protein L13 (Ribosomal_L13)Ribosomal protein L13- Family
K [auth L]PF00238Ribosomal protein L14p/L23e (Ribosomal_L14)Ribosomal protein L14p/L23eDomain
L [auth M]PF00828Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27AThis family includes higher eukaryotic ribosomal 60S L27A, archaeal 50S L18e, prokaryotic 50S L15, fungal mitochondrial L10, plant L27A, mitochondrial L15 and chloroplast L18-3 proteins. Domain
M [auth N]PF01728FtsJ-like methyltransferase (FtsJ)FtsJ-like methyltransferase- Family
M [auth N]PF00252Ribosomal protein L16p/L10e (Ribosomal_L16)Ribosomal protein L16p/L10eDomain
N [auth O]PF01196Ribosomal protein L17 (Ribosomal_L17)Ribosomal protein L17- Family
O [auth P]PF00861Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast (Ribosomal_L18p)Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast- Family
P [auth Q]PF01245Ribosomal protein L19 (Ribosomal_L19)Ribosomal protein L19- Family
Q [auth R]PF01084Ribosomal protein S18 (Ribosomal_S18)Ribosomal protein S18- Family
Q [auth R]PF00453Ribosomal protein L20 (Ribosomal_L20)Ribosomal protein L20- Family
R [auth S]PF00829Ribosomal prokaryotic L21 protein (Ribosomal_L21p)Ribosomal prokaryotic L21 protein- Family
S [auth T]PF00237Ribosomal protein L22p/L17e (Ribosomal_L22)Ribosomal protein L22p/L17eThis family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes. Domain
T [auth U]PF02410Ribosomal silencing factor during starvation (RsfS)Ribosomal silencing factor during starvation- Family
T [auth U]PF00276Ribosomal protein L23 (Ribosomal_L23)Ribosomal protein L23- Family
U [auth V]PF05347Complex 1 protein (LYR family) (Complex1_LYR)Complex 1 protein (LYR family)- Family
U [auth V]PF17136Ribosomal proteins 50S L24/mitochondrial 39S L24 (ribosomal_L24)Ribosomal proteins 50S L24/mitochondrial 39S L24- Family
U [auth V]PF00467KOW motif (KOW)KOW motif- Family
V [auth W]PF00550Phosphopantetheine attachment site (PP-binding)Phosphopantetheine attachment siteA 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes memb ...Domain
W [auth X]PF00830Ribosomal L28 family (Ribosomal_L28)Ribosomal L28 family- Family
X [auth Y]PF06984Mitochondrial 39-S ribosomal protein L47 (MRP-L47) (MRP-L47)Mitochondrial 39-S ribosomal protein L47 (MRP-L47)- Family
Y [auth Z]PF00327Ribosomal protein L30p/L7e (Ribosomal_L30)Ribosomal protein L30p/L7eThis family includes prokaryotic L30 and eukaryotic L7. Domain
AA [auth 0]PF01783Ribosomal L32p protein family (Ribosomal_L32p)Ribosomal L32p protein family- Family
CA [auth 2]PF00468Ribosomal protein L34 (Ribosomal_L34)Ribosomal protein L34- Family
PF22892MRPL44 dsRNA-binding domain (DSRM_MRPL44)MRPL44 dsRNA-binding domainThis double stranded RNA-binding domain is found in the Large ribosomal subunit protein mL44 protein. Domain
PF0192650S ribosome-binding GTPase (MMR_HSR1)50S ribosome-binding GTPase- Family
PF22935Large ribosomal subunit protein mL44, endonuclease domain (RM44_endonuclase)Large ribosomal subunit protein mL44, endonuclease domainLarge ribosomal subunit protein mL44 (RM44) is a component of the 39S subunit of mitochondrial ribosome. It may play a role in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. This entry represents the endonuclease ( ...Domain
DA [auth 3]PF01632Ribosomal protein L35 (Ribosomal_L35p)Ribosomal protein L35- Family
EA [auth 4]PF00444Ribosomal protein L36 (Ribosomal_L36)Ribosomal protein L36Domain
FA [auth 5]PF07147Mitochondrial 28S ribosomal protein S30 (PDCD9) (PDCD9)Mitochondrial 28S ribosomal protein S30 (PDCD9)- Family
GA [auth 6]PF01161Phosphatidylethanolamine-binding protein (PBP)Phosphatidylethanolamine-binding proteinDomain
PF03947Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)Ribosomal Proteins L2, C-terminal domainDomain
PF04280Tim44-like domain (Tim44)Tim44-like domainTim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane [1]. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostati ...Domain
PF00181Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)Ribosomal Proteins L2, RNA binding domainDomain
PF00297Ribosomal protein L3 (Ribosomal_L3)Ribosomal protein L3- Family
PF1178839S mitochondrial ribosomal protein L46 (MRP-L46)39S mitochondrial ribosomal protein L46- Family
CB [auth A1]PF0118916S rRNA methyltransferase RsmB/F (Methyltr_RsmB-F)16S rRNA methyltransferase RsmB/F- Family
PF00338Ribosomal protein S10p/S20e (Ribosomal_S10)Ribosomal protein S10p/S20eThis family includes small ribosomal subunit S10 from prokaryotes and S20 from eukaryotes. Domain
PF00573Ribosomal protein L4/L1 family (Ribosomal_L4)Ribosomal protein L4/L1 family- Family
G [auth H]PF01281Ribosomal protein L9, N-terminal domain (Ribosomal_L9_N)Ribosomal protein L9, N-terminal domainDomain
G [auth H]PF10501Ribosomal subunit 39S (Ribosomal_L50)Ribosomal subunit 39SThe 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units [1]. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components [2]. In E. coli, in the absenc ...Domain
H [auth I]PF10244Mitochondrial ribosomal subunit (MRP-L51)Mitochondrial ribosomal subunit- Family
H [auth I]PF00466Ribosomal protein L10 (Ribosomal_L10)Ribosomal protein L10- Family
I [auth J]PF03946Ribosomal protein L11, N-terminal domain (Ribosomal_L11_N)Ribosomal protein L11, N-terminal domainThe N-terminal domain of Ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain. Domain
I [auth J]PF00298Ribosomal protein L11, RNA binding domain (Ribosomal_L11)Ribosomal protein L11, RNA binding domainDomain
I [auth J]PF18699Mitoribosomal protein mL52 (MRPL52)Mitoribosomal protein mL52- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
16S rRNA---
J [auth K]39S ribosomal protein L13, mitochondrial
K [auth L]39S ribosomal protein L14, mitochondrial
L [auth M]39S ribosomal protein L15, mitochondrial
M [auth N]39S ribosomal protein L16, mitochondrial
N [auth O]39S ribosomal protein L17, mitochondrial
O [auth P]Mitochondrial ribosomal protein L18, isoform CRA_b
P [auth Q]39S ribosomal protein L19, mitochondrial
Q [auth R]39S ribosomal protein L20, mitochondrial
R [auth S]39S ribosomal protein L21, mitochondrial
S [auth T]39S ribosomal protein L22, mitochondrial
MT-TRNAVAL---
T [auth U]39S ribosomal protein L23, mitochondrial
U [auth V]39S ribosomal protein L24, mitochondrial
V [auth W]39S ribosomal protein L27, mitochondrial
W [auth X]39S ribosomal protein L28, mitochondrial
X [auth Y]39S ribosomal protein L47, mitochondrial
Y [auth Z]39S ribosomal protein L30, mitochondrial
Z [auth a]39S ribosomal protein L42, mitochondrial
AA [auth 0]39S ribosomal protein L32, mitochondrial
BA [auth 1]39S ribosomal protein L33, mitochondrial
CA [auth 2]39S ribosomal protein L34, mitochondrial
Mitochondrial ribosome-associated GTPase 1
DA [auth 3]39S ribosomal protein L35, mitochondrial
EA [auth 4]39S ribosomal protein L36, mitochondrial
FA [auth 5]39S ribosomal protein L37, mitochondrial
GA [auth 6]39S ribosomal protein L38, mitochondrial-
HA [auth 7]39S ribosomal protein L39, mitochondrial
IA [auth 8]39S ribosomal protein L40, mitochondrial
JA [auth 9]39S ribosomal protein L41, mitochondrial
KA [auth b]39S ribosomal protein L43, mitochondrial
LA [auth c]39S ribosomal protein L44, mitochondrial
MA [auth d]39S ribosomal protein L45, mitochondrial
39S ribosomal protein L2, mitochondrial
NA [auth e]39S ribosomal protein L46, mitochondrial
OA [auth f]39S ribosomal protein L48, mitochondrial-
PA [auth g]39S ribosomal protein L49, mitochondrial
QA [auth h]39S ribosomal protein L50, mitochondrial-
RA [auth i]39S ribosomal protein L51, mitochondrial
SA [auth j]39S ribosomal protein L52, mitochondrial
TA [auth k]39S ribosomal protein L53, mitochondrial-
UA [auth l]39S ribosomal protein L54, mitochondrial
VA [auth m]39S ribosomal protein L55, mitochondrial
WA [auth o]Ribosomal protein 63, mitochondrial
39S ribosomal protein L3, mitochondrial
XA [auth p]Peptidyl-tRNA hydrolase ICT1, mitochondrial
YA [auth q]Growth arrest and DNA damage-inducible proteins-interacting protein 1-
ZA [auth r]39S ribosomal protein S18a, mitochondrial
AB [auth s]39S ribosomal protein S30, mitochondrial
BB [auth n]rRNA methyltransferase 2, mitochondrial
CB [auth A1]5-methylcytosine rRNA methyltransferase NSUN4
DB [auth A2]Transcription termination factor 4, mitochondrial
EB [auth v]MIEF1 upstream open reading frame protein
FB [auth u]Mitochondrial assembly of ribosomal large subunit protein 1
39S ribosomal protein L12, mitochondrial
39S ribosomal protein L4, mitochondrial
MB [auth w]Acyl carrier protein, mitochondrial
NB [auth UNK]Unknown residues---
G [auth H]39S ribosomal protein L9, mitochondrial
H [auth I]39S ribosomal protein L10, mitochondrial
I [auth J]39S ribosomal protein L11, mitochondrial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
J [auth K]IPR023563Large ribosomal subunit protein uL13, conserved siteConserved Site
J [auth K]IPR005822Large ribosomal subunit protein uL13Family
J [auth K]IPR036899Large ribosomal subunit protein uL13 superfamilyHomologous Superfamily
J [auth K]IPR005823Large ribosomal subunit protein uL13, bacterial-typeFamily
K [auth L]IPR036853Large ribosomal subunit protein uL14 superfamilyHomologous Superfamily
K [auth L]IPR000218Large ribosomal subunit protein uL14Family
L [auth M]IPR005749Large ribosomal subunit protein uL15, bacterial-typeFamily
L [auth M]IPR021131Large ribosomal subunit protein uL15/eL18Domain
L [auth M]IPR030878Large ribosomal subunit protein uL15Family
L [auth M]IPR036227Large ribosomal subunit protein uL15/eL18 superfamilyHomologous Superfamily
M [auth N]IPR036920Large ribosomal subunit protein uL16 superfamilyHomologous Superfamily
M [auth N]IPR000114Large ribosomal subunit protein uL16, bacterial-typeFamily
M [auth N]IPR016180Large ribosomal subunit protein uL16 domainDomain
M [auth N]IPR047873Large ribosomal subunit protein uL16Family
N [auth O]IPR036373Large ribosomal subunit protein bL17 superfamilyHomologous Superfamily
N [auth O]IPR000456Large ribosomal subunit protein bL17Family
O [auth P]IPR005484Large ribosomal subunit protein uL18Family
O [auth P]IPR036967Small ribosomal subunit protein uS11 superfamilyHomologous Superfamily
P [auth Q]IPR001857Large ribosomal subunit protein bL19Family
P [auth Q]IPR038657Large ribosomal subunit protein bL19 superfamilyHomologous Superfamily
P [auth Q]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
Q [auth R]IPR035566Ribosomal protein bL20, C-terminalHomologous Superfamily
Q [auth R]IPR005813Large ribosomal subunit protein bL20Family
R [auth S]IPR028909Large ribosomal subunit protein bL21-likeFamily
R [auth S]IPR001787Large ribosomal subunit protein bL21Family
R [auth S]IPR036164Large ribosomal subunit protein bL21-like superfamilyHomologous Superfamily
S [auth T]IPR047867Large ribosomal subunit protein uL22, bacterial/organelle-typeFamily
S [auth T]IPR036394Ribosomal protein uL22 superfamilyHomologous Superfamily
S [auth T]IPR001063Large ribosomal subunit protein uL22Family
T [auth U]IPR012678Ribosomal protein uL23/eL15/eS24 core domain superfamilyHomologous Superfamily
T [auth U]IPR012677Nucleotide-binding alpha-beta plait domain superfamilyHomologous Superfamily
T [auth U]IPR013025Large ribosomal subunit protein uL23-likeFamily
U [auth V]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
U [auth V]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
U [auth V]IPR003256Large ribosomal subunit protein uL24Family
U [auth V]IPR041988Large ribosomal subunit protein uL24, KOW domainDomain
U [auth V]IPR005824KOWDomain
U [auth V]IPR005825Large ribosomal subunit protein uL24, conserved siteConserved Site
V [auth W]IPR001684Large ribosomal subunit protein bL27Family
W [auth X]IPR037147Large ribosomal subunit protein bL28 superfamilyHomologous Superfamily
W [auth X]IPR026569Large ribosomal subunit protein bL28Family
W [auth X]IPR034704Large ribosomal subunit protein bL28/bL31-like superfamilyHomologous Superfamily
X [auth Y]IPR038340MRP-L47 superfamily, mitochondrialHomologous Superfamily
X [auth Y]IPR010729Large ribosomal subunit protein uL29m, mitochondrialFamily
Y [auth Z]IPR036919Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamilyHomologous Superfamily
Y [auth Z]IPR005996Large ribosomal subunit protein uL30, bacterial-typeFamily
Y [auth Z]IPR016082Large ribosomal subunit protein uL30-like, ferredoxin-like fold domainDomain
Z [auth a]IPR019346Large ribosomal subunit protein mL42Family
AA [auth 0]IPR002677Large ribosomal subunit protein bL32Family
AA [auth 0]IPR051991Mitochondrial ribosomal protein bL32Family
AA [auth 0]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
BA [auth 1]IPR052008Mitochondrial ribosomal protein bL33Family
BA [auth 1]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
BA [auth 1]IPR038584Large ribosomal subunit protein bL33 superfamilyHomologous Superfamily
BA [auth 1]IPR001705Large ribosomal subunit protein bL33Family
CA [auth 2]IPR000271Large ribosomal subunit protein bL34Family
IPR030378Circularly permuted (CP)-type guanine nucleotide-binding (G) domainDomain
IPR019991GTP-binding protein, ribosome biogenesisFamily
IPR016478GTPase, MTG1Family
IPR006073GTP binding domainDomain
IPR023179GTP-binding protein, orthogonal bundle domain superfamilyHomologous Superfamily
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
DA [auth 3]IPR021137Large ribosomal subunit protein bL35-likeFamily
DA [auth 3]IPR019338Large ribosomal subunit protein bL35mFamily
DA [auth 3]IPR037229Large ribosomal subunit protein bL35 superfamilyHomologous Superfamily
EA [auth 4]IPR000473Large ribosomal subunit protein bL36Family
EA [auth 4]IPR052143Mitochondrial Large Ribosomal Subunit bL36mFamily
EA [auth 4]IPR035977Large ribosomal subunit protein bL36 superfamilyHomologous Superfamily
FA [auth 5]IPR052482Mitochondrial large ribosomal subunit mL37Family
FA [auth 5]IPR010793Large ribosomal subunit protein mL37/mL65Family
GA [auth 6]IPR036610PEBP-like superfamilyHomologous Superfamily
GA [auth 6]IPR008914Phosphatidylethanolamine-binding proteinFamily
GA [auth 6]IPR035810Phosphatidylethanolamine-binding protein, eukaryoticFamily
HA [auth 7]IPR012676TGS-likeHomologous Superfamily
HA [auth 7]IPR018163Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamilyHomologous Superfamily
HA [auth 7]IPR050062Proline-tRNA synthetaseFamily
HA [auth 7]IPR004095TGSDomain
HA [auth 7]IPR012675Beta-grasp domain superfamilyHomologous Superfamily
IA [auth 8]IPR019192Large ribosomal subunit protein mL40Family
IA [auth 8]IPR039145Large ribosomal subunit protein mL40, metazoa/plantsFamily
JA [auth 9]IPR019189Large ribosomal subunit protein mL41Family
KA [auth b]IPR007741Ribosomal protein/NADH dehydrogenase domainDomain
KA [auth b]IPR036249Thioredoxin-like superfamilyHomologous Superfamily
KA [auth b]IPR039927Large ribosomal subunit protein mL43Family
LA [auth c]IPR036389Ribonuclease III, endonuclease domain superfamilyHomologous Superfamily
LA [auth c]IPR044444Large ribosomal subunit protein mL44, dsRNA binding domain, metazoaDomain
LA [auth c]IPR055189Large ribosomal subunit protein mL44, endonuclease domainDomain
LA [auth c]IPR014720Double-stranded RNA-binding domainDomain
MA [auth d]IPR032710NTF2-like domain superfamilyHomologous Superfamily
MA [auth d]IPR007379Tim44-like domainDomain
MA [auth d]IPR051975Mitochondrial Large Ribosomal Subunit mL45Family
IPR022669Large ribosomal subunit protein uL2, C-terminalDomain
IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
IPR022666Large ribosomal subunit protein uL2, RNA-binding domainDomain
IPR002171Large ribosomal subunit protein uL2Family
NA [auth e]IPR015797NUDIX hydrolase-like domain superfamilyHomologous Superfamily
NA [auth e]IPR021757Large ribosomal subunit protein mL46, N-terminalDomain
NA [auth e]IPR040008Large ribosomal subunit protein mL46Family
NA [auth e]IPR033650Large ribosomal subunit protein mL46, NUDIX domainDomain
OA [auth f]IPR027486Small ribosomal subunit protein uS10 domainDomain
OA [auth f]IPR027487Large ribosomal subunit protein mL48Family
OA [auth f]IPR036838Small ribosomal subunit protein uS10 domain superfamilyHomologous Superfamily
PA [auth g]IPR007740Large ribosomal subunit protein mL49Family
QA [auth h]IPR018305Large ribosomal subunit protein mL50Family
RA [auth i]IPR019373Large ribosomal subunit protein mL51Family
SA [auth j]IPR034596Large ribosomal subunit protein mL52Family
TA [auth k]IPR019716Large ribosomal subunit protein mL53Family
TA [auth k]IPR052473Mitochondrial Large Ribosomal Subunit mL53Family
UA [auth l]IPR013870Large ribosomal subunit protein mL54Family
VA [auth m]IPR044884Large ribosomal subunit protein mL55 superfamilyHomologous Superfamily
VA [auth m]IPR018615Large ribosomal subunit protein mL55Family
WA [auth o]IPR016576Large ribosomal subunit protein mL63Family
IPR019926Large ribosomal subunit protein uL3, conserved siteConserved Site
IPR019927Large ribosomal subunit protein uL3, bacterial/organelle-typeFamily
IPR009000Translation protein, beta-barrel domain superfamilyHomologous Superfamily
IPR000597Large ribosomal subunit protein uL3Family
XA [auth p]IPR052104Mitochondrial Release Factor mL62Family
XA [auth p]IPR000352Peptide chain release factor class IDomain
YA [auth q]IPR018472Large ribosomal subunit protein mL64Family
YA [auth q]IPR043035Large ribosomal subunit protein mL64 domain superfamilyHomologous Superfamily
ZA [auth r]IPR001648Small ribosomal subunit protein bS18Family
ZA [auth r]IPR036870Small ribosomal subunit protein bS18 superfamilyHomologous Superfamily
AB [auth s]IPR039982Large ribosomal subunit protein mL65Family
AB [auth s]IPR010793Large ribosomal subunit protein mL37/mL65Family
BB [auth n]IPR029063S-adenosyl-L-methionine-dependent methyltransferase superfamilyHomologous Superfamily
BB [auth n]IPR002877Ribosomal RNA methyltransferase, FtsJ domainDomain
BB [auth n]IPR015507Ribosomal RNA large subunit methyltransferase EFamily
BB [auth n]IPR050082Ribosomal RNA large subunit methyltransferase RlmEFamily
CB [auth A1]IPR001678SAM-dependent methyltransferase RsmB-F/NOP2-type domainDomain
CB [auth A1]IPR029063S-adenosyl-L-methionine-dependent methyltransferase superfamilyHomologous Superfamily
CB [auth A1]IPR023267RNA (C5-cytosine) methyltransferaseFamily
CB [auth A1]IPR049560SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic coreDomain
DB [auth A2]IPR038538MTERF superfamily, mitochondrial/chloroplasticHomologous Superfamily
DB [auth A2]IPR003690Transcription termination factor, mitochondrial/chloroplasticFamily
EB [auth v]IPR008011Complex 1 LYR protein domainDomain
EB [auth v]IPR045300MIEF1-MP, LYR domainDomain
FB [auth u]IPR043519Nucleotidyltransferase superfamilyHomologous Superfamily
FB [auth u]IPR004394Protein Iojap/ribosomal silencing factor RsfSFamily
IPR013823Large ribosomal subunit protein bL12, C-terminalDomain
IPR008932Large ribosomal subunit protein bL12, oligomerizationDomain
IPR036235Large ribosomal subunit protein bL12, oligomerization domain superfamilyHomologous Superfamily
IPR014719Ribosomal protein bL12, C-terminal/adaptor protein ClpS-likeHomologous Superfamily
IPR000206Large ribosomal subunit protein bL12Family
IPR013005Large ribosomal subunit protein uL4-likeFamily
IPR002136Large ribosomal subunit protein uL4Family
IPR023574Large ribosomal subunit protein uL4 domain superfamilyHomologous Superfamily
MB [auth w]IPR006162Phosphopantetheine attachment sitePTM
MB [auth w]IPR036736ACP-like superfamilyHomologous Superfamily
MB [auth w]IPR009081Phosphopantetheine binding ACP domainDomain
MB [auth w]IPR003231Acyl carrier proteinFamily
G [auth H]IPR036935Large ribosomal subunit protein bL9, N-terminal domain superfamilyHomologous Superfamily
G [auth H]IPR020070Large ribosomal subunit protein bL9, N-terminalDomain
G [auth H]IPR054302Large ribosomal subunit protein bL9m, C-terminal domainDomain
G [auth H]IPR009027Large ribosomal subunit protein bL9/RNase H1, N-terminalHomologous Superfamily
G [auth H]IPR000244Large ribosomal subunit protein bL9Family
H [auth I]IPR043141Large ribosomal subunit protein uL10-like domain superfamilyHomologous Superfamily
H [auth I]IPR001790Large ribosomal subunit protein uL10Family
H [auth I]IPR047865Large ribosomal subunit protein uL10, bacterial typeFamily
I [auth J]IPR020783Large ribosomal subunit protein uL11, C-terminalDomain
I [auth J]IPR000911Ribosomal protein uL11Family
I [auth J]IPR006519Large ribosomal subunit protein uL11, bacterial-typeFamily
I [auth J]IPR020784Large ribosomal subunit protein uL11, N-terminalDomain
I [auth J]IPR036769Large ribosomal subunit protein uL11, C-terminal domain superfamilyHomologous Superfamily
I [auth J]IPR036796Large ribosomal subunit protein uL11, N-terminal domain superfamilyHomologous Superfamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
J [auth K]PharosQ9BYD1
K [auth L]PharosQ6P1L8
L [auth M]PharosQ9P015
M [auth N]PharosQ9NX20
N [auth O]PharosQ9NRX2
P [auth Q]PharosP49406
Q [auth R]PharosQ9BYC9
T [auth U]PharosQ16540
U [auth V]PharosQ96A35
V [auth W]PharosQ9P0M9
W [auth X]PharosQ13084
X [auth Y]PharosQ9HD33
Y [auth Z]PharosQ8TCC3
Z [auth a]PharosQ9Y6G3
AA [auth 0]PharosQ9BYC8
BA [auth 1]PharosO75394
CA [auth 2]PharosQ9BQ48
PharosQ9BT17
DA [auth 3]PharosQ9NZE8
EA [auth 4]PharosQ9P0J6
FA [auth 5]PharosQ9BZE1
HA [auth 7]PharosQ9NYK5
IA [auth 8]PharosQ9NQ50
JA [auth 9]PharosQ8IXM3
KA [auth b]PharosQ8N983
LA [auth c]PharosQ9H9J2
MA [auth d]PharosQ9BRJ2
PharosQ5T653
OA [auth f]PharosQ96GC5
PA [auth g]PharosQ13405
QA [auth h]PharosQ8N5N7
RA [auth i]PharosQ4U2R6
SA [auth j]PharosQ86TS9
UA [auth l]PharosQ6P161
VA [auth m]PharosQ7Z7F7
WA [auth o]PharosQ9BQC6
PharosP09001
XA [auth p]PharosQ14197
YA [auth q]PharosQ8TAE8
ZA [auth r]PharosQ9NVS2
AB [auth s]PharosQ9NP92
BB [auth n]PharosQ9UI43
CB [auth A1]PharosQ96CB9
DB [auth A2]PharosQ7Z6M4
EB [auth v]PharosL0R8F8
FB [auth u]PharosQ96EH3
PharosP52815
PharosQ9BYD3
MB [auth w]PharosO14561
G [auth H]PharosQ9BYD2
H [auth I]PharosQ7Z7H8
I [auth J]PharosQ9Y3B7