8ENY

Crystal structure of alpha-COPI-WD40 domain R13A mutant.

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	WD40 repeat-like	8100404	3001694	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	WD40 repeat-like	8100404	3001694	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	WD40 repeat-like	8100404	3001694	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00400	WD domain, G-beta repeat (WD40)	WD domain, G-beta repeat	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Putative coatomer subunit alpha	structural molecule activity cargo receptor activity	localization transport cellular process establishment of localization Golgi vesicle transport vesicle-mediated transport intra-Golgi vesicle-mediated transport protein localization cellular localization establishment of protein localization nitrogen compound transport intracellular transport protein transport establishment of localization in cell localization transport cellular process establishment of localization Golgi vesicle transport vesicle-mediated transport intra-Golgi vesicle-mediated transport protein localization cellular localization establishment of protein localization nitrogen compound transport intracellular transport protein transport establishment of localization in cell cellular macromolecule localization macromolecule localization intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum endoplasmic reticulum to Golgi vesicle-mediated transport	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure Golgi apparatus organelle cytoplasm intracellular membrane-bounded organelle endomembrane system protein-containing complex vesicle coat intracellular vesicle membrane protein complex COPI-coated vesicle membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure Golgi apparatus organelle cytoplasm intracellular membrane-bounded organelle endomembrane system protein-containing complex vesicle coat intracellular vesicle membrane protein complex COPI-coated vesicle membrane coat bounding membrane of organelle vesicle membrane cytoplasmic vesicle coated vesicle Golgi-associated vesicle vesicle COPI vesicle coat membrane coated membrane COPI-coated vesicle membrane coated vesicle membrane cytoplasmic vesicle membrane Golgi-associated vesicle membrane organelle membrane Golgi membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR006692	COPA/B second beta-propeller domain	Domain
A, B, C	IPR019775	WD40 repeat, conserved site	Conserved Site
A, B, C	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
A, B, C	IPR016391	Coatomer subunit alpha	Family
A, B, C	IPR050844	Coatomer complex subunit	Family
A, B, C	IPR010714	Coatomer, alpha subunit, C-terminal	Domain
A, B, C	IPR001680	WD40 repeat	Repeat
A, B, C	IPR047312	Coatomer subunit alpha, WD Associated Region	Domain
A, B, C	IPR020472	G-protein beta WD-40 repeat	Repeat
A, B, C	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.