8XSU

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Dinotefuran

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, E	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family
D	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, E	Acetylcholine-binding protein	transmitter-gated monoatomic ion channel activity molecular transducer activity gated channel activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential signaling receptor activity neurotransmitter receptor activity ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity transmitter-gated channel activity transmitter-gated monoatomic ion channel activity molecular transducer activity gated channel activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential signaling receptor activity neurotransmitter receptor activity ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity transmitter-gated channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity	-	cellular anatomical structure synaptic cleft extracellular region membrane postsynapse synapse cell junction cell projection neuron projection plasma membrane bounded cell projection
D	Acetylcholine-binding protein	transmitter-gated monoatomic ion channel activity molecular transducer activity gated channel activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential signaling receptor activity neurotransmitter receptor activity ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity transmitter-gated channel activity transmitter-gated monoatomic ion channel activity molecular transducer activity gated channel activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential signaling receptor activity neurotransmitter receptor activity ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity transmitter-gated channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity	-	cellular anatomical structure synaptic cleft extracellular region membrane postsynapse synapse cell junction cell projection neuron projection plasma membrane bounded cell projection

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, E	IPR007110	Immunoglobulin-like domain	Domain
A, B, C, E	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
A, B, C, E	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
A, B, C, E	IPR006201	Neurotransmitter-gated ion-channel	Family
D	IPR007110	Immunoglobulin-like domain	Domain
D	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
D	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
D	IPR006201	Neurotransmitter-gated ion-channel	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.