9BRS

Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles

External Resource: Annotation


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
D [auth R],
E [auth T],
F [auth V]		PF03179Vacuolar (H+)-ATPase G subunit (V-ATPase_G)Vacuolar (H+)-ATPase G subunit- Coiled-coil
H [auth U]PF11698V-ATPase subunit H (V-ATPase_H_C)V-ATPase subunit H- Repeat
H [auth U]PF03224V-ATPase subunit H (V-ATPase_H_N)V-ATPase subunit H- Repeat
CA [auth 4],
DA [auth 5],
EA [auth 3]		PF00006ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)ATP synthase alpha/beta family, nucleotide-binding domainThis entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho. Domain
CA [auth 4],
DA [auth 5],
EA [auth 3]		PF22919C-terminal domain of V and A type ATP synthase (ATP-synt_VA_C)C-terminal domain of V and A type ATP synthaseThis entry represents a small alpha helical domain found at the C-terminus of a variety of ATP synthases. Domain
CA [auth 4],
DA [auth 5],
EA [auth 3]		PF02874ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)ATP synthase alpha/beta family, beta-barrel domainThis family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella. Domain
A [auth 8],
B [auth 9],
C [auth Q]		PF01991ATP synthase (E/31 kDa) subunit (vATP-synt_E)ATP synthase (E/31 kDa) subunit- Family
AA [auth 2],
BA [auth 0],
Z [auth 1]		PF00006ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)ATP synthase alpha/beta family, nucleotide-binding domainThis entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho. Domain
AA [auth 2],
BA [auth 0],
Z [auth 1]		PF22919C-terminal domain of V and A type ATP synthase (ATP-synt_VA_C)C-terminal domain of V and A type ATP synthaseThis entry represents a small alpha helical domain found at the C-terminus of a variety of ATP synthases. Domain
AA [auth 2],
BA [auth 0],
Z [auth 1]		PF16886ATPsynthase alpha/beta subunit barrel-sandwich domain (ATP-synt_ab_Xtn)ATPsynthase alpha/beta subunit barrel-sandwich domainThis barrel-sandwich domain is found in the alpha-beta catalytic subunit of VATA or V-type proton ATPase catalytic subunit at the N-terminal end. This domain has a circularly permuted topology compared to other barrel-sandwich domains. In VATA barrel ...Domain
AA [auth 2],
BA [auth 0],
Z [auth 1]		PF02874ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)ATP synthase alpha/beta family, beta-barrel domainThis family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella. Domain
FA [auth 7]PF01813ATP synthase subunit D (ATP-synt_D)ATP synthase subunit D- Family
G [auth 6]PF03223V-ATPase subunit C (V-ATPase_C)V-ATPase subunit C- Family
L [auth X]PF01990ATP synthase (F/14-kDa) subunit (ATP-synt_F)ATP synthase (F/14-kDa) subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
D [auth R],
E [auth T],
F [auth V]		V-type proton ATPase subunit G 2
H [auth U]V-type proton ATPase subunit H
K [auth f]Ribonuclease kappa
M [auth d]V-type proton ATPase subunit d 1
O [auth p]Renin receptor cytoplasmic fragment
P [auth b]V-type proton ATPase 21 kDa proteolipid subunit c''
CA [auth 4],
DA [auth 5],
EA [auth 3]		V-type proton ATPase subunit B, brain isoform
A [auth 8],
B [auth 9],
C [auth Q]		V-type proton ATPase subunit E 1
N [auth c]V-type proton ATPase subunit S1
V-type proton ATPase 16 kDa proteolipid subunit c
AA [auth 2],
BA [auth 0],
Z [auth 1]		V-type proton ATPase catalytic subunit A
FA [auth 7]V-type proton ATPase subunit D
G [auth 6]V-type proton ATPase subunit C 1
I [auth a]V-type proton ATPase 116 kDa subunit a 1
J [auth e]V-type proton ATPase subunit e 2
L [auth X]V-type proton ATPase subunit F

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
D [auth R],
E [auth T],
F [auth V]		IPR005124Vacuolar (H+)-ATPase G subunitFamily
H [auth U]IPR004908ATPase, V1 complex, subunit HFamily
H [auth U]IPR016024Armadillo-type foldHomologous Superfamily
H [auth U]IPR011989Armadillo-like helicalHomologous Superfamily
H [auth U]IPR038497ATPase, V1 complex, subunit H, C-terminal domain superfamilyHomologous Superfamily
H [auth U]IPR011987ATPase, V1 complex, subunit H, C-terminalDomain
K [auth f]IPR026770Ribonuclease kappaFamily
M [auth d]IPR036079V-type ATP synthase subunit c/d subunit superfamilyHomologous Superfamily
M [auth d]IPR035067V-type ATPase subunit C/dHomologous Superfamily
M [auth d]IPR044911V-type ATP synthase c/d subunit, domain 3 superfamilyHomologous Superfamily
M [auth d]IPR016727ATPase, V0 complex, subunit dFamily
M [auth d]IPR002843ATPase, V0 complex, c/d subunitFamily
O [auth p]IPR012493Renin receptor-likeFamily
P [auth b]IPR035921F/V-ATP synthase subunit C superfamilyHomologous Superfamily
P [auth b]IPR002379V-ATPase proteolipid subunit C-like domainDomain
P [auth b]IPR000245V-ATPase proteolipid subunitFamily
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR004100ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomain
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR005723ATPase, V1 complex, subunit BFamily
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR022879V-type ATP synthase regulatory subunit B/betaFamily
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR020003ATPase, alpha/beta subunit, nucleotide-binding domain, active siteActive Site
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR000194ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomain
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR055190ATP synthase A/B type, C-terminal domainDomain
CA [auth 4],
DA [auth 5],
EA [auth 3]		IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
A [auth 8],
B [auth 9],
C [auth Q]		IPR038495V-type ATPase subunit E, C-terminal domain superfamilyHomologous Superfamily
A [auth 8],
B [auth 9],
C [auth Q]		IPR002842V-type ATPase subunit EFamily
N [auth c]IPR046755V-type proton ATPase subunit S1, luminal domainDomain
N [auth c]IPR008388V0 complex accessory subunit Ac45Family
N [auth c]IPR046756V-type proton ATPase subunit S1/VOA1, transmembrane domainDomain
IPR035921F/V-ATP synthase subunit C superfamilyHomologous Superfamily
IPR002379V-ATPase proteolipid subunit C-like domainDomain
IPR011555V-ATPase proteolipid subunit C, eukaryoticFamily
IPR000245V-ATPase proteolipid subunitFamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR022878V-type ATP synthase catalytic alpha chainFamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR024034ATPase, F1/V1 complex, beta/alpha subunit, C-terminalHomologous Superfamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR036121ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamilyHomologous Superfamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR031686ATPsynthase alpha/beta subunit, barrel-sandwich domainDomain
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR000194ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomain
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR005725ATPase, V1 complex, subunit AFamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR004100ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomain
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR023366ATP synthase subunit alpha, N-terminal domain-like superfamilyHomologous Superfamily
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR020003ATPase, alpha/beta subunit, nucleotide-binding domain, active siteActive Site
AA [auth 2],
BA [auth 0],
Z [auth 1]		IPR055190ATP synthase A/B type, C-terminal domainDomain
FA [auth 7]IPR002699ATPase, V1 complex, subunit DFamily
G [auth 6]IPR004907ATPase, V1 complex, subunit CFamily
G [auth 6]IPR036132Vacuolar ATP synthase subunit C superfamilyHomologous Superfamily
I [auth a]IPR026028ATPase, V0 complex, subunit 116kDa, eukaryoticFamily
I [auth a]IPR002490V-type ATPase, V0 complex, 116kDa subunit familyFamily
J [auth e]IPR017385ATPase, V0 complex, subunit e1/e2, metazoaFamily
J [auth e]IPR008389ATPase, V0 complex, subunit e1/e2Family
L [auth X]IPR005772ATPase, V1 complex, subunit F, eukaryoticFamily
L [auth X]IPR036906ATPase, V1 complex, subunit F superfamilyHomologous Superfamily
L [auth X]IPR008218ATPase, V1 complex, subunit FFamily

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

ChainsResource LinkGroupSubgroupProtein
mpstrucTRANSMEMBRANE PROTEINS: ALPHA-HELICALVacuolar ATPase (V-ATPase)V-ATPase, state 1 with synaptophysin in brain isolated synaptic vesicles