9DE5 | pdb_00009de5

Structure of full-length HIV TAR RNA bound to HIV Tat RNA-binding domain

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth E], C [auth B], D	RNA (55-MER)	-	-	-
E [auth A]	Protein Tat	cytoskeletal protein binding protein binding binding actinin binding RNA binding trans-activation response element binding nucleic acid binding pre-miRNA binding protein domain specific binding transcription regulator activity RNA-binding transcription regulator activity phosphoric ester hydrolase activity enzyme regulator activity phosphatase inhibitor activity cytoskeletal protein binding protein binding binding actinin binding RNA binding trans-activation response element binding nucleic acid binding pre-miRNA binding protein domain specific binding transcription regulator activity RNA-binding transcription regulator activity phosphoric ester hydrolase activity enzyme regulator activity phosphatase inhibitor activity protein serine/threonine phosphatase activity catalytic activity, acting on a protein phosphatase activity phosphatase regulator activity hydrolase activity enzyme inhibitor activity protein serine/threonine phosphatase inhibitor activity phosphoprotein phosphatase activity molecular function inhibitor activity hydrolase activity, acting on ester bonds molecular function regulator activity protein phosphatase regulator activity protein phosphatase inhibitor activity catalytic activity cyclin binding cation binding ion binding metal ion binding small molecule binding	symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms symbiont-mediated suppression of host translation initiation symbiont-mediated perturbation of host process symbiont-mediated perturbation of host gene expression modulation of process of another organism biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated perturbation of host chromatin organization transcription elongation by RNA polymerase II regulation of cellular process positive regulation of DNA-templated transcription positive regulation of transcription elongation by RNA polymerase II positive regulation of biological process symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms symbiont-mediated suppression of host translation initiation symbiont-mediated perturbation of host process symbiont-mediated perturbation of host gene expression modulation of process of another organism biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated perturbation of host chromatin organization transcription elongation by RNA polymerase II regulation of cellular process positive regulation of DNA-templated transcription positive regulation of transcription elongation by RNA polymerase II positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process positive regulation of metabolic process regulation of RNA metabolic process transcription by RNA polymerase II positive regulation of biosynthetic process positive regulation of DNA-templated transcription, elongation positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of transcription by RNA polymerase II regulation of DNA-templated transcription elongation regulation of biological process positive regulation of nucleobase-containing compound metabolic process regulation of transcription elongation by RNA polymerase II biological regulation primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression positive regulation of transcription by RNA polymerase II macromolecule biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process regulation of gene expression DNA-templated transcription elongation biosynthetic process positive regulation of RNA biosynthetic process metabolic process cellular process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process symbiont-mediated perturbation of host defense response symbiont-mediated suppression of host immune response symbiont-mediated suppression of host innate immune response symbiont-mediated perturbation of host immune response symbiont-mediated perturbation of host innate immune response symbiont-mediated suppression of host signal transduction pathway symbiont-mediated suppression of host interferon-mediated signaling pathway symbiont-mediated suppression of host type I interferon-mediated signaling pathway symbiont-mediated perturbation of host signal transduction pathway viral gene expression regulation of viral process regulation of viral transcription positive regulation of viral process viral process viral transcription positive regulation of viral transcription	host intracellular membrane-bounded organelle host cellular component host intracellular part cellular anatomical structure host cell part host intracellular region host cell nucleus host cell nucleolus host cell nuclear part host intracellular organelle extracellular region host cell cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
E [auth A]	IPR001831	Immunodeficiency virus transactivating regulatory protein (Tat)	Family
E [auth A]	IPR036963	Tat domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.