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Ras-related protein Rap-1b

UniProtKB accession:  P61224
Grouped By:  Matching UniProtKB accession
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Polymer Entities matching query 32
Go to UniProtKB:  P61224
UniProtKB description:  GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
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Protein Domains
SCOP/SCOPe Domain
ECOD Domain
PFAM Domain
InterPro Domain


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