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Member 1 of 61

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1TR7_1 - Summary | Structure

Name: Type 1 fimbrin D-mannose specific adhesin

Organism: Escherichia coli

Experimental Method: X-ray

Resolution: 2.1 Å

Molecular Weight: 17.746 kDa

Beta-lactamase TEM

UniProtKB accession: P62593

Grouped By: Matching UniProtKB accession

Group Content:

Polymer Entities matching query 61

Go to UniProtKB: P62593

UniProtKB description: TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.

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